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5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE structure

CAS No.: 57054-92-9

Chemical Name:: 5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE

Synonyms: 5-BroMo-2-chloro-4-Methox...;5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE;2-chloro-5-broMo-4-MethoxypyriMidine;Pyrimidine, 5-bromo-2-chloro-4-methoxy-;5-Bromo-2-chloro-4-methoxypyrimidine, >=98%;5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE ISO 9001：2015 REACH;5-Bromo-2-chloro-4-methoxy-1,3-diazine, 5-Bromo-2-chloropyrimidin-4-yl methyl ether

CBNumber:: CB7167984

Molecular Formula:: C5H4BrClN2O

Molecular Weight:: 223.46

MDL Number:: MFCD03001373

MOL File:: 57054-92-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:57:40

Product description	Number	Pack Size	Price
5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	21862	5g	$33
5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	21862	10g	$60
5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	21862	25g	$131
5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	21862	5g	$30
5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	21862	10 g	$54
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5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE Properties

Melting point	73-75 °C(Solv: hexane (110-54-3))
Boiling point	323.6±22.0 °C(Predicted)
Density	1.745±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: 15 mg/ml
form	A crystalline solid
pka	-1.35±0.29(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

Hazard Codes

Hazard Note

Irritant

HS Code

2933599590

NFPA 704

	0
2		0

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21862	5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	57054-92-9	5g	$33	2026-04-30	Buy
Cayman Chemical	21862	5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	57054-92-9	10g	$60	2026-04-30	Buy
Cayman Chemical	21862	5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	57054-92-9	25g	$131	2026-04-30	Buy
Cayman Chemical	21862	5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	57054-92-9	5g	$30	2024-03-01	Buy
Cayman Chemical	21862	5-bromo-2-chloro-4-Methoxypyrimidine ≥98%	57054-92-9	10 g	$54	2024-03-01	Buy

Product number	Packaging	Price	Buy
21862	5g	$33	Buy
21862	10g	$60	Buy
21862	25g	$131	Buy
21862	5g	$30	Buy
21862	10 g	$54	Buy

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE Chemical Properties,Uses,Production

Description

5-bromo-2-chloro-4-Methoxypyrimidine is a building block used in the chemical synthesis of halogenated heterocycles.

Uses

5-Bromo-2-chloro-4-methoxypyrimidine is a building block in the chemical synthesis.

Synthesis

36082-50-5

124-41-4

57054-92-9

To a stirred solution of 5-bromo-2,4-dichloropyrimidine (500 mg, 2.19 mmol) in methanol (5 mL) was slowly added 30% sodium methanol solution (0.40 mL, 2.26 mmol). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure. The residue was dissolved in water (5 mL) and extracted with ethyl acetate (3 x 5 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give 5-bromo-2-chloro-4-methoxypyrimidine (432 mg, 88% yield) as a white solid.LCMS-ESI (m/z): C5H4BrClN2O Calculated value: 223.4; Measured value: 224.2 [M + H]+, tR = 7.66 min (Method 2) The following is a summary of the results.

References

[1] Patent: WO2011/76419, 2011, A1. Location in patent: Page/Page column 119
[2] Patent: EP2338888, 2011, A1. Location in patent: Paragraph 0173; 0174
[3] Tetrahedron Letters, 2006, vol. 47, # 26, p. 4415 - 4418
[4] Patent: CN106588884, 2017, A. Location in patent: Paragraph 0299; 0303; 0304; 0305
[5] Patent: WO2013/90454, 2013, A2. Location in patent: Paragraph 00386

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

5-Bromo-2,4-dichloropyrimidine Sodium Methanol Sodium Methoxide

Preparation Products

5-Bromo-2-iodo-4-methoxypyrimidine

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE Suppliers

Global( 102)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9599	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29094	58
HUBEI DING KOSIN TECHNOLOGY	+8613524650931	jason@kosinbio.com	China	953	58

Supplier	Advantage
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58
HUBEI DING KOSIN TECHNOLOGY	58

View Lastest Price from 5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE 57054-92-9	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-12-20	5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE 57054-92-9	$1.00	1KG	99%	1000KGS	Career Henan Chemical Co

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE
57054-92-9
$1.10
99.00%
Dideu Industries Group Limited

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE
57054-92-9
$1.00
99%
Career Henan Chemical Co

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE Spectrum

5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE(57054-92-9)¹HNMR

57054-92-9(5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE)Related Search:

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5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE 5-BroMo-2-chloro-4-Methox... Pyrimidine, 5-bromo-2-chloro-4-methoxy- 2-chloro-5-broMo-4-MethoxypyriMidine 5-Bromo-2-chloro-4-methoxy-1,3-diazine, 5-Bromo-2-chloropyrimidin-4-yl methyl ether 5-Bromo-2-chloro-4-methoxypyrimidine, >=98% 5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE ISO 9001：2015 REACH 57054-92-9 Building Blocks Pyrimidine Heterocycle-Pyrimidine series