ChemicalBook >> CAS DataBase List >>1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester structure

CAS No.: 17288-32-3

Chemical Name:: 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester

Synonyms: Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate;SW-76;SWF-76;4-azaindole-2-ethyl formate;Ethyl 4-azaindole-2-carbo...;Ethyl 4-azaindole-2-carboxylate;4,4,5,7-tetramethyl-3,4-dihydrocoumarin;4-Azaindole-2-carboxylic acid ethyl ester;ethyl 1H-pyrrolo[3,2-b]pyridine-2-carbo×ylate;1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester

CBNumber:: CB72514656

Molecular Formula:: C10H10N2O2

Molecular Weight:: 190.2

MDL Number:: MFCD11053752

MOL File:: 17288-32-3.mol

MSDS File:: SDS

Last updated:2026-05-28 03:34:20

Product description	Number	Pack Size	Price
Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	OR321483	250mg	$21
Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	OR321483	1g	$24
Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	OR321483	5g	$60
Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	OR321483	25g	$287
Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	OR321483	100g	$948

Request For Quotation

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Properties

Melting point	179-181℃
Boiling point	356℃
Density	1.272
Flash point	169℃
storage temp.	Sealed in dry,Room Temperature
pka	12.67±0.40(Predicted)
Appearance	Off-white to yellow Solid
InChI	InChI=1S/C10H10N2O2/c1-2-14-10(13)9-6-8-7(12-9)4-3-5-11-8/h3-6,12H,2H2,1H3
InChIKey	NOWHXIDXMNNYBL-UHFFFAOYSA-N
SMILES	C12C=C(C(OCC)=O)NC1=CC=CN=2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H302-H319-H315
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code	2933998090

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR321483	Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	17288-32-3	250mg	$21	2026-06-04	Buy
Apolloscientific	OR321483	Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	17288-32-3	1g	$24	2026-06-04	Buy
Apolloscientific	OR321483	Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	17288-32-3	5g	$60	2026-06-04	Buy
Apolloscientific	OR321483	Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	17288-32-3	25g	$287	2026-06-04	Buy
Apolloscientific	OR321483	Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate >97%	17288-32-3	100g	$948	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR321483	250mg	$21	Buy
OR321483	1g	$24	Buy
OR321483	5g	$60	Buy
OR321483	25g	$287	Buy
OR321483	100g	$948	Buy

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Synthesis

ethyl 2-hydroxy-3-(3-nitropyridin-2-yl)acrylate

23596-34-1

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester

17288-32-3

The general procedure for the synthesis of ethyl 4-azaindole-2-carboxylate (4a-1) from the compound (CAS: 23596-34-1) was as follows: ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate (56.8 g, 0.24 mol), ethanol (850 mL), and 10% Pd/C (5.7 g, 10 wt%) were added to a 2 L thick-walled Parr reactor. The reactor was connected to the Parr hydrogenation unit and after flushing with hydrogen, the orange slurry was pressurized to 45 psi. the reaction temperature was raised to 57 °C by shaking for 1 h at room temperature. After the temperature of the reaction mixture stabilized at 35°C, it was slowly heated to 40°C and maintained for 3 hr. After confirming the completion of the reaction by TLC (silica gel plate, unfolding agent was CH2Cl2 solution with 1% MeOH), the reaction mixture was cooled to room temperature, the slurry was filtered through Celite and the filter cake was washed with ethanol (4 x 200 mL). The yellow filtrate was concentrated to obtain a solid (41.6 g), to which ethyl acetate (302 mL) was added and heated on a steam bath. After cooling the mixture to room temperature, heptane (600 mL) was added to precipitate the product. The mixture was stirred in an ice bath for 1 hour and then filtered and the filter cake was washed with heptane (100 mL). The filter cake was dried at 50 °C, 0.1 mmHg for 24 h to give light gray solid 4a-1 (36.6 g, 81% yield).1H NMR (DMSO-d6) δ 1.36 (t, 3H, J=7.0 Hz), 4.36 (q, 2H, J=7.0 Hz), 7.19 (s, 1H), 7.25 (dd, 1H, J=4.5, 8.1 Hz), 7.82 (d, 1H, J=8.1 Hz), 8.44 (d, 1H, J=4.5 Hz), 12.11 (s, 1H).

References

[1] Organic Process Research and Development, 2011, vol. 15, # 5, p. 1040 - 1045
[2] Patent: US2005/131012, 2005, A1. Location in patent: Page/Page column 14
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 1, p. 339 - 342

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Ethyl pyruvate ethyl 2-hydroxy-3-(3-nitropyridin-2-yl)acrylate 2-Propenoic acid, 2-hydroxy-3-(3-nitro-2-pyridinyl)-, ethyl ester, (2Z)- 2-Chloro-3-pyridinamine Ethanol

Hydrogen

1of2

Preparation Products

3-broMo-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (1H-Pyrrolo[3,2-b]pyridin-2-yl)MethanaMine

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Suppliers

Global( 99)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30224	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52704	58
PT CHEM GROUP LIMITED	+86-85511178; +86-85511178	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49895	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester 17288-32-3	$5.00	1KG	98%	100KG	Career Henan Chemical Co

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester
17288-32-3
$5.00
98%
Career Henan Chemical Co

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Spectrum

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester(17288-32-3)¹HNMR

17288-32-3(1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester)Related Search:

Ethyl indole-3-carboxylate 4-HYDROXY-7-AZAINDOLE 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE 4-Chloro-7-azaindole 4-Bromo-7-azaindole

Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexane-1-carboxylate 6-carboxy-1-(2,4-dichlorobenzyl)-2-methylbenzimidazole 3-BroMo-5-nitro-1H-pyrazo... 1-Hydroxy-1-cyclopropanecarboxylic acid 1H-PYRROLO[2,3-B]PYRIDIN-5-OL

Diethyl 1H-pyrrole-2,4-dicarboxylate 7-Azabicyclo[2,2,1]heptane hydrochloride 6-Methoxyindole 6-BROMO-4-INDOLECARBOXYLIC ACID METHYL ESTER Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate

Acetic acid, [(5-chloro-2-pyridinyl)aMino]oxo- 4-Chloro-5-fluoro-2-(Meth... 1-Benzylazetidin-3-ol

1of4

1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester Ethyl 4-azaindole-2-carboxylate Ethyl 4-azaindole-2-carbo... ethyl 1H-pyrrolo[3,2-b]pyridine-2-carbo×ylate 4-Azaindole-2-carboxylic acid ethyl ester 4,4,5,7-tetramethyl-3,4-dihydrocoumarin SWF-76 SW-76 4-azaindole-2-ethyl formate Ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate 17288-32-3