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2-Chloro-6-methylpyrazine

2-Chloro-6-methylpyrazine structure

CAS No.: 38557-71-0

Chemical Name:: 2-Chloro-6-methylpyrazine

Synonyms: 6-Methyl-2-chloropyrazine;2-Methyl-6-chloropyrazine;2-CHLORO-6-METHYLPYRAZINE;2-Chloro-6-methylpyrazine97%;Pyrazine, 2-chloro-6-methyl-;2-Chloro-6-methylpyrazine >2-Chloro-6-methyl-1,4-diazine;2-Chloro-6-methylpyrazine 97%;2-Chloro-6-methylpyrazine, >=98%;2-Chloro-6-methylpyrazine ISO 9001：2015 REACH

CBNumber:: CB5283341

Molecular Formula:: C5H5ClN2

Molecular Weight:: 128.56

MDL Number:: MFCD00055032

MOL File:: 38557-71-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:15:23

Product description	Number	Pack Size	Price
2-Chloro-6-methylpyrazine Aldrich	CDS013631	1g	$230
2-Chloro-6-methylpyrazine >98.0%(GC)	C2777	1g	$93
2-Chloro-6-methylpyrazine >98.0%(GC)	C2777	5g	$372
2-Chloro-6-methylpyrazine Asreported	269159	1g	$352
2-Chloro-6-methylpyrazine Asreported	269159	2g	$452
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2-Chloro-6-methylpyrazine Properties

Melting point	49-52
Boiling point	83°C/35mmHg(lit.)
Density	1.234±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-0.89±0.10(Predicted)
form	powder to crystal
color	White to Almost white
InChI	1S/C5H5ClN2/c1-4-2-7-3-5(6)8-4/h2-3H,1H3
InChIKey	CKUVSPQGYLELRG-UHFFFAOYSA-N
SMILES	Cc1cncc(Cl)n1
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H302

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xi,Xn

Risk Statements

20/21/22-36/37/38-22

Safety Statements

22-26-36/37/39

WGK Germany

Hazard Note

Irritant

HS Code

29339900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

2-Chloro-6-methylpyrazine price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS013631	2-Chloro-6-methylpyrazine Aldrich	38557-71-0	1g	$230	2026-04-30	Buy
TCI Chemical	C2777	2-Chloro-6-methylpyrazine >98.0%(GC)	38557-71-0	1g	$93	2026-04-30	Buy
TCI Chemical	C2777	2-Chloro-6-methylpyrazine >98.0%(GC)	38557-71-0	5g	$372	2026-04-30	Buy
Usbiological	269159	2-Chloro-6-methylpyrazine Asreported	38557-71-0	1g	$352	2026-06-03	Buy
Usbiological	269159	2-Chloro-6-methylpyrazine Asreported	38557-71-0	2g	$452	2026-06-03	Buy

Product number	Packaging	Price	Buy
CDS013631	1g	$230	Buy
C2777	1g	$93	Buy
C2777	5g	$372	Buy
269159	1g	$352	Buy
269159	2g	$452	Buy

2-Chloro-6-methylpyrazine Chemical Properties,Uses,Production

Chemical Properties

Solid

Uses

2-Chloro-6-methylpyrazine was used in the synthesis of palm site inhibitors of HCV NS5B polymerase and potent dipeptidyl peptidase IV inhibitors.

Synthesis

930798-25-7

38557-71-0

Step 3: To a 5L sealed reaction tube was added (6-chloropyrazin-2-yl)acetic acid (220 g, 1.27 mol, 1.00 equiv) and deionized water (3L). The reaction mixture was stirred at 130 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently extracted with ether (2 x 3 L). The organic phases were combined, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford 238 g (73% yield) of 2-chloro-6-methylpyrazine as a yellow solid.

References

[1] Patent: US2015/31674, 2015, A1. Location in patent: Paragraph 0325; 0322

2-Chloro-6-methylpyrazine Preparation Products And Raw materials

Raw materials

Pyrimidine, 5-chloro-4-methyl- 2-Chloro-5-methylpyrazine 4-METHYL-6-CHLORO PYRIMIDINE 4-Methylimidazole Chloroform

(6-CHLOROPYRAZIN-2-YL)ACETIC ACID

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Preparation Products

2-Amino-6-methylpyrazine

2-Chloro-6-methylpyrazine Suppliers

Global( 203)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; 19817745290	bd@blocksynth.com	China	5971	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29096	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49859	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from 2-Chloro-6-methylpyrazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	2-Chloro-6-methylpyrazine 38557-71-0	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2024-03-28	2-Chloro-6-methylpyrazine 38557-71-0		25kg	98%		PNP Biotech Co. Ltd
2020-04-30	2-Chloro-6-methylpyrazine 38557-71-0		1KG	99.0%+	800 tons	Shaanxi Dideu Medichem Co. Ltd

2-Chloro-6-methylpyrazine
38557-71-0
$1.10
99.00%
Dideu Industries Group Limited

2-Chloro-6-methylpyrazine
38557-71-0
$0.00
98%
PNP Biotech Co. Ltd

2-Chloro-6-methylpyrazine
38557-71-0
99.0%+
Shaanxi Dideu Medichem Co. Ltd

2-Chloro-6-methylpyrazine Spectrum

2-Chloro-6-methylpyrazine(38557-71-0)¹HNMR

38557-71-0(2-Chloro-6-methylpyrazine)Related Search:

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2-Chloro-6-methylpyrazine 97% 2-Methyl-6-chloropyrazine 6-Methyl-2-chloropyrazine 2-Chloro-6-methylpyrazine, >=98% 2-Chloro-6-methylpyrazine97% 2-CHLORO-6-METHYLPYRAZINE 2-Chloro-6-methyl-1,4-diazine 2-Chloro-6-methylpyrazine > Pyrazine, 2-chloro-6-methyl- 2-Chloro-6-methylpyrazine ISO 9001：2015 REACH 6-chloro-2-methyl-2,5-dihydropyrazine-2,5-diide 38557-71-0 Halides Pyrazines, Pyrimidines & Pyridazines Pyrazines, Pyrimidines & Pyridazines