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Dimethylamiloride

CAS No.
1214-79-5
Chemical Name:
Dimethylamiloride
Synonyms
Dimethylamiloride;DMA HYDROCHLORIDE;5-dimethylamiloride;5-(N,N-Dimethyl)-amiloride;5-(N,N-DIMETHYL)AMILORIDE HCL;5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE;AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE;5-(N,N-Dimethyl)amiloride hydrochloride;3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide;3-Amino-N-carbamimidoyl-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide
CBNumber:
CB6697022
Molecular Formula:
C8H12ClN7O
Molecular Weight:
257.68
MDL Number:
MFCD00069207
MOL File:
1214-79-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18

Dimethylamiloride Properties

Melting point 216-217 °C
Density 1.68±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form Yellow solid.
pka 8.66±0.46(Predicted)
color Light yellow to yellow
InChI 1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H
InChIKey IIUPTHVVXMBJMQ-UHFFFAOYSA-N
SMILES Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N
FDA UNII 3GC547293P
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  2811
WGK Germany  -
HazardClass  6.1(b)
PackingGroup  III
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Dimethylamiloride price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A4562 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 25mg $264 2026-04-30 Buy
Sigma-Aldrich A4562 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 100mg $871 2026-04-30 Buy
Biosynth BAA21479 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 1mg $900 2026-06-04 Buy
Biosynth BAA21479 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 10mg $900 2026-06-04 Buy
Biosynth BAA21479 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 5mg $900 2026-06-04 Buy
Product number Packaging Price Buy
A4562 25mg $264 Buy
A4562 100mg $871 Buy
BAA21479 1mg $900 Buy
BAA21479 10mg $900 Buy
BAA21479 5mg $900 Buy

Dimethylamiloride Chemical Properties, Uses, Production

Uses

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

Dimethylamiloride Preparation Products And Raw materials

Raw materials

Preparation Products

Dimethylamiloride Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9729 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3057 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19087 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 027-027-59308705 18871579363 1248680011@qq.com China 9279 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58

View Latest Price from Dimethylamiloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethylamiloride pictures 2026-07-14 Dimethylamiloride
1214-79-5
$198.00-733.00 98.90% 10g TargetMol Chemicals Inc.
5-(N,N-DIMETHYL)AMILORIDE HCL 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE 3-AMINO-N-(AMINOIMINOMETHYL)-5-(DIMETHYLAMINO)-6-CHLORO-PYRAZINE-CARBOXAMIDE HYDROCHLORIDE 3-amino-n-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride DMA, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride 3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide 5-(N,N-Dimethyl)-amiloride 3-Amino-5-(N,N-dimethylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide 6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide Dimethylamiloride N-(Diaminomethylene)-3-amino-5-(dimethylamino)-6-chloropyrazine-2-carboxamide 3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide 3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide 3-azanyl-N-[bis(azanyl)methylidene]-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide DMA HYDROCHLORIDE 5-dimethylamiloride 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)- 3-Amino-N-carbamimidoyl-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide 5-(N,N-Dimethyl)amiloride hydrochloride 1214-79-5 C8H12ClN7OHCl Monovalent Ion Channels Ion Channels Sodium Channel Modulators Voltage-gated Ion Channels Amiloride and Derivatives BioChemical Cell Signaling and Neuroscience Cell Biology