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2-Chloro-6-methylpyrazine

2-Chloro-6-methylpyrazine structure

CAS No.: 38557-71-0

Chemical Name:: 2-Chloro-6-methylpyrazine

Synonyms: 6-Methyl-2-chloropyrazine;2-Methyl-6-chloropyrazine;2-CHLORO-6-METHYLPYRAZINE;2-Chloro-6-methylpyrazine97%;Pyrazine, 2-chloro-6-methyl-;2-Chloro-6-methylpyrazine >2-Chloro-6-methyl-1,4-diazine;2-Chloro-6-methylpyrazine 97%;2-Chloro-6-methylpyrazine, >=98%;2-Chloro-6-methylpyrazine ISO 9001：2015 REACH

CBNumber:: CB5283341

Molecular Formula:: C5H5ClN2

Molecular Weight:: 128.56

MDL Number:: MFCD00055032

MOL File:: 38557-71-0.mol

MSDS File:: SDS

Last updated:2026-01-13 11:25:11

Product description	Number	Pack Size	Price
2-Chloro-6-methylpyrazine Aldrich	CDS013631	1g	$230
2-Chloro-6-methylpyrazine >98.0%(GC)	C2777	1g	$93
2-Chloro-6-methylpyrazine >98.0%(GC)	C2777	5g	$372
2-Chloro-6-methylpyrazine	C368855	1g	$120
2-Chloro-6-methylpyrazine 97%	OR9783	25g	$155
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2-Chloro-6-methylpyrazine Properties

Melting point	49-52
Boiling point	83°C/35mmHg(lit.)
Density	1.234±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-0.89±0.10(Predicted)
form	powder to crystal
color	White to Almost white
InChI	1S/C5H5ClN2/c1-4-2-7-3-5(6)8-4/h2-3H,1H3
InChIKey	CKUVSPQGYLELRG-UHFFFAOYSA-N
SMILES	Cc1cncc(Cl)n1
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H302

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xi,Xn

Risk Statements

20/21/22-36/37/38-22

Safety Statements

22-26-36/37/39

WGK Germany

Hazard Note

Irritant

HS Code

29339900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

2-Chloro-6-methylpyrazine price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS013631	2-Chloro-6-methylpyrazine Aldrich	38557-71-0	1g	$230	2026-03-19	Buy
TCI Chemical	C2777	2-Chloro-6-methylpyrazine >98.0%(GC)	38557-71-0	1g	$93	2026-03-19	Buy
TCI Chemical	C2777	2-Chloro-6-methylpyrazine >98.0%(GC)	38557-71-0	5g	$372	2026-03-19	Buy
TRC	C368855	2-Chloro-6-methylpyrazine	38557-71-0	1g	$120	2021-12-16	Buy
Apolloscientific	OR9783	2-Chloro-6-methylpyrazine 97%	38557-71-0	25g	$155	2021-12-16	Buy

Product number	Packaging	Price	Buy
CDS013631	1g	$230	Buy
C2777	1g	$93	Buy
C2777	5g	$372	Buy
C368855	1g	$120	Buy
OR9783	25g	$155	Buy

2-Chloro-6-methylpyrazine Chemical Properties,Uses,Production

Chemical Properties

Solid

Uses

2-Chloro-6-methylpyrazine was used in the synthesis of palm site inhibitors of HCV NS5B polymerase and potent dipeptidyl peptidase IV inhibitors.

Synthesis

930798-25-7

38557-71-0

Step 3: To a 5L sealed reaction tube was added (6-chloropyrazin-2-yl)acetic acid (220 g, 1.27 mol, 1.00 equiv) and deionized water (3L). The reaction mixture was stirred at 130 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently extracted with ether (2 x 3 L). The organic phases were combined, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford 238 g (73% yield) of 2-chloro-6-methylpyrazine as a yellow solid.

References

[1] Patent: US2015/31674, 2015, A1. Location in patent: Paragraph 0325; 0322

2-Chloro-6-methylpyrazine Preparation Products And Raw materials

Raw materials

Pyrimidine, 5-chloro-4-methyl- 2-Chloro-5-methylpyrazine 4-METHYL-6-CHLORO PYRIMIDINE 4-Methylimidazole Chloroform

(6-CHLOROPYRAZIN-2-YL)ACETIC ACID

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Preparation Products

2-Amino-6-methylpyrazine

2-Chloro-6-methylpyrazine Suppliers

Global( 204)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
PNP Biotech Co. Ltd	+8618516098983	sales@pnpbiotech.com	China	1001	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29822	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	029-81140587 +8618717328141	sales@yutbon.com	China	454	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
PNP Biotech Co. Ltd	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 2-Chloro-6-methylpyrazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	2-Chloro-6-methylpyrazine 38557-71-0	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2024-03-28	2-Chloro-6-methylpyrazine 38557-71-0	US $0.00 / kg	25kg	98%	Inquiry	PNP Biotech Co. Ltd
2020-04-30	2-Chloro-6-methylpyrazine 38557-71-0	US $0.00-0.00 / Kg	1KG	99.0%+	800 tons	Shaanxi Dideu Medichem Co. Ltd

2-Chloro-6-methylpyrazine
38557-71-0
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-Chloro-6-methylpyrazine
38557-71-0
US $0.00 / kg
98%
PNP Biotech Co. Ltd

2-Chloro-6-methylpyrazine
38557-71-0
US $0.00-0.00 / Kg
99.0%+
Shaanxi Dideu Medichem Co. Ltd

2-Chloro-6-methylpyrazine Spectrum

2-Chloro-6-methylpyrazine(38557-71-0)¹HNMR

38557-71-0(2-Chloro-6-methylpyrazine)Related Search:

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2-Chloro-6-methylpyrazine 97% 2-Methyl-6-chloropyrazine 6-Methyl-2-chloropyrazine 2-Chloro-6-methylpyrazine, >=98% 2-Chloro-6-methylpyrazine97% 2-CHLORO-6-METHYLPYRAZINE 2-Chloro-6-methyl-1,4-diazine 2-Chloro-6-methylpyrazine > Pyrazine, 2-chloro-6-methyl- 2-Chloro-6-methylpyrazine ISO 9001：2015 REACH 6-chloro-2-methyl-2,5-dihydropyrazine-2,5-diide 38557-71-0 Halides Pyrazines, Pyrimidines & Pyridazines Pyrazines, Pyrimidines & Pyridazines