(R)-(-)-3-Hydroxybutyric acid, sodium salt
- CAS No.
- 13613-65-5
- Chemical Name:
- (R)-(-)-3-Hydroxybutyric acid, sodium salt
- Synonyms
- BHB Na;KTX 0101;[R]-3-Hydroxbutanoic acid;SODIUM D-3-HYDROXYBUTYRATE;SodiuM D-β-Hydroxybutyrate;sodiuM(R)-3-hydroxybutanoate;(R)-3-hydroxybutyrate sodium;Sodium (R)-3-hydroxybutyrate;optical purity ee: 99% (GLC);D-(-)-beta-Hydroxybutyricacid
- CBNumber:
- CB7172553
- Molecular Formula:
- C4H9NaO3
- Molecular Weight:
- 128.1
- MDL Number:
- MFCD00077788
- MOL File:
- 13613-65-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149-155 °C(lit.) |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]22/D 14°, c = 10 in H2O |
| Water Solubility | Water: 100 mg/mL (793.08 mM) |
| BRN | 6118796 |
| Stability | Hygroscopic |
| Cosmetics Ingredients Functions |
ANTI-SEBUM SKIN CONDITIONING - HUMECTANT PLASTICISER SKIN CONDITIONING - MISCELLANEOUS |
| InChI | InChI=1/C4H8O3.Na.H/c1-3(5)2-4(6)7;;/h3,5H,2H2,1H3,(H,6,7);;/t3-;;/s3 |
| InChIKey | DIKSWKJUJFMKBT-LPWWCTNINA-N |
| SMILES | C(C(=O)O)[C@H](O)C.[NaH] |&1:4,r| |
| UNSPSC Code | 12352001 |
| NACRES | NA.22 |
(R)-(-)-3-Hydroxybutyric acid, sodium salt price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 298360 | (R)-(?)-3-Hydroxybutyric acid sodium salt optical purity ee: 99% (GLC) | 13613-65-5 | 1g | $180 | 2026-04-30 | Buy |
| Usbiological | 289344 | Sodium (R)-3-hydroxybutanoate Asreported | 13613-65-5 | 250mg | $333 | 2026-06-03 | Buy |
| Usbiological | 289344 | Sodium (R)-3-hydroxybutanoate Asreported | 13613-65-5 | 500mg | $460 | 2026-06-03 | Buy |
| Usbiological | 289344 | Sodium (R)-3-hydroxybutanoate Asreported | 13613-65-5 | 1g | $628 | 2026-06-03 | Buy |
| Usbiological | 289344 | Sodium (R)-3-hydroxybutanoate Asreported | 13613-65-5 | 2g | $847 | 2026-06-03 | Buy |
(R)-(-)-3-Hydroxybutyric acid, sodium salt Chemical Properties, Uses, Production
Chemical Properties
mp 165-167°C
Uses
chiral synthon
Uses
(R)-(-)-3-Hydroxybutyric acid sodium salt reacts with crown ether to form a supramolecular complex, which can catalyze the regioselective ring-opening polymerization of (S)-butyrolactone to form (R)-3-hydroxybutyrate oligomers (OHBs).
Uses
Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.
Synthesis
3976-69-0
13613-65-5
In a 500 mL three-necked flask, methyl (R)-3-hydroxybutyrate (76.0 g) made from Example 1 was added, followed by 300 mL of water. The reaction temperature was controlled to be below 30 °C, and sodium hydroxide (25.8 g) was added slowly in batches over a period of 3 hours. After addition, maintain the temperature no higher than 10°C and continue to stir the reaction for 3 hours until the reaction is complete. Add 0.3 g of activated carbon and filter after continuous stirring for 0.5 hours. The filtrate was concentrated to 100 mL, at which time a large amount of solid precipitated. Crystallization was stirred at room temperature for 1 hour, centrifuged and dried in vacuum to obtain 68.9 g of (R)-(-)-3-hydroxybutyric acid sodium salt as a white solid with a yield of 85.0% and an ee value of 91.5%.
References
[1] Patent: CN107162893, 2017, A. Location in patent: Paragraph 0042; 0043
(R)-(-)-3-Hydroxybutyric acid, sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei Qianhang Pharmaceutical Technology Co., Ltd. | 13346199520 | 1356223173@qq.com | China | 61 | 58 |
| Ningbo biermann pharmaceutical technology co., LTD | 0571-82572971 13736400971 | bichem.sales01@bichem.cn | China | 47 | 58 |
| Jiangxi Zhiyan Biopharmaceutical Technology Co., Ltd | 13732973797 13970866816 | fa@zybiopharma.com | China | 46 | 58 |
| SHANGHAI KANGXIN CHEMICAL CO.,LTD | 02160717229 19821090907 | shkx@shkangxin.com.cn | China | 92 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7982 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
View Latest Price from (R)-(-)-3-Hydroxybutyric acid, sodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-12 | R)-(-)-3-Hydroxybutyric Acid, Sodium Salt
13613-65-5
|
$130.00 | 5Kg/Bag | 99% | 1000KG | Baoji Guokang Healthchem Co., Ltd. | |
 |
2026-07-19 | (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT
13613-65-5
|
$10.00 | 98%min | 10000kg | GIHI CHEMICALS CO.,LIMITED | ||
 |
2026-05-28 | (R)-3-Hydroxybutyric acid
13613-65-5
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- R)-(-)-3-Hydroxybutyric Acid, Sodium Salt
13613-65-5
- $130.00
- 99%
- Baoji Guokang Healthchem Co., Ltd.
-
- (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT
13613-65-5
- $10.00
- 98%min
- GIHI CHEMICALS CO.,LIMITED
-
- (R)-3-Hydroxybutyric acid
13613-65-5
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
