(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine
- CAS No.
- 207129-35-9
- Chemical Name:
- (1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine
- Synonyms
- QCI;QUINCORINE;Quincorine >Quincorine (QCI);(1S 2S 5R)-2-HYDROXYMETHYL-5-VINYL- &;(1S,2S,5R)-5-Vinyl-2-quinuclidinemethanol;(2S,4S,5R)-5-VINYLQUINUCLIDINE-2-METHANOL;(1S,2S,5S)-5-VINYL-2-QUINUCLIDINEMETHANOL;((1S,2S,5S)-5-Vinylquinuclidin-2-yl)methanol;(2S,4S,5R)-2-HYDROXYMETHYL-5-VINYLQUINUCLIDINE
- CBNumber:
- CB7205941
- Molecular Formula:
- C10H17NO
- Molecular Weight:
- 167.25
- MDL Number:
- MFCD08276491
- MOL File:
- 207129-35-9.mol
- TDS File:
- TDS
| Melting point | 25-27 °C(lit.) |
|---|---|
| Boiling point | 270 °C(lit.) |
| Density | 1.051 g/mL at 20 °C(lit.) |
| refractive index | 39 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| pka | 14.70±0.10(Predicted) |
| form | powder to lump to clear liquid |
| color | White or Colorless to Yellow |
(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | Q0074 | Quincorine >98.0%(GC) | 207129-35-9 | 1g | $456 | 2024-03-01 | Buy |
| TCI Chemical | Q0074 | Quincorine >98.0%(GC) | 207129-35-9 | 100mg | $75 | 2024-03-01 | Buy |
| Usbiological | 288580 | Quincorine Asreported | 207129-35-9 | 50mg | $312 | 2026-06-03 | Buy |
| Usbiological | 288580 | Quincorine Asreported | 207129-35-9 | 100mg | $429 | 2026-06-03 | Buy |
| Usbiological | 288580 | Quincorine Asreported | 207129-35-9 | 250mg | $609 | 2026-06-03 | Buy |
(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine Chemical Properties, Uses, Production
Application
In 1820, it was first isolated and purified from quina bark powder and proved to be an effective drug for treating malaria. In addition to its medicinal value, quinine is also an important chiral catalyst in the field of organic synthesis and is widely used in the field of asymmetric catalysis of small organic molecules.
Synthesis
TBAF (1M solution of THF, 37 L, 0.037 mmol) was added to a solution of 21c (8 mg, 0.028 mmol) in THF (1 mL) at 0 C. The solution was allowed to warm to ambient temperature. concentrated after 12 h. (1S,2S,5S)-2-(hydroxymethyl)-5-vinylquinuclidine ring (21b, 5.1 mg, 78%) was obtained by preparative TLC (CH2Cl2 / MeOH 2:1) as an anhydrous oil.
(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine Preparation Products And Raw materials
Raw materials
Preparation Products
(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Shanghai Qiao Chemical Science Co., Ltd | 021-58892003 | info@qiaochem.com | China | 6065 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
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