ChemicalBook >> CAS DataBase List >>(4E)-TCO-PEG4-biotin

(4E)-TCO-PEG4-biotin

CAS No.
2183440-30-2
Chemical Name:
(4E)-TCO-PEG4-biotin
Synonyms
TCO-PEG4-biotin;Biotin-PEG4-TCO;Biotin-PEG5-TCO;(4E)-TCO-PEG4-biotin;PEG20000 Intermediate;PEG10000 Intermediate;Toxin-Antibody Conjugate;FITC-Labeled Intermediate;Bifunctional DBCO-PEG-MMAE;Phycoerythrin Intermediate
CBNumber:
CB54849385
Molecular Formula:
C29H50N4O8S
Molecular Weight:
614.8
MDL Number:
MFCD31561115
MOL File:
2183440-30-2.mol
MSDS File:
SDS
Last updated:2026-05-28 03:14:08

(4E)-TCO-PEG4-biotin Properties

Boiling point 837.0±65.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
pka 11.95±0.46(Predicted)

SAFETY

Risk and Safety Statements

(4E)-TCO-PEG4-biotin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114510 TCO-PEG4-biotin ≥98% 2183440-30-2 5mg $780 2026-06-04 Buy
BroadPharm bp-23847 TCO-PEG4-biotin 95% 2183440-30-2 10MG $320 2026-05-24 Buy
BroadPharm bp-23847 TCO-PEG4-biotin 95% 2183440-30-2 25MG $540 2026-05-24 Buy
BroadPharm bp-23847 TCO-PEG4-biotin 95% 2183440-30-2 50MG $860 2026-05-24 Buy
aablocks AA019EEA Cyclooct-4-en-1-yl (16-oxo-20-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9,12-tetraoxa-15-azaicosyl)carbamate 95% 2183440-30-2 5mg $110 2026-05-29 Buy
Product number Packaging Price Buy
CS-0114510 5mg $780 Buy
bp-23847 10MG $320 Buy
bp-23847 25MG $540 Buy
bp-23847 50MG $860 Buy
AA019EEA 5mg $110 Buy

(4E)-TCO-PEG4-biotin Chemical Properties,Uses,Production

Description

TCO-PEG4-biotin is a biotinylation reagent containing TCO moieties. TCO enable click chemistry with tetrazine. The hydrophilic PEG spacer improves the water solubility of compounds.

Uses

TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001

(4E)-TCO-PEG4-biotin Preparation Products And Raw materials

Raw materials

Preparation Products

(4E)-TCO-PEG4-biotin Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 13892832556 2440688701@qq.com China 1977 58
Hangzhou Taorui Biotechnology Co., Ltd QQ1259737804 15268198094 sales@torreybio.com China 4128 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Xi'an Qiyue Biotechnology Co., Ltd. 400-400-6966-012-012 17778955912 2957605606@qq.com China 3988 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Shanxi Nuocheng Biotechnology Co., Ltd 17835231871 572710841@qq.com China 7836 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38862 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com 18017580634 hanfangpharma@126.com China 25800 58

View Lastest Price from (4E)-TCO-PEG4-biotin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-PEG4-TCO pictures 2025-06-07 Biotin-PEG4-TCO
2183440-30-2
1mg >95.00% 1mg Xian confluore Biological Technology Co., Ltd.
  • Biotin-PEG4-TCO pictures
  • Biotin-PEG4-TCO
    2183440-30-2
  • $0.00
  • >95.00%
  • Xian confluore Biological Technology Co., Ltd.
(4E)-TCO-PEG4-biotin Biotin-PEG4-TCO TCO-PEG4-biotin 5,8,11,14-Tetraoxa-2,17-diazadocosanoic acid, 22-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-18-oxo-, 4-cycloocten-1-yl ester Novel Adjuvant TLR7 Agonist EVs Stability PEG Modifier Phycoerythrin Intermediate Fluorescent Upconversion Nanoparticle Intermediate Bifunctional DBCO-PEG-MMAE Fluorescent Label Intermediate PEG20000 Intermediate ADC Cell-Penetrating Peptide Intermediate ADC Internalization Promoting Intermediate PEG10000 Intermediate mPEG-succinimidyl carboxymethyl Intermediate mPEG-iodoacetamide Intermediate ADC Ultrasound Responsive Linker PROTACs Cellular Uptake Promoter miRNA Modification Intermediate PEG-dimaleimide Intermediate mTOR Inhibitor Intermediate IGFR Inhibitor Intermediate FITC-Labeled Intermediate LAG-3 Inhibitor Intermediate OX40 Inhibitor Intermediate CRISPR-Cas9 Enzyme Modifier Cell Therapy Oxidative Stress Protector mRNA 2'-O-Methyluridine Monomer RDC Peptide Carrier-Chelator Conjugation Intermediate Toxin-Antibody Conjugate Biotin-PEG5-TCO 2183440-30-2 peg