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5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde structure

CAS No.: 27006-76-4

Chemical Name:: 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

Synonyms: BUTTPARK 36\18-27;TIMTEC-BB SBB005568;5-Chloro-1,3-Dimethyl-1H-Pyraz;5-Chloro-1,3-dimethyl-1H-pyrazole-4-;5-Chloro-4-formyl-1,3-dimethylpyrazole;5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE;5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE;5-chloro-1,3-dimethylpyrazole-4-carbaldehyde;5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde;5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE

CBNumber:: CB7224182

Molecular Formula:: C6H7ClN2O

Molecular Weight:: 158.59

MDL Number:: MFCD00052538

MOL File:: 27006-76-4.mol

Last updated:2025-07-24 18:13:50

Request For Quotation

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Properties

Melting point	78-79°C
Boiling point	255.7±35.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	powder to crystal
pka	-0.60±0.10(Predicted)
color	White to Yellow to Orange
CAS DataBase Reference	27006-76-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22

Safety Statements

26-37/39-36/37/39-22

RIDADR

2811

HazardClass

IRRITANT

HS Code

29124990

NFPA 704

	0
2		0

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C2747	5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde >98.0%(GC)	27006-76-4	1g	$85	2025-07-31	Buy
TCI Chemical	C2747	5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde >98.0%(GC)	27006-76-4	5g	$291	2025-07-31	Buy
TRC	C584783	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde	27006-76-4	50mg	$60	2021-12-16	Buy
Frontier Specialty Chemicals	JK118057	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 97%	27006-76-4	1g	$83	2021-12-16	Buy
Matrix Scientific	042926	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde >95%	27006-76-4	25g	$140	2021-12-16	Buy

Product number	Packaging	Price	Buy
C2747	1g	$85	Buy
C2747	5g	$291	Buy
C584783	50mg	$60	Buy
JK118057	1g	$83	Buy
042926	25g	$140	Buy

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

Off-white to brown solid

Synthesis

3201-29-4

68-12-2

27006-76-4

Step 2: Synthesis of 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde: 2,5-dimethyl-1H-pyrazol-3(2H)-one (32 g, 285.71 mmol) was mixed with POCl3 (128 mL) at 0 °C and N,N-dimethylformamide (26.35 mL, 342.85 mmol) was added slowly. The reaction mixture was warmed to 100 °C and stirred for 7 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was alkalized with aqueous sodium bicarbonate and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford the target compound 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde (28 g, 62.0% yield).

References

[1] Patent: WO2015/10049, 2015, A1. Location in patent: Paragraph 0712; 0713
[2] Patent: WO2015/200650, 2015, A1. Location in patent: Paragraph 0519; 0522-0523
[3] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0221; 0224; 0225

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate N,N-Dimethylformamide Phosphorus oxitrichloride 1,3-Dimethyl-5-pyrazolone Methylhydrazine

2,5-Dimethyl-1H-pyrazol-3(2H)-one 1,3-Dimethyl-5-hydroxypyrazole

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Preparation Products

Pyrazole-1,3-dimethyl-5-phenoxy-4-carboxaldehyde oxime 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 1,3-DIMETHYL-5-MORPHOLINO-1H-PYRAZOLE-4-CARBALDEHYDE 5-(dimethylamino)-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBONITRILE

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Suppliers

Global( 178)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8826	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Changzhou Ansciep Chemical Co., Ltd.	58
HaBo Hong Kong Co., Limited.	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Spectrum

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde(27006-76-4)¹HNMR

27006-76-4(5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde)Related Search:

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ETHANE Zolpidem 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE

5-CHLORO-1,3-DIMETHYLPYRAZOLE 1H-Pyrazole-4-carboxaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

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5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE 5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE BUTTPARK 36\18-27 TIMTEC-BB SBB005568 5-Chloro-1,3-Dimethyl-1H-Pyraz 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE 1，3-dimethyl-5-chloro-1 H-pyrazole-4-carboxaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde ,97% 1,3-Dimethyl-5-chloro-1H-pyrazole-4-carbaldehyde 5-Chloro-1,3-diMethyl-4-pyrazolecarboxaldehyde 5-chloro-1,3-dimethylpyrazole-4-carbaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4- 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde> 5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde 1H-Pyrazole-4-carboxaldehyde, 5-chloro-1,3-dimethyl- 5-Chloro-4-formyl-1,3-dimethylpyrazole 5-Chloro-1,3-dimethyl-1H-pyrazol-4-carbaldehyde 5-chloro-1, 3-dimethyl-1h-pyrazol-4-formaldehyde 27006-76-4 ALDEHYDE Pyrazoles & Triazoles Aldehydes Pyrazoles & Triazoles