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ChemicalBook >> CAS DataBase List >>(E)-5-(2-Bromovinyl)uracil

(E)-5-(2-Bromovinyl)uracil

(E)-5-(2-Bromovinyl)uracil Structure
(E)-5-(2-Bromovinyl)uracil structure
CAS No.
69304-49-0
Chemical Name:
(E)-5-(2-Bromovinyl)uracil
Synonyms
bvuracil;Ccris 5284;Brn 0744244;Brovudine 8;bromovinyluracil;Uracil Impurity 13;Brivudine Impurity 4;Brivudine Impurity F;5-(2-bromovinyl)uracil;5-[(E)-2-Bromovinyl]uracil
CBNumber:
CB7232969
Molecular Formula:
C6H5BrN2O2
Molecular Weight:
217.02
MDL Number:
MFCD00132885
MOL File:
69304-49-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:49
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(E)-5-(2-Bromovinyl)uracil Properties

Melting point 189-194 °C (dec.)(lit.)
Density 1.881
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 7.54±0.10(Predicted)
color Pale Beige to Beige
InChI 1S/C6H5BrN2O2/c7-2-1-4-3-8-6(11)9-5(4)10/h1-3H,(H2,8,9,10,11)/b2-1+
InChIKey BLXGZIDBSXVMLU-OWOJBTEDSA-N
SMILES Br\C=C\C1=CNC(=O)NC1=O
EWG's Food Scores 1
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  2
RTECS  UV9020500
Storage Class 13 - Non Combustible Solids

(E)-5-(2-Bromovinyl)uracil price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 457442 (E)-5-(2-Bromovinyl)uracil 97% 69304-49-0 250mg $753 2023-06-20 Buy
Cayman Chemical 21030 (E)-5-(2-Bromovinyl)uracil ≥95% 69304-49-0 25mg $70 2026-04-30 Buy
Cayman Chemical 21030 (E)-5-(2-Bromovinyl)uracil ≥95% 69304-49-0 50mg $117 2026-04-30 Buy
Cayman Chemical 21030 (E)-5-(2-Bromovinyl)uracil ≥95% 69304-49-0 100mg $215 2026-04-30 Buy
Cayman Chemical 21030 (E)-5-(2-Bromovinyl)uracil ≥95% 69304-49-0 250mg $329 2026-04-30 Buy
Product number Packaging Price Buy
457442 250mg $753 Buy
21030 25mg $70 Buy
21030 50mg $117 Buy
21030 100mg $215 Buy
21030 250mg $329 Buy

(E)-5-(2-Bromovinyl)uracil Chemical Properties, Uses, Production

Chemical Properties

Beige Solid

Uses

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (HY-90006) in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.

References

[1] De Clercq, et al. Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine. J. Med. Chem. 29(2), 213-217 (1986).

(E)-5-(2-Bromovinyl)uracil Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-5-(2-Bromovinyl)uracil Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Energy Chemical 61
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Hangzhou Sage Chemical Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Sigma-Aldrich 80

View Latest Price from (E)-5-(2-Bromovinyl)uracil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(E)-5-(2-BROMOVINYL)URACIL pictures 2026-06-30 (E)-5-(2-BROMOVINYL)URACIL
69304-49-0
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
(E)-5-(2-Bromovinyl)uracil pictures 2026-05-11 (E)-5-(2-Bromovinyl)uracil
69304-49-0
 $158.00-488.00 10g TargetMol Chemicals Inc.

69304-49-0 ((E)-5-(2-Bromovinyl)uracil) Related Search:

5,6-Diamino-1,3-dimethyluracil hydrate 2-(2-chloropyriMidin-5-yl)propan-2-ol 2,4-Dihydroxypyrimidine-5-carboxylic acid 6-Formyl-uracil monohydrate 5-Carboxycytosine
Orotic acid monohydrate dihydro-6-imino-1,3-dimethyluracil 6-(Hydroxymethyl)uracil dihydro-6-imino-1,3-dimethyl-3H-pyrimidine-2,4,5-trione 5-oxime Tetrahydrofuryluracil
Pyrimidine, 5-chloro-4-(chloromethyl)-2,6-dimethoxy- Pyrimidine, 4-(chloromethyl)-2,6-dimethoxy- Brivudine sorivudine (E)-5-(2-Bromovinyl)uracil
5-(Bromovinyl) 2'-deoxyuridine, [2'-3H]- (5-[5-(2-Bromovinyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]-3-hydroxytetrahydrofuran-2-yl)methyl pivalate 5-Bromovinyl-2'-deoxyuridine, [2-14C]-

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(e)-5-(2-bromoethenyl)-2,4(1h,3h)-pyrimidinedione 5-(2-bromoethenyl)-4(1(e)-3h)-pyrimidinedione 5-(2-bromovinyl)uracil bromovinyluracil bvuracil 5-(TRANS-2-BROMOVINYL)URACIL 5-[(E)-2-Bromoethenyl]uracil 5-[(E)-2-Bromovinyl]uracil 2,4(1H,3H)-Pyrimidinedione, 5-(2-bromoethenyl)-, (E)- Brn 0744244 Ccris 5284 5-[(1E)-2-Bromoethenyl]-2,4(1H,3H)-pyrimidinedione 2,4(1H,3H)-PyriMidinedione, 5-[(1E)-2-broMoethenyl]- (E)-5-(2-BroMovinyl)pyriMidine-2,4(1H,3H)-dione Brivudine Impurity ((E)-5-(2-Bromovinyl)uracil ) Brivudine Impurity 4 Brivudine Impurity F Brivudine Impurity 1 ((E)-5-(2-Bromovinyl)uracil) BrivudineImpurity1-5-uracil) 5-((E)-2-bromovinyl)pyrimidine Brovudine 8 Uracil Impurity 13 (E)-5-(2-Bromovinyl)uracil (E)-5-(2-Bromovinyl)uracil 69304-49-0 C6H6BrN2O2 Pyrimidines Halogenated Heterocycles Heterocyclic Building Blocks Building Blocks Nucleotides and Nucleosides Bases & Related Reagents Nucleotides Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines PyrimidinesHeterocyclic Building Blocks Building Blocks C6 to C8 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks