3,4-Diaminofluorobenzene
- CAS No.
- 367-31-7
- Chemical Name:
- 3,4-Diaminofluorobenzene
- Synonyms
- 4-FLUORO-1,2-PHENYLENEDIAMINE;1,2-DIAMINO-4-FLUOROBENZENE;4-FLUORO-BENZENE-1,2-DIAMINE;4-FLUORO-O-PHENYLENEDIAMINE;4-flouro-1,2-diamino benzene;4-Diaminofluorobenzene;Fluoroophenylenediamine;uorobenzene-1,2-Diamine;3,4-DIAMINOFLUOROBENZENE;4-Fluoro-2-amino-aniline
- CBNumber:
- CB7202319
- Molecular Formula:
- C6H7FN2
- Molecular Weight:
- 126.13
- MDL Number:
- MFCD00042228
- MOL File:
- 367-31-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 94-98 °C |
|---|---|
| Boiling point | 266.1±20.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.22±0.10(Predicted) |
| color | deep brown |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Light Sensitive |
| BRN | 2081075 |
| InChI | InChI=1S/C6H7FN2/c7-4-1-2-5(8)6(9)3-4/h1-3H,8-9H2 |
| InChIKey | KWEWNOOZQVJONF-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=C(F)C=C1N |
| CAS DataBase Reference | 367-31-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN2811 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29215110 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3,4-Diaminofluorobenzene price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 653586 | 4-Fluoro-1,2-phenylenediamine 97% | 367-31-7 | 5g | $140 | 2026-04-30 | Buy |
| TCI Chemical | D3726 | 4-Fluoro-1,2-phenylenediamine >98.0%(GC)(T) | 367-31-7 | 5g | $384 | 2026-04-30 | Buy |
| TRC | TRC-F596350-5G | 4-Fluoro-1,2-phenylenediamine | 367-31-7 | 5g | $91 | 2026-06-03 | Buy |
| TRC | TRC-F596350-25G | 4-Fluoro-1,2-phenylenediamine | 367-31-7 | 25g | $332 | 2026-06-03 | Buy |
| TRC | TRC-F596350-10G | 4-Fluoro-1,2-phenylenediamine | 367-31-7 | 10g | $154 | 2026-06-03 | Buy |
3,4-Diaminofluorobenzene Chemical Properties, Uses, Production
Chemical Properties
White to brown powder
Uses
4-Fluoro-o-phenylenediamine is used as pharmaceutical intermediate.
Synthesis
2369-11-1
367-31-7
General procedure for the synthesis of 4-fluoro-1,2-benzenediamine from 5-fluoro-2-nitroaniline: a methanol solution of 5-fluoro-2-nitroaniline (0.32 M) was added to a palladium/carbon catalyst (5% w/w, 10% w). The reaction mixture was stirred for 2 h at room temperature under hydrogen atmosphere (50 psi). Upon completion of the reaction, the mixture was filtered to remove the catalyst and the filtrate was concentrated to afford 4-fluoro-1,2-benzenediamine in 90% yield as a brown oil. Mass spectrometry (electrospray positive ion mode) analysis: the theoretical molecular weight of C6H7FN2 was 126 and the measured value was 127 (M + H)+.
References
[1] Macromolecules, 2005, vol. 38, # 2, p. 297 - 306
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994, # 19, p. 2751 - 2758
[3] Patent: WO2010/13037, 2010, A1. Location in patent: Page/Page column 67
[4] Synlett, 2018, vol. 29, # 13, p. 1765 - 1768
[5] Tetrahedron, 2017, vol. 73, # 27-28, p. 3898 - 3904
3,4-Diaminofluorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Changzhou Huanling Chemical Co., Ltd. | 89803005 18206112582 | info@huanlingchem.com | China | 983 | 68 |
View Latest Price from 3,4-Diaminofluorobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-06-18 | 3,4-Diaminofluorobenzene
367-31-7
|
$1.00 | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-02-21 | 4-Fluorobenzene-1,2-diamine
367-31-7
|
1KG | 98.4% | 100 tons | Honest Joy Holdings Limited | ||
 |
2020-01-09 | 3,4-Diaminofluorobenzene
367-31-7
|
$1.00 | 1KG | 99.0% | 100kg | Career Henan Chemical Co |
-
- 3,4-Diaminofluorobenzene
367-31-7
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-Fluorobenzene-1,2-diamine
367-31-7
- $0.00
- 98.4%
- Honest Joy Holdings Limited
-
- 3,4-Diaminofluorobenzene
367-31-7
- $1.00
- 99.0%
- Career Henan Chemical Co
