5-Carboxyoxindole
- CAS No.
- 102359-00-2
- Chemical Name:
- 5-Carboxyoxindole
- Synonyms
- 5-Carboxyoxindole;RARECHEM AL BO 0983;5-CARBOXY-2-OXINDOLE;5-Carboxyindol-2-one;5-Carboxyoxindole 97%;5-Carboxyl-2-oxindole;OXINDOLE-5-CARBOXYLIC ACID;2-Oxindole-5-carboxylic a...;2-Oxindole-5-carboxylic acid;2-Oxindole-5-carboxylic acid 97%
- CBNumber:
- CB7399031
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD03411961
- MOL File:
- 102359-00-2.mol
- MSDS File:
- SDS
| Melting point | 310-316°C |
|---|---|
| Boiling point | 459.8±45.0 °C(Predicted) |
| Density | 1.433±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 4.19±0.20(Predicted) |
| color | Off-White to Light Orange |
| InChI | InChI=1S/C9H7NO3/c11-8-4-6-3-5(9(12)13)1-2-7(6)10-8/h1-3H,4H2,(H,10,11)(H,12,13) |
| InChIKey | LLLKBUWXODIMEW-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(C(O)=O)C=C2)CC1=O |
| CAS DataBase Reference | 102359-00-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317 |
| Precautionary statements | P280 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36/37/39-36/37 |
| Hazard Note | Irritant |
| HS Code | 2933790090 |
5-Carboxyoxindole price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CEA35900 | 5-Carboxyoxindole | 102359-00-2 | 10g | $472 | 2026-06-04 | Buy |
| Apolloscientific | OR10403 | 2-Oxindole-5-carboxylic acid 97% | 102359-00-2 | 250mg | $22 | 2026-06-04 | Buy |
| Apolloscientific | OR10403 | 2-Oxindole-5-carboxylic acid 97% | 102359-00-2 | 1g | $56 | 2026-06-04 | Buy |
| Apolloscientific | OR10403 | 2-Oxindole-5-carboxylic acid 97% | 102359-00-2 | 5g | $213 | 2026-06-04 | Buy |
| Matrix Scientific | 068455 | 2-Oxindole-5-carboxylic acid | 102359-00-2 | 1.00g | $68 | 2026-05-18 | Buy |
5-Carboxyoxindole Chemical Properties, Uses, Production
Synthesis
65435-04-3
102359-00-2
The general procedure for the synthesis of 2-oxoindoline-5-carboxylic acid from 5-chloroacetylindone was as follows (Example 13, from Table 3): 6.7 g of 2-hydroxyindole acid was slowly added to a stirred suspension of 30 mL of dichloroethane containing 23 g of aluminum chloride under ice bath conditions. Subsequently, 11.3 g of chloroacetyl chloride was slowly added dropwise, during which hydrogen chloride gas was released. The reaction mixture was stirred for 10 minutes and then gradually warmed to 40-50°C and maintained at this temperature for 1.5 hours. The progress of the reaction was monitored by thin layer chromatography (unfolding agent: ethyl acetate, stationary phase: silica gel) to confirm complete consumption of the raw materials. Upon completion of the reaction, the mixture was cooled to room temperature and carefully poured into ice water. The resulting precipitate was collected by vacuum filtration, washed with water and dried under vacuum to give 10.3 g (98% yield) of 5-chloroacetyl-2-hydroxyindole as an off-white solid.
References
[1] Patent: US6878733, 2005, B1. Location in patent: Page/Page column 220
[2] Patent: US6878733, 2005, B1. Location in patent: Page/Page column 172
[3] Patent: US6350754, 2002, B2. Location in patent: Page column 24
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 3, p. 745 - 750
[5] Chemical and Pharmaceutical Bulletin, 1988, vol. 36, # 6, p. 2253 - 2258
5-Carboxyoxindole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Derchemist Science & Technology Co., Ltd. | 22-58627059 13920586291 | zdcomcon@126.com | China | 4094 | 50 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
View Latest Price from 5-Carboxyoxindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-06-02 | 5-Carboxyl-2-oxindole ; 5-CARBOXYOXINDOLE; in stock Factory
102359-00-2
|
$1.00 | 1kg | High quality purified Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2020-01-08 | 5-CARBOXYOXINDOLE
102359-00-2
|
$5.50 | 1KG | 98%-99% | 1kg-100kg | Career Henan Chemical Co |
-
- 5-Carboxyl-2-oxindole ; 5-CARBOXYOXINDOLE; in stock Factory
102359-00-2
- $1.00
- High quality purified Factory in China
- Chemwill Asia Co.,Ltd.
-
- 5-CARBOXYOXINDOLE
102359-00-2
- $5.50
- 98%-99%
- Career Henan Chemical Co
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