2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
- CAS No.
- 79456-30-7
- Chemical Name:
- 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
- Synonyms
- 3-Bromo-5-(trifluoromethyl)pyridin-2-amine;3-Bromo-5-trifluoromethyl-pyridin-2-ylamine;2-Amino-3-bromo-5-(trifL;2-Amino-3-bromo-5-(trifluorome;3-bromo-5-(trifluoromethyl)pyridine-2-amine;2-Amino-3-bromo-5-(trifluoromethyl)-pyridine;2-Pyridinamine, 3-bromo-5-(trifluoromethyl)-;2-Amino-3-bromo-5-(trifluoromethyl)pyridine,97%;2-Amino-3-bromo-5-(trifluoromethyl)pyridine 98+%;3-Bromo-5-(trifluoromethyl)pyridin-2-amine, 6-Amino-5-bromo-alpha,alpha,alpha-trifluoro-3-picoline
- CBNumber:
- CB71471093
- Molecular Formula:
- C6H4BrF3N2
- Molecular Weight:
- 241.01
- MDL Number:
- MFCD07375382
- MOL File:
- 79456-30-7.mol
- MSDS File:
- SDS
| Melting point | 98-101℃ |
|---|---|
| Boiling point | 221.7±40.0 °C(Predicted) |
| Density | 1.790±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 1.79±0.49(Predicted) |
| form | solid |
| color | Light Yellow |
| InChI | InChI=1S/C6H4BrF3N2/c7-4-1-3(6(8,9)10)2-12-5(4)11/h1-2H,(H2,11,12) |
| InChIKey | KBNACDZKKVMULE-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(C(F)(F)F)C=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P280h-P305+P351+P338 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Amino-3-bromo-5-(trifluoromethyl)-pyridine price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC3431 | 2-Amino-3-bromo-5-(trifluoromethyl)pyridine 98% | 79456-30-7 | 1g | $21 | 2026-06-04 | Buy |
| AK Scientific | Y6402 | 3-Bromo-5-(trifluoromethyl)pyridin-2-amine 98%(HPLC) | 79456-30-7 | 1g | $16 | 2026-06-04 | Buy |
| AK Scientific | Y6402 | 3-Bromo-5-(trifluoromethyl)pyridin-2-amine 98%(HPLC) | 79456-30-7 | 5g | $30 | 2026-06-04 | Buy |
| AK Scientific | Y6402 | 3-Bromo-5-(trifluoromethyl)pyridin-2-amine 98%(HPLC) | 79456-30-7 | 25g | $110 | 2026-06-04 | Buy |
| AK Scientific | Y6402 | 3-Bromo-5-(trifluoromethyl)pyridin-2-amine 98%(HPLC) | 79456-30-7 | 100g | $405 | 2026-06-04 | Buy |
2-Amino-3-bromo-5-(trifluoromethyl)-pyridine Chemical Properties, Uses, Production
Uses
2-Amino-3-bromo-5-(trifluoromethyl)pyridine is a useful research chemical. It acts as a reagent used in the preparation of fluazaindolizine, a new highly effective and selective product for the control of plant parasitic nematodes.
Synthesis
74784-70-6
79456-30-7
The general procedure for the synthesis of 2-amino-3-bromo-5-trifluoromethylpyridine from 2-amino-5-trifluoromethylpyridine was as follows: 71 g of N-bromosuccinimide was added in batches to a mixture containing 65 g of 2-amino-5-trifluoromethylpyridine and 100 ml of chloroform under cooling conditions in an ice-water bath, with the temperature increasing during the reaction. Subsequently, the reaction mixture was stirred at room temperature for 1 hour. Next, the reaction mixture was heated to 80°C and stirred at this temperature for 30 minutes. Upon completion of the reaction, the mixture was cooled to room temperature and quenched by sequentially adding saturated aqueous sodium thiosulfate and saturated aqueous sodium bicarbonate, followed by extraction with chloroform. The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. Finally, the residue was purified by silica gel column chromatography to give 96 g of the target product 2-amino-3-bromo-5-trifluoromethylpyridine. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 8.27 (1H, d), 7.86 (1H, d), 5.38 (2H, brs).
References
[1] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 12, p. 1715 - 1720
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 19, p. 2777 - 2782
[3] Patent: US5861419, 1999, A
[4] Patent: US6046217, 2000, A
[5] Patent: US6004950, 1999, A
2-Amino-3-bromo-5-(trifluoromethyl)-pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Changzhou Huanling Chemical Co., Ltd. | 89803005 18206112582 | info@huanlingchem.com | China | 983 | 68 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-12-27 | 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
79456-30-7
- $1.00
- 99%
- Career Henan Chemical Co
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