Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Amino-3-chloro-5-nitropyridine

2-Amino-3-chloro-5-nitropyridine

2-Amino-3-chloro-5-nitropyridine Structure
2-Amino-3-chloro-5-nitropyridine structure
CAS No.
22353-35-1
Chemical Name:
2-Amino-3-chloro-5-nitropyridine
Synonyms
3-Chloro-5-nitro-2-pyridinamine;3-chloro-5-nitropyridin-2-amine;2-Amino-3-chloro-5-nitropyridine;2-amino 5-nitro 3-chloro pyridine;2-Pyridinamine, 3-chloro-5-nitro-;3-Chloro-5-nitro-pyridin-2-ylamine;2-AMINO-3-CHLORO-5-NITROPYRIDINE, 95+%;Pyridine,2-amino-3-chloro-5-nitro- (6CI,8CI);2-AMINO-3-CHLORO-5-NITROPYRIDINE ISO 9001：2015 REACH
CBNumber:
CB0425012
Molecular Formula:
C5H4ClN3O2
Molecular Weight:
173.56
MDL Number:
MFCD00160299
MOL File:
22353-35-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:20
Request For Quotation

2-Amino-3-chloro-5-nitropyridine Properties

Melting point 211-213℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P302+P352-P304+P340-P305+P351+P338
HS Code  2933399990

2-Amino-3-chloro-5-nitropyridine price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 261217 2-Amino-3-chloro-5-nitropyridine Asreported 22353-35-1 500mg $333 2026-06-03 Buy
Usbiological 261217 2-Amino-3-chloro-5-nitropyridine Asreported 22353-35-1 1g $529 2026-06-03 Buy
Usbiological 261217 2-Amino-3-chloro-5-nitropyridine Asreported 22353-35-1 2g $726 2026-06-03 Buy
Usbiological 261217 2-Amino-3-chloro-5-nitropyridine Asreported 22353-35-1 5g $1000 2026-06-03 Buy
Usbiological 229712 2-Amino-3-chloro-5-nitropyridine 22353-35-1 1g $259 2026-06-03 Buy
Product number Packaging Price Buy
261217 500mg $333 Buy
261217 1g $529 Buy
261217 2g $726 Buy
261217 5g $1000 Buy
229712 1g $259 Buy

2-Amino-3-chloro-5-nitropyridine Chemical Properties, Uses, Production

Synthesis

2-Amino-5-nitropyridine

4214-76-0

2-AMINO-3-CHLORO-5-NITROPYRIDINE

22353-35-1

Under argon protection, N-chlorosuccinimide (0.53 g, 3.95 mmol) was slowly added to a solution of 2-amino-5-nitropyridine (0.50 g, 3.59 mmol) in anhydrous toluene (7.18 mL). The reaction mixture was stirred continuously at 80 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and diluted with 15 mL of water. Subsequently, extraction was carried out with ethyl acetate and the organic layer was washed sequentially with saturated sodium bicarbonate solution and brine. The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure, and the resulting crude product was purified by column chromatography (silica gel 60N, gradient elution of n-hexane/ethyl acetate = 80/20 to 60/40) to afford 2-amino-3-chloro-5-nitropyridine (0.40 g, 2.30 mmol, 64% yield) as a yellow solid. The structure of the product was analyzed by nuclear magnetic resonance hydrogen spectrum (1H NMR, 500 MHz, DMSO-d6) δ 8.84 (d, J = 2.5 Hz, 1H), 8.35 (d, J = 2.5 Hz, 1H), 7.91 (brs, 1H); nuclear magnetic resonance carbon spectrum (13C NMR, 125 MHz, DMSO-d6) δ 112.58, 132.14, 135.01, 145.25, 159.75; high-resolution mass spectrometry (HRMS, ESI-TOF, m/z) calculated values of C5H4ClN3O2Na [M + Na]+: 195.9884, 197.9856, measured values: 195.9878, 197.9847 confirmed.

References

[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3853 - 3860
[2] Journal of the Chemical Society, 1951, p. 2590,2593
[3] Zhurnal Obshchei Khimii, 1940, vol. 10, p. 1827,1836
[4] Chem. Zentralbl., 1940, vol. 111, # II, p. 614

2-Amino-3-chloro-5-nitropyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-nitropyridine N-Chlorosuccinimide Toluene

Preparation Products

3-Chloro-2-hydroxy-5-nitropyridine

2-Amino-3-chloro-5-nitropyridine Suppliers

Global Suppliers ( 102)
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
PharmaBlock Sciences (Nanjing),Inc. 55
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai Ennopharm Co., Ltd. 65
China Langchem Inc. 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Raise Chemical Technology Co.,Ltd 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55
Bide Pharmatech Ltd. 60

View Latest Price from 2-Amino-3-chloro-5-nitropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-3-CHLORO-5-NITROPYRIDINE pictures 2026-09-02 2-AMINO-3-CHLORO-5-NITROPYRIDINE
22353-35-1
 $5.00 1KG 98% Henan Fengda Chemical Co., Ltd
2-AMINO-3-CHLORO-5-NITROPYRIDINE pictures 2026-08-20 2-AMINO-3-CHLORO-5-NITROPYRIDINE
22353-35-1
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-AMINO-3-CHLORO-5-NITROPYRIDINE pictures 2026-06-30 2-AMINO-3-CHLORO-5-NITROPYRIDINE
22353-35-1
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Amino-3-chloro-5-nitropyridine Spectrum

2-AMINO-3-CHLORO-5-NITROPYRIDINE(22353-35-1)1HNMR

22353-35-1 (2-Amino-3-chloro-5-nitropyridine) Related Search:

6-Amino-5-chloro-nicotinonitrile 2-Amino-3-iodo-5-nitropyridine 3-Chloro-5-(trifluoromethyl)pyridin-2-amine 3-Amino-2-chloro-4-nitropyridine 4-AMINO-2-CHLORO-3-NITROPYRIDINE
2-AMINO-5-CHLORO-3-NITROPYRIDINE 98+% GC,2-AMINO-5-CHLORO-3-NITROPYRIDINE, 98+%,2-AMINO-5-CHLORO-3-NITROPYRIDINE 2-AMINO-4-CHLORO-3-NITROPYRIDINE 2-Chloro-5-nitropyridin-4-amine 2-Amino-4-chloro-5-nitropyridine 5-Chloro-3-pyridinamine
3-Chloro-5-nitropyridine 2-Amino-6-chloro-3-nitropyridine 2-Amino-3-chloro-5-nitropyridine 3-Chloro-2-hydrazino-5-nitropyridine 2-Amino-3-chloro-5-nitro-4-picoline
2-Amino-3-chloro-5-nitro-6-picoline 6-Amino-2-chloro-3-nitropyridine 2-Amino-5-Chloro-3-NitroPyridine5409392

1of4

3-chloro-5-nitropyridin-2-amine 3-Chloro-5-nitro-2-pyridinamine Pyridine,2-amino-3-chloro-5-nitro- (6CI,8CI) 2-AMINO-3-CHLORO-5-NITROPYRIDINE, 95+% 3-Chloro-5-nitro-pyridin-2-ylamine 2-Pyridinamine, 3-chloro-5-nitro- 2-AMINO-3-CHLORO-5-NITROPYRIDINE ISO 9001：2015 REACH 2-amino 5-nitro 3-chloro pyridine 2-Amino-3-chloro-5-nitropyridine 22353-35-1 Boronic Acid Heterocycle-Pyridine series amine| alkyl chloride| nitro-compound Pyridine