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ChemicalBook >> CAS DataBase List >>3',4'-Dihydroxy-2-methylpropiophenone

3',4'-Dihydroxy-2-methylpropiophenone

3',4'-Dihydroxy-2-methylpropiophenone Structure
3',4'-Dihydroxy-2-methylpropiophenone structure
CAS No.
5466-89-7
Chemical Name:
3',4'-Dihydroxy-2-methylpropiophenone
Synonyms
U-0521;U-0521,98+%;U0521,U 0521;3’,4’-dihydroxyisobutyrophenone;3’,4’-dihydroxy-isobutyrophenon;3',4'-Dihydroxy-2-methylpropiophenone;3',4'-Dihydroxy-α-methylpropiophenone;3’,4’-dihydroxy-2-methyl-propiophenon;1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon;1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one
CBNumber:
CB7304842
Molecular Formula:
C10H12O3
Molecular Weight:
180.2
MDL Number:
MFCD00211220
MOL File:
5466-89-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:54
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3',4'-Dihydroxy-2-methylpropiophenone Properties

Melting point 79-81℃
Boiling point 372.2±27.0 °C(Predicted)
Density 1.191±0.06 g/cm3(Predicted)
RTECS NQ5605000
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form White solid.
pka 8.77±0.31(Predicted)
color Off-White to Pale Beige

3',4'-Dihydroxy-2-methylpropiophenone price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 36314 U-0521 ≥95% 5466-89-7 25mg $107 2026-04-30 Buy
Cayman Chemical 36314 U-0521 ≥95% 5466-89-7 50mg $204 2026-04-30 Buy
Cayman Chemical 36314 U-0521 ≥95% 5466-89-7 100mg $321 2026-04-30 Buy
TRC TRC-U850325-50MG U-0521 5466-89-7 50mg $256 2026-06-03 Buy
TRC TRC-U850325-25MG U-0521 5466-89-7 25mg $148 2026-06-03 Buy
Product number Packaging Price Buy
36314 25mg $107 Buy
36314 50mg $204 Buy
36314 100mg $321 Buy
TRC-U850325-50MG 50mg $256 Buy
TRC-U850325-25MG 25mg $148 Buy

3',4'-Dihydroxy-2-methylpropiophenone Chemical Properties, Uses, Production

Uses

U-0521 is an extraneuronal COMT uptake inhibitor.

Definition

ChEBI: U 0521 is a member of acetophenones.

in vivo

U-0521 (i.p.; 0-250 mg/kg; 10 min) inhibits COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity is obtained at 90 mg/kg and maximum inhibition of 90% is obtained at 250 mg/kg[1].

Animal Model:Male Sprague-Dawley rats (180-250 g)[1]
Dosage:0-250 mg/kg
Administration:i.p.; 10 min
Result:Inhibited COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity was obtained at 90mg/kg and maximum inhibition of 90% was obtained at 250 mg/kg.

3',4'-Dihydroxy-2-methylpropiophenone synthesis

14046-55-0
5466-89-7
Synthesis of 3',4'-Dihydroxy-2-methylpropiophenone from (3,4-Dimethoxyphenyl)isopropyl ketone

3',4'-Dihydroxy-2-methylpropiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

3',4'-Dihydroxy-2-methylpropiophenone Suppliers

Global Suppliers ( 34)
Supplier Tel Email Country ProdList Advantage
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4975 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2970 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Hangzhou Bingochem Co., Ltd. 0571-87658025 sales@bingochem.com China 21532 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43439 58
LGC Science (Shanghai) Ltd. 17717235263 17717235263 offer.de@lgcgroup.com China 38135 58
Supplier Advantage
ShangHai Angti Biotechnology Co., Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Rechem science Co., Ltd. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Hangzhou Bingochem Co., Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
LGC Science (Shanghai) Ltd. 58

View Latest Price from 3',4'-Dihydroxy-2-methylpropiophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
U-0521 pictures 2026-04-20 U-0521
5466-89-7
 $739.00-1110.00 10g TargetMol Chemicals Inc.
  • U-0521 pictures
  • U-0521
    5466-89-7
  • $739.00-1110.00
  • TargetMol Chemicals Inc.

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1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon 3’,4’-dihydroxy-2-methyl-propiophenon 3’,4’-dihydroxy-isobutyrophenon 3’,4’-dihydroxyisobutyrophenone U-0521 U-0521,98+% 1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one 3',4'-Dihydroxy-α-methylpropiophenone 1-Propanone, 1-(3,4-dihydroxyphenyl)-2-methyl- U0521,U 0521 3',4'-Dihydroxy-2-methylpropiophenone 5466-89-7