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2-BROMO-5-CHLOROANILINE

2-BROMO-5-CHLOROANILINE structure

CAS No.: 823-57-4

Chemical Name:: 2-BROMO-5-CHLOROANILINE

Synonyms: Bromo-5-chloroaniline;2-BROMO-5-CHLOROANILINE;2-BROMO-5-CHLOROBENZENAMINE;2-Bromo-5-chloroaniline 97%;2-Bromo-5-chloroaniline >BenzenaMine,2-broMo-5-chloro-;2-BroMo-5-chloroaniline , 95.0%(GC&T;2-BROMO-5-CHLOROANILINE ISO 9001：2015 REACH

CBNumber:: CB6714501

Molecular Formula:: C6H5BrClN

Molecular Weight:: 206.47

MDL Number:: MFCD00672942

MOL File:: 823-57-4.mol

MSDS File:: SDS

Last updated:2025-08-08 17:45:00

Product description	Number	Pack Size	Price
2-Bromo-5-chloroaniline >97.0%(GC)(T)	B3182	1g	$16
2-Bromo-5-chloroaniline >97.0%(GC)(T)	B3182	5g	$47
2-Bromo-5-chloroaniline >97.0%(GC)(T)	B3182	25g	$140
2-Bromo-5-chloroaniline	B699448	50mg	$45
2-Bromo-5-chloroaniline 97.0%	3630-D-X6	5G	$16
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2-BROMO-5-CHLOROANILINE Properties

Melting point	38 °C
Boiling point	128 °C / 7mmHg
Density	1.722±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	soluble in Methanol
form	powder to lump
pka	1.48±0.10(Predicted)
color	White to Brown
InChI	InChI=1S/C6H5BrClN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2
InChIKey	NLEZSQHAFMZAGU-UHFFFAOYSA-N
SMILES	C1(N)=CC(Cl)=CC=C1Br

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319
Precautionary statements	P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Hazard Codes	Xi
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36/37/39
Hazard Note	Irritant
HS Code	29214200

2-BROMO-5-CHLOROANILINE price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B3182	2-Bromo-5-chloroaniline >97.0%(GC)(T)	823-57-4	1g	$16	2025-07-31	Buy
TCI Chemical	B3182	2-Bromo-5-chloroaniline >97.0%(GC)(T)	823-57-4	5g	$47	2025-07-31	Buy
TCI Chemical	B3182	2-Bromo-5-chloroaniline >97.0%(GC)(T)	823-57-4	25g	$140	2025-07-31	Buy
TRC	B699448	2-Bromo-5-chloroaniline	823-57-4	50mg	$45	2021-12-16	Buy
SynQuest Laboratories	3630-D-X6	2-Bromo-5-chloroaniline 97.0%	823-57-4	5G	$16	2021-12-16	Buy

Product number	Packaging	Price	Buy
B3182	1g	$16	Buy
B3182	5g	$47	Buy
B3182	25g	$140	Buy
B699448	50mg	$45	Buy
3630-D-X6	5G	$16	Buy

2-BROMO-5-CHLOROANILINE Chemical Properties,Uses,Production

Chemical Properties

Brown solid

Synthesis

41513-04-6

823-57-4

General procedure for the synthesis of 2-bromo-5-chloroaniline from 2-bromo-5-chloronitrobenzene: 1-bromo-4-chloro-2-nitrobenzene (140 g, 0.59 mol) was dissolved in 2.5 L of methanol and heated gently in a hot water bath at 50 °C. A solution of ammonium formate (303 g, 4.81 mol) in 500 mL of water was added slowly. Zinc powder (155 g, 2.36 mol) was carefully added in batches, taking care to control the exothermic and reflux rate of the reaction. The addition of zinc powder needs to be done carefully to avoid excess unreacted zinc residue. After completion of the reaction, it was cooled to room temperature and filtered through a pad of diatomaceous earth (Celite). The filtrate was concentrated under reduced pressure until a two-phase mixture of red oil and water appeared. The product was extracted with diethyl ether (5 × 200 mL). The organic phases were combined, dried with anhydrous sodium sulfate, decanted and concentrated under reduced pressure to give a reddish brown oil. The oil was redissolved in 150 mL of mixed dichloromethane/hexane solvent and filtered through a short column of silica gel. The filtrate was concentrated under reduced pressure to give an orange colored oil. Hexane (200 mL) was added and cooled in a dry ice bath to precipitate 2-bromo-5-chloroaniline as a light yellow solid (92.1 g, 75% yield), which was collected by vacuum filtration.

References

[1] Patent: US2005/192310, 2005, A1. Location in patent: Page/Page column 22-23
[2] Patent: US2017/158704, 2017, A1. Location in patent: Paragraph 0678; 0679
[3] Farmaco, 2003, vol. 58, # 9, p. 723 - 738
[4] European Journal of Organic Chemistry, 2018, vol. 2018, # 26, p. 3416 - 3425
[5] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890

2-BROMO-5-CHLOROANILINE Preparation Products And Raw materials

Raw materials

4-Bromo-1-chloro-2-nitrobenzene 2-Bromo-5-chloronitrobenzene Ammonium formate Methanol ZINC

Water

1of2

Preparation Products

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER 4-BROMO-3-CHLOROANILINE

2-BROMO-5-CHLOROANILINE Suppliers

Global( 209)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13619	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	967	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Shanghai Worldyang Chemical Co.,Ltd.	58

Uses of 2-Bromo-5-chloroaniline as a synthetic intermediate
2-Bromo-5-chloroaniline is a commom synthetic intermediate or materials used in pharmaceutical synthesis and other drug materi....
Nov 21，2019

View Lastest Price from 2-BROMO-5-CHLOROANILINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	2-BROMO-5-CHLOROANILINE 823-57-4	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	2-Bromo-5-chloroaniline 823-57-4	US $200.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2019-07-06	2-BROMO-5-CHLOROANILINE 823-57-4	US $1.00 / KG	1KG	95%	500KG	Career Henan Chemical Co

2-BROMO-5-CHLOROANILINE
823-57-4
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

2-Bromo-5-chloroaniline
823-57-4
US $200.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-BROMO-5-CHLOROANILINE
823-57-4
US $1.00 / KG
95%
Career Henan Chemical Co

2-BROMO-5-CHLOROANILINE Spectrum

2-BROMO-5-CHLOROANILINE(823-57-4)¹HNMR 2-BROMO-5-CHLOROANILINE(823-57-4)FT-IR

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2-Bromo-5-chloroaniline 97% 2-BROMO-5-CHLOROBENZENAMINE 2-BROMO-5-CHLOROANILINE BenzenaMine,2-broMo-5-chloro- 2-BroMo-5-chloroaniline , 95.0%(GC&T Bromo-5-chloroaniline 2-Bromo-5-chloroaniline > 2-BROMO-5-CHLOROANILINE ISO 9001：2015 REACH 823-57-4 823-54-7 Anilines, Amides & Amines Bromine Compounds Chlorine Compounds