Z-Abu-OH
- CAS No.
- 42918-86-5
- Chemical Name:
- Z-Abu-OH
- Synonyms
- 02906;Z-D-Abu;Z-Abu-OH;Nsc164666;Cbz-2-Abu;Z-L-Abu-OH;Z-2-ABU-OH;Cbz-Abu-OH;Z-D-Abu-OH;Z-ABU(2)-OH
- CBNumber:
- CB7343296
- Molecular Formula:
- C12H15NO4
- Molecular Weight:
- 237.25
- MDL Number:
- MFCD00077006
- MOL File:
- 42918-86-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| NFPA 704 |
|
Z-Abu-OH price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 465268 | S-2-(((Benzyloxy)carbonyl)amino)butanoic Acid | 50mg | $326 | 2026-06-03 | Buy | |
| Usbiological | 465268 | S-2-(((Benzyloxy)carbonyl)amino)butanoic Acid | 100mg | $446 | 2026-06-03 | Buy | |
| Usbiological | 260526 | Z-L-alpha-aminobutyric acid Asreported | 42918-86-5 | 2g | $333 | 2026-06-03 | Buy |
| Usbiological | 260526 | Z-L-alpha-aminobutyric acid Asreported | 42918-86-5 | 5g | $465 | 2026-06-03 | Buy |
| Usbiological | 260526 | Z-L-alpha-aminobutyric acid Asreported | 42918-86-5 | 10g | $623 | 2026-06-03 | Buy |
Z-Abu-OH Chemical Properties, Uses, Production
Chemical Properties
White crystalline powder
Uses
(S)-Cbz-2-aminobutyric Acid can be used as inhibitors in treatment of gastrointestinal and mental disorders.
Synthesis
1492-24-6
501-53-1
42918-86-5
To benzyl chloroformate (17.06 mL, 119 mmol) was added slowly and dropwise (S)-2-aminobutyric acid (11.2 g, 109 mmol) solution of tetrahydrofuran (THF, 200 mL) and 2M aqueous sodium carbonate (65.2 mL, 130 mmol) at 0 °C. After dropwise addition, the reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the aqueous layer was separated by extraction with H2O/tert-butyl methyl ether (TBME). The aqueous layer was acidified to pH=2 with 2M HCl aqueous solution and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and the filtrate was concentrated to afford (S)-2-(benzyloxycarbonylamino)butyric acid (22.8 g, 77% yield) as a colorless oil. The product could be used in the subsequent reaction without further purification.LC-MS analysis: [M-H] 236.2; retention time (Rt) 0.76 min (LCMS method 1).
References
[1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 9, p. 1927 - 1930
[2] Patent: US2014/135330, 2014, A1. Location in patent: Paragraph 0230
[3] Journal of the American Chemical Society, 1964, vol. 86, p. 4991 - 4999
[4] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1964, p. 635 - 640
[5] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1964, # 4, p. 685 - 692
Z-Abu-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Rate Biochemicals CO., LTD. | +86-(0)25-84931986,(0)18951962398 | China | 70 | 62 | |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
View Latest Price from Z-Abu-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Z-ABU-OH
42918-86-5
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | Z-ABU-OH
42918-86-5
|
$7.00 | 1kg | 99% | 100kg | Career Henan Chemical Co | |
 |
2019-07-06 | Z-ABU-OH
42918-86-5
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
