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(Hydroxymethyl)-2-pyrrolidinone

(Hydroxymethyl)-2-pyrrolidinone Structure
(Hydroxymethyl)-2-pyrrolidinone structure
CAS No.
15438-71-8
Chemical Name:
(Hydroxymethyl)-2-pyrrolidinone
Synonyms
Ai3-28014;Einecs 239-451-5;IFLAB-BB F0861-0038;METHYLOLPYRROLIDONE;N-Methylol-2-pyrrolidinone;N-HYDROXYMETHYL PYRROLIDONE;1-Hydroxymethyl-2-pyrrolidone;1-Hydroxymethyl-2-pyrrolidinone;N-(Hydroxymethyl)-2-pyrrolidone;(Hydroxymethyl)-2-pyrrolidinone
CBNumber:
CB7397305
Molecular Formula:
C5H9NO2
Molecular Weight:
115.13
MDL Number:
MFCD00020873
MOL File:
15438-71-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:56
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(Hydroxymethyl)-2-pyrrolidinone Properties

Melting point 77-79.5 °C
Boiling point 185-188 °C(Press: 4 Torr)
Density 1.213±0.06 g/cm3(Predicted)
pka 13.41±0.10(Predicted)
CAS DataBase Reference 15438-71-8(CAS DataBase Reference)
FDA UNII XK7MB95ZPN
EPA Substance Registry System 2-Pyrrolidinone, 1-(hydroxymethyl)- (15438-71-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
TSCA  TSCA listed

(Hydroxymethyl)-2-pyrrolidinone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S362557 1-(HYDROXYMETHYL)-2-PYRROLIDINONE AldrichCPR 15438-71-8 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S362557 1-(HYDROXYMETHYL)-2-PYRROLIDINONE Aldrich 15438-71-8 250mg $179 2024-03-01 Buy
Matrix Scientific 180400 1-(Hydroxymethyl)pyrrolidin-2-one 15438-71-8 500.00mg $100 2026-05-18 Buy
Matrix Scientific 180400 1-(Hydroxymethyl)pyrrolidin-2-one 15438-71-8 1.00g $120 2026-05-18 Buy
Matrix Scientific 180400 1-(Hydroxymethyl)pyrrolidin-2-one 15438-71-8 5.00g $380 2026-05-18 Buy
Product number Packaging Price Buy
S362557 1 unit $197 Buy
S362557 250mg $179 Buy
180400 500.00mg $100 Buy
180400 1.00g $120 Buy
180400 5.00g $380 Buy

(Hydroxymethyl)-2-pyrrolidinone Chemical Properties,Uses,Production

Uses

1-(hydroxymethyl)pyrrolidone-2-one can be used as a pharmaceutical synthesis intermediate. If 1-(hydroxymethyl)pyrrolidone-2-one is inhaled, move the patient to fresh air; if skin contact occurs, remove contaminated clothing and thoroughly wash the skin with soap and water. If discomfort persists, seek medical attention.

Synthesis

1-(Hydroxymethyl)pyrrolidin-2-one was prepared as follows: 2-pyrrolidinone (212.4 g, 2.0 mol) and potassium hydroxide (0.6 g) were heated to 80 C and oligoformaldehyde (75.6 g, 2.6 mol) was added within 10 min and the mixture was kept at 75 C - 80 C for 1/2 hour. The desired product was then crystallized from 1 part benzene to give 227 g of 1-(hydroxymethyl)pyrrolidin-2-one (88.2%) with a melting point product at 78°-80°C.

(Hydroxymethyl)-2-pyrrolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

(Hydroxymethyl)-2-pyrrolidinone Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
TaiChem Taizhou Limited 052386810091 zcwy9518@yeah.net China 3917 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16103 58
Block Chemical Technology (Shanghai) Co., Ltd. 021-20432219 13918097649 li_jinfei@acblock-lab.com China 10032 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
Chongqing Xinboyao Biological Technology Co., LTD 19122915778 1549869036@qq.com China 500 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 17392216152 1035@dideu.com China 9991 58
Yantai Sheng Kai Lun Biological Products Co. , Ltd. 13356901049 mark@sklnchem.cn China 7954 58
Supplier Advantage
TaiChem Taizhou Limited 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Jiangsu aikang biomedical research and development co., LTD 58
Career Henan Chemica Co 58
Beijing xinyanhui pharmaceutical research and development co., LTD 58
Block Chemical Technology (Shanghai) Co., Ltd. 58
Zhengzhou convergence chemical co., LTD 58
Chongqing Xinboyao Biological Technology Co., LTD 58
Shaanxi Dideu Newmaterial Co., Ltd. 58
Yantai Sheng Kai Lun Biological Products Co. , Ltd. 58

15438-71-8((Hydroxymethyl)-2-pyrrolidinone)Related Search:

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(R)-5-HYDROXYMETHYL-2-PYRROLIDINONE P-TOLUENESULFONATE Boc-Pyr-OH dcha (Hydroxymethyl)-2-pyrrolidinone

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N-HYDROXYMETHYL PYRROLIDONE 1-(HYDROXYMETHYL)PYRROLIDIN-2-ONE METHYLOLPYRROLIDONE IFLAB-BB F0861-0038 1-(Hydroxymethyl)-2-pyrrolizinone 1-Hydroxymethyl-2-pyrrolidone 1-Hydroxymethyl-2-pyrrolidinone 2-Pyrrolidinone, 1-(hydroxymethyl)- Ai3-28014 Einecs 239-451-5 N-(Hydroxymethyl)-2-pyrrolidinone N-(Hydroxymethyl)-2-pyrrolidone N-Methylol-2-pyrrolidinone (Hydroxymethyl)-2-pyrrolidinone 15438-71-8