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ChemicalBook >> CAS DataBase List >>5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Structure
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde structure
CAS No.
27006-76-4
Chemical Name:
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
Synonyms
BUTTPARK 36\18-27;TIMTEC-BB SBB005568;5-Chloro-1,3-Dimethyl-1H-Pyraz;5-Chloro-1,3-dimethyl-1H-pyrazole-4-;5-Chloro-4-formyl-1,3-dimethylpyrazole;5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE;5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE;5-chloro-1,3-dimethylpyrazole-4-carbaldehyde;5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde;5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE
CBNumber:
CB7224182
Molecular Formula:
C6H7ClN2O
Molecular Weight:
158.59
MDL Number:
MFCD00052538
MOL File:
27006-76-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-28 09:47:26
Request For Quotation

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Properties

Melting point 78-79°C
Boiling point 255.7±35.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka -0.60±0.10(Predicted)
color White to Yellow to Orange
CAS DataBase Reference 27006-76-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-37/39-36/37/39-22
RIDADR  2811
HazardClass  IRRITANT
HS Code  29124990
NFPA 704
0
2 0

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2747 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde >98.0%(GC) 27006-76-4 1g $77 2026-04-30 Buy
TCI Chemical C2747 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde >98.0%(GC) 27006-76-4 5g $263 2026-04-30 Buy
Activate Scientific AS31612 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde 98% 27006-76-4 1g $26 2026-06-04 Buy
Activate Scientific AS31612 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde 98% 27006-76-4 5g $62 2026-06-04 Buy
Activate Scientific AS31612 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde 98% 27006-76-4 25g $135 2026-06-04 Buy
Product number Packaging Price Buy
C2747 1g $77 Buy
C2747 5g $263 Buy
AS31612 1g $26 Buy
AS31612 5g $62 Buy
AS31612 25g $135 Buy

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

Off-white to brown solid

Uses

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde is an intermediate in the synthesis of azoxystrobin.

Synthesis

2,5-Dimethyl-1H-pyrazol-3(2H)-one

3201-29-4

N,N-Dimethylformamide

68-12-2

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

27006-76-4

Step 2: Synthesis of 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde: 2,5-dimethyl-1H-pyrazol-3(2H)-one (32 g, 285.71 mmol) was mixed with POCl3 (128 mL) at 0 °C and N,N-dimethylformamide (26.35 mL, 342.85 mmol) was added slowly. The reaction mixture was warmed to 100 °C and stirred for 7 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was alkalized with aqueous sodium bicarbonate and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford the target compound 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde (28 g, 62.0% yield).

References

[1] Patent: WO2015/10049, 2015, A1. Location in patent: Paragraph 0712; 0713
[2] Patent: WO2015/200650, 2015, A1. Location in patent: Paragraph 0519; 0522-0523
[3] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0221; 0224; 0225

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate N,N-Dimethylformamide Phosphorus oxitrichloride 1,3-Dimethyl-5-pyrazolone Methylhydrazine
2,5-Dimethyl-1H-pyrazol-3(2H)-one 1,3-Dimethyl-5-hydroxypyrazole

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Preparation Products

Pyrazole-1,3-dimethyl-5-phenoxy-4-carboxaldehyde oxime 5-(3-Chlorophenoxy)-1,3-dimethyl-1H-pyrazole-4-carboxylic acid 1,3-Dimethyl-5-morpholino-1H-pyrazole-4-carbaldehyde 5-(dimethylamino)-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbonitrile

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Suppliers

Global( 180)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64

View Lastest Price from 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde pictures 2025-04-04 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde pictures 2021-07-13 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde pictures 2021-07-10 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
27006-76-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Spectrum

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde(27006-76-4)1HNMR

27006-76-4(5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde)Related Search:

Pyrazole Dimethyl fumarate Dimethyl ether Pyraclostrobin 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
Dimethyl sulfide Zolpidem tartrate Dimethyl phthalate Dimethyl sulfoxide N,N-Dimethylformamide
Ethane Zolpidem 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE 5-CHLORO-1,3-DIMETHYLPYRAZOLE
5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid 1H-Pyrazole-4-carboxaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

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5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE 5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE BUTTPARK 36\18-27 TIMTEC-BB SBB005568 5-Chloro-1,3-Dimethyl-1H-Pyraz 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE 1，3-dimethyl-5-chloro-1 H-pyrazole-4-carboxaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde ,97% 1,3-Dimethyl-5-chloro-1H-pyrazole-4-carbaldehyde 5-Chloro-1,3-diMethyl-4-pyrazolecarboxaldehyde 5-chloro-1,3-dimethylpyrazole-4-carbaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4- 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde> 5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde 1H-Pyrazole-4-carboxaldehyde, 5-chloro-1,3-dimethyl- 5-Chloro-4-formyl-1,3-dimethylpyrazole 5-Chloro-1,3-dimethyl-1H-pyrazol-4-carbaldehyde 5-chloro-1, 3-dimethyl-1h-pyrazol-4-formaldehyde 27006-76-4 ALDEHYDE Pyrazoles & Triazoles Aldehydes Pyrazoles & Triazoles