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Hydroxybupropione

CAS No.
92264-81-8
Chemical Name:
Hydroxybupropione
Synonyms
HYDROXYBUPROPION;C13H18ClNO2;HYDROXYBUPROPIONE;Bupropion Impurity 7;Bupropion Impurity 24;Hydroxymethyl Bupropion;(±)-Hydroxybupropion solution;(±)-Hydroxybupropion solution;Hydroxybupropione/Bupropion morpholinol;Hydroxybupropion, 1mg/ml in Acetonitrile
CBNumber:
CB7367225
Molecular Formula:
C13H18ClNO2
Molecular Weight:
255.74
MDL Number:
MFCD03701187
MOL File:
92264-81-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:43:35

Hydroxybupropione Properties

Melting point 121-123°C
Boiling point 393.9±32.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
Flash point 2℃
storage temp. -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form Solid
pka 15.43±0.10(Predicted)
color White to Pale Yellow
Major Application clinical testing
InChI 1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3
InChIKey RCOBKSKAZMVBHT-UHFFFAOYSA-N
SMILES ClC1=CC(C2(O)C(C)NC(C)(C)CO2)=CC=C1
FDA UNII V94F513635
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37
RIDADR  UN 1648 3 / PGII
WGK Germany  2
HS Code  3822900000
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2

Hydroxybupropione price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H-066 (±)-Hydroxybupropion solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 92264-81-8 1mL $60.9 2026-04-30 Buy
Biosynth SDA26481 Hydroxybupropion 92264-81-8 25mg $1265 2026-06-05 Buy
Biosynth SDA26481 Hydroxybupropion 92264-81-8 50mg $1650 2026-06-05 Buy
ChemScene CS-0019871 Hydroxybupropion 99.91% 92264-81-8 5mg $271 2026-06-04 Buy
ChemScene CS-0019871 Hydroxybupropion 99.91% 92264-81-8 10mg $422 2026-06-04 Buy
Product number Packaging Price Buy
H-066 1mL $60.9 Buy
SDA26481 25mg $1265 Buy
SDA26481 50mg $1650 Buy
CS-0019871 5mg $271 Buy
CS-0019871 10mg $422 Buy

Hydroxybupropione Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496

Definition

ChEBI: Hydroxybupropion is an aromatic ketone.

General Description

(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin and Zyban. This Certified Spiking Solution is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

Hydroxybupropione Preparation Products And Raw materials

Raw materials

Preparation Products

Hydroxybupropione Suppliers

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Artis Chemistry (Shanghai) Co. Ltd. 86-21-60936353 China 335 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Artis Biotech Co. Ltd. 18108108965 18108108965 sales@artisbio.com China 2503 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9609 60

Hydroxybupropione Spectrum

HYDROXYBUPROPIONE 1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE 2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE 1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine 1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one 1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone (±)-Hydroxybupropion solution Bupropion Impurity 7 Bupropion Impurity 24 1-Propanone, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]- 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino Hydroxymethyl Bupropion Hydroxybupropione/Bupropion morpholinol (±)-Hydroxybupropion solution Hydroxybupropion, 1mg/ml in Acetonitrile C13H18ClNO2 HYDROXYBUPROPION 92264-81-8 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Bupropion