Quinaldine
- CAS No.
- 91-63-4
- Chemical Name:
- Quinaldine
- Synonyms
- 2-METHYLQUINOLINE;2-Methylchinolin;QuinaL;2-Quinaldine;2-Methylpuinoiline;2-METHYLQUINOLINES;NSC-3397;Quildine;Khinaldin;QUINALDINE
- CBNumber:
- CB7373558
- Molecular Formula:
- C10H9N
- Molecular Weight:
- 143.19
- MDL Number:
- MFCD00006756
- MOL File:
- 91-63-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -2 °C |
|---|---|
| Boiling point | 248 °C |
| Density | 1.058 g/mL at 25 °C(lit.) |
| vapor pressure | <0.1 hPa (20 °C) |
| refractive index |
n |
| Flash point | 175 °F |
| storage temp. | Store below +30°C. |
| solubility | chloroform: soluble(lit.) |
| form | Crystalline Powder |
| pka | 5.83(at 20℃) |
| color | White to slightly yellow |
| PH | 6.9 (H2O, 20℃)(saturated aqueous solution) |
| Water Solubility | PRACTICALLY INSOLUBLE |
| Sensitive | Light Sensitive |
| Merck | 14,8047 |
| BRN | 110309 |
| Henry's Law Constant | 1.4×101 mol/(m3Pa) at 25℃, Ebert et al. (2023) |
| Stability | Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents. |
| Major Application |
forensics and toxicology pharmaceutical (small molecule) |
| InChI | 1S/C10H9N/c1-8-6-7-9-4-2-3-5-10(9)11-8/h2-7H,1H3 |
| InChIKey | SMUQFGGVLNAIOZ-UHFFFAOYSA-N |
| SMILES | Cc1ccc2ccccc2n1 |
| LogP | 2.59 |
| CAS DataBase Reference | 91-63-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | DVG30M0M87 |
| NIST Chemistry Reference | Quinoline, 2-methyl-(91-63-4) |
| EPA Substance Registry System | Quinaldine (91-63-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312-H315-H319-H335 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P233-P405 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 21/22-68-36/37/38 | |||||||||
| Safety Statements | 36-45-36/37/39-26 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UZ9625000 | |||||||||
| F | 8-23 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29334990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Oral Aquatic Chronic 3 Eye Irrit. 2 Muta. 2 Skin Irrit. 2 |
|||||||||
| Toxicity | LD50 orally in rats: 1.23 g/kg (Smyth) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Quinaldine price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.05805 | Quinaldine for synthesis | 91-63-4 | 100mL | $84.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.05805 | Quinaldine for synthesis | 91-63-4 | 250ML | $128 | 2026-04-30 | Buy |
| Sigma-Aldrich | 22550 | Quinaldine ≥95.0% (GC) | 91-63-4 | 250ML | $166 | 2026-04-30 | Buy |
| Sigma-Aldrich | 22550 | Quinaldine ≥95.0% (GC) | 91-63-4 | 1L | $251 | 2026-04-30 | Buy |
| TCI Chemical | Q0005 | 2-Methylquinoline >98.0%(GC)(T) | 91-63-4 | 25g | $24 | 2026-04-30 | Buy |
Quinaldine Chemical Properties,Uses,Production
Chemical Properties
Quinaldine or 2-methylquinoline is an organic compound with the formula CH3C9H6N. It is one of the methyl derivative of a heterocyclic compound quinoline. It is bioactive and is used in the preparation of various dyes. It is a colorless oil but commercial samples can appear colored.
Uses
Quinaldine is an anaesthetic used in fish transportation. Also used in anti-malaria drugs, in manufacturing dyes, food colorants , pharmaceuticals and pH indicators.
Uses
It is an anaesthetic used in fish transportation. Used in preparation of oil-soluble dyes. Also used in anti-malaria drugs, in manufacturing dyes, food colorants , pharmaceuticals and pH indicators.
Production Methods
High-temperature coal tar contains an average of 0.2% quinaldine. It is recovered from the quinoline base mixture by rectification and hydration. Quinaldine can be synthesized by the Skraup method from aniline and crotonaldehyde with sulfuric acid in the presence of a dehydrogenating agent.
Definition
ChEBI: A quinoline compound in which the quinoline skeleton is substituted at C-2 with a methyl group.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 13, p. 1279, 1976 DOI: 10.1002/jhet.5570130626
The Journal of Organic Chemistry, 52, p. 3847, 1987 DOI: 10.1021/jo00226a023
Synthesis, p. 324, 1996 DOI: 10.1055/s-1996-4221
General Description
A colorless oily liquid darkening to red-brown on exposure to air. Flash point 175°F. Denser than water and slightly soluble in water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used to make dyes, pharmaceuticals and other chemicals.
Air & Water Reactions
Slightly soluble in water.
Reactivity Profile
Quinaldine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Keep tightly closed and protected from light .
Hazard
Strong irritant to mucous membranes.
Fire Hazard
Quinaldine is probably combustible.
Purification Methods
Dry it with Na2SO4 or by refluxing with BaO, then fractionally distil it under reduced pressure and redistil it from zinc dust. Purify it further by conversion to its phosphate (m 220o) or picrate (m 192o) from which after recrystallisation, the free base is regenerated. [Packer et al. J Am Chem Soc 80 905 1958.] Its ZnCl2 complex can be used for the same purpose. [Beilstein 20 III/IV 3454, 20 V 375.]
Quinaldine Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tocopharm Co., Ltd. | +86-021-69895597 13776836200 +86-13776836200 | tocopharm@gmail.com | China | 207 | 55 |
| Shandong YingLang Chemical Co.,Ltd | 18266343295 | chen@chemwww.com | China | 4829 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
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- Nov 26,2019
View Lastest Price from Quinaldine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 2-Methylquinoline
91-63-4
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | Quinaldine
91-63-4
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-25 | Quinaldine
91-63-4
|
$1.00 | 1KG | 99 | 100MT | Henan Xiangtong Chemical Co., Ltd. |
-
- 2-Methylquinoline
91-63-4
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Quinaldine
91-63-4
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Quinaldine
91-63-4
- $1.00
- 99
- Henan Xiangtong Chemical Co., Ltd.
