(E)-5-(2-BROMOVINYL)URACIL
- CAS No.
- 69304-49-0
- Chemical Name:
- (E)-5-(2-BROMOVINYL)URACIL
- Synonyms
- bvuracil;Ccris 5284;Brn 0744244;Brovudine 8;bromovinyluracil;Uracil Impurity 13;Brivudine Impurity 4;Brivudine Impurity F;5-(2-bromovinyl)uracil;(E)-5-(2-BROMOVINYL)URACIL
- CBNumber:
- CB7232969
- Molecular Formula:
- C6H5BrN2O2
- Molecular Weight:
- 217.02
- MDL Number:
- MFCD00132885
- MOL File:
- 69304-49-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (E)-5-(2-Bromovinyl)uracil 97% | 457442 | 250mg | $753 |
| (E)-5-(2-Bromovinyl)uracil ≥95% | 21030 | 25mg | $70 |
| (E)-5-(2-Bromovinyl)uracil ≥95% | 21030 | 50mg | $117 |
| (E)-5-(2-Bromovinyl)uracil ≥95% | 21030 | 100mg | $215 |
| (E)-5-(2-Bromovinyl)uracil ≥95% | 21030 | 250mg | $329 |
| Melting point | 189-194 °C (dec.)(lit.) |
|---|---|
| Density | 1.881 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 7.54±0.10(Predicted) |
| color | Pale Beige to Beige |
| InChI | 1S/C6H5BrN2O2/c7-2-1-4-3-8-6(11)9-5(4)10/h1-3H,(H2,8,9,10,11)/b2-1+ |
| InChIKey | BLXGZIDBSXVMLU-OWOJBTEDSA-N |
| SMILES | Br\C=C\C1=CNC(=O)NC1=O |
| EWG's Food Scores | 1 |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 2 |
| RTECS | UV9020500 |
| Storage Class | 13 - Non Combustible Solids |
(E)-5-(2-BROMOVINYL)URACIL price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 457442 | (E)-5-(2-Bromovinyl)uracil 97% | 69304-49-0 | 250mg | $753 | 2023-06-20 | Buy |
| Cayman Chemical | 21030 | (E)-5-(2-Bromovinyl)uracil ≥95% | 69304-49-0 | 25mg | $70 | 2026-04-30 | Buy |
| Cayman Chemical | 21030 | (E)-5-(2-Bromovinyl)uracil ≥95% | 69304-49-0 | 50mg | $117 | 2026-04-30 | Buy |
| Cayman Chemical | 21030 | (E)-5-(2-Bromovinyl)uracil ≥95% | 69304-49-0 | 100mg | $215 | 2026-04-30 | Buy |
| Cayman Chemical | 21030 | (E)-5-(2-Bromovinyl)uracil ≥95% | 69304-49-0 | 250mg | $329 | 2026-04-30 | Buy |
(E)-5-(2-BROMOVINYL)URACIL Chemical Properties,Uses,Production
Chemical Properties
Beige Solid
Uses
(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (HY-90006) in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.
References
[1] De Clercq, et al. Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine. J. Med. Chem. 29(2), 213-217 (1986).
(E)-5-(2-BROMOVINYL)URACIL Preparation Products And Raw materials
Raw materials
Preparation Products
(E)-5-(2-BROMOVINYL)URACIL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49890 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9945 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD | 0371-55159968 18137130222 | haifeng.zhang@pannacean.com | China | 715 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20121 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from (E)-5-(2-BROMOVINYL)URACIL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | (E)-5-(2-BROMOVINYL)URACIL
69304-49-0
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-05-11 | (E)-5-(2-Bromovinyl)uracil
69304-49-0
|
$158.00-488.00 | 10g | TargetMol Chemicals Inc. |
-

- (E)-5-(2-BROMOVINYL)URACIL
69304-49-0
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-

- (E)-5-(2-Bromovinyl)uracil
69304-49-0
- $158.00-488.00
- TargetMol Chemicals Inc.
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