N-Hydroxy-butyramidine
- CAS No.
- 4312-91-8
- Chemical Name:
- N-Hydroxy-butyramidine
- Synonyms
- NSC 158654;NSC 111681;Butyrylhydroxamate;N-Hydroxybutyramide;Butyrohydroximic acid;N-Hydroxy-butyramidine;Butanamide, N-hydroxy-;Butyrylhydroxamic acid;N-Butyrylhydroxylamine
- CBNumber:
- CB7428870
- Molecular Formula:
- C4H9NO2
- Molecular Weight:
- 103.12
- MDL Number:
- MFCD09931604
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 125-127℃ |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: ≥25mg/mL |
| form | powder |
| color | white to tan |
| Water Solubility | H2O: ≥25mg/mL |
| InChI | 1S/C4H9NO2/c1-2-3-4(6)5-7/h7H,2-3H2,1H3,(H,5,6) |
| InChIKey | CCBCHURBDSNSTJ-UHFFFAOYSA-N |
| SMILES | CCCC(=O)NO |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
N-Hydroxy-butyramidine price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0027 | Butyrylhydroxamic acid ≥98% (HPLC) | 4312-91-8 | 25mg | $372 | 2022-05-15 | Buy |
| ChemScene | CS-0179704 | Butyrylhydroxamic acid ≥95% | 4312-91-8 | 100mg | $168 | 2026-06-04 | Buy |
| ChemScene | CS-0179704 | Butyrylhydroxamic acid ≥95% | 4312-91-8 | 250mg | $239 | 2026-06-04 | Buy |
| ChemScene | CS-0179704 | Butyrylhydroxamic acid ≥95% | 4312-91-8 | 500mg | $378 | 2026-06-04 | Buy |
| ChemScene | CS-0179704 | Butyrylhydroxamic acid ≥95% | 4312-91-8 | 1g | $483 | 2026-06-04 | Buy |
N-Hydroxy-butyramidine Chemical Properties, Uses, Production
Uses
Butyrylhydroxamic acid (N-Hydroxybutanamide) is a potent inhibitor of histone deacetylase (HDAC). Butyrylhydroxamic acid enhances memory in behavioral models of rodents and can be used as memory enhancers, mood stabilizers, and β-chain hemoglobin disease studies[1].
Biological Activity
Butyryl hydroxamic acid is a cell permeable HDAC inhibitor. Butyryl hydroxamic acid has similar potency against class I HDAC family members as 4-Phenylbutyryl hydroxamic acid (SML0026), but is approximately 5-10 fold less potent against class IIa enzymes than 4-Phenylbutyryl hydroxamic acid.
References
[1] Ruan LT, et al. A novel amidase from Brevibacterium epidermidis ZJB-07021: gene cloning, refolding and application in butyrylhydroxamic acid synthesis. J Ind Microbiol Biotechnol. 2016 Aug;43(8):1071-83. DOI:10.1007/s10295-016-1786-y
N-Hydroxy-butyramidine Preparation Products And Raw materials
Raw materials
Preparation Products
N-Hydroxy-butyramidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Block Chemical Technology (Shanghai) Co., LTD | 021-20432219 13918097649 | li_jinfei@acblock-lab.com | China | 9964 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53589 | 58 |
| Supplier | Advantage |
|---|---|
| Block Chemical Technology (Shanghai) Co., LTD | 58 |
| TargetMol | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | 58 |
