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ChemicalBook >> CAS DataBase List >>1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole Structure
1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole structure
CAS No.
132414-50-7
Chemical Name:
1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole
Synonyms
1-Benzylhexahydropyrrolo[3,4-b]pyrrole;1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole;octahydro-1-(phenylmethyl)-Pyrrolo[3,4-b]pyrrole;Pyrrolo[3,4-b]pyrrole, octahydro-1-(phenylmethyl)-;1-benzyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole;1-(phenylmethyl)-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole
CBNumber:
CB7453687
Molecular Formula:
C13H18N2
Molecular Weight:
202.3
MDL Number:
MFCD08059343
MOL File:
132414-50-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:57
Request For Quotation

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole Properties

Boiling point 304.4±17.0 °C(Predicted)
Density 1.074±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 10.80±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 072082 1-Benzyloctahydropyrrolo[3,4-b]pyrrole 132414-50-7 1.00g $166 2026-05-18 Buy
Matrix Scientific 072082 1-Benzyloctahydropyrrolo[3,4-b]pyrrole 132414-50-7 5.00g $316 2026-05-18 Buy
Matrix Scientific 072082 1-Benzyloctahydropyrrolo[3,4-b]pyrrole 132414-50-7 10.00g $532 2026-05-18 Buy
Synthonix B57066 1-Benzyloctahydropyrrolo[3,4-b]pyrrole 97% 132414-50-7 100mg $80 2026-05-06 Buy
Synthonix B57066 1-Benzyloctahydropyrrolo[3,4-b]pyrrole 97% 132414-50-7 250mg $110 2026-05-06 Buy
Product number Packaging Price Buy
072082 1.00g $166 Buy
072082 5.00g $316 Buy
072082 10.00g $532 Buy
B57066 100mg $80 Buy
B57066 250mg $110 Buy

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole Chemical Properties, Uses, Production

Uses

1-Benzyloctahydropyrrolo[3,4-b]pyrrole is used in the synthesis of intermediates as quinolone anti-bacterials.

Synthesis

Ethyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate

132414-78-9

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE

132414-50-7

General procedure for the synthesis of 1-benzyl octahydropyrrolo[3,4-B]pyrrole-5(1H)-carboxylic acid from ethyl 1-benzylhexahydropyrrolo[3,4-B]pyrrole: Ethyl 1-benzyl octahydropyrrolo[2,3-c]pyrrole-5-carboxylate (2.1 g, 7.65 mmol) was dissolved in 37% hydrochloric acid (11 mL), and the reaction was heated and refluxed for 24 hours. Upon completion of the reaction, the pH of the reaction solution was adjusted to 8 with sodium carbonate, followed by multiple extractions of the product with dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 1.4 g of 1-benzyl octahydropyrrolo[3,4-B]pyrrole (90% yield) as a brown oil, which could be used for the next reaction without further purification. Mass spectral analysis (m/z): 203.2 [MH]+.

References

[1] Patent: WO2017/21920, 2017, A1. Location in patent: Paragraph 0633; 0634
[2] Patent: US5071999, 1991, A

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole Preparation Products And Raw materials

Raw materials

Ethyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate Hydrochloric acid Water

Preparation Products

1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole Suppliers

Global Suppliers ( 74)
Supplier Tel Email Country ProdList Advantage
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Abblis Chemicals LLC +1-832-373-8299 info@abblis.com United States 322 57
Shanghai Carlow Chemicals Co., Ltd. 21-33526724 18930996265 info@carlowchem.com China 1996 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3769 55
Shanghai Tombiopharma Chemical Co. Ltd. 13391076197 tombiopharma@163.com China 4986 55
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809; info@xrpharma.com China 686 55
Supplier Advantage
Adamas Reagent, Ltd. 59
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Topbiochem Technology Co., Ltd 58
9ding chemical ( Shanghai) Limited 56
Abblis Chemicals LLC 57
Shanghai Carlow Chemicals Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
Shanghai Tombiopharma Chemical Co. Ltd. 55
Shanghai XR Chemical Technology Co., Ltd. 55

View Latest Price from 1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE pictures 2019-12-25 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE
132414-50-7
 $1.00 1KG 99% 200kg Career Henan Chemical Co

132414-50-7 (1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole) Related Search:

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester
4-Oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester 7-(tert-Butoxycarbonyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylic acid Bicyclo[2.2.2]octane-1,4-dicarboxylic acid hemimethyl ester tert-Butyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 2-Benzyl-Octahydro-Pyrrolo[3,4-C]Pyrrole HCl,2-BENZYL-OCTAHYDRO-PYRROLO [3,4-C] PYRROLE
1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole 2-Benzyl-octahydro-pyrrolo[3,4-c]pyrrole dihydrochloride Ethyl 1-benzyl-hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate Octahydro-pyrrolo[3,4-b]pyrrole 5-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole
(3aS,6aS)-1-Benzyloctahydropyrrolo[3,4-b]pyrrole 1-Benzyl-2-methyloctahydropyrrolo[3,4-b]pyrrole 2-Benzyl-octahydro-pyrrolo[3,4-c]pyrrole hydrochloride

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1-Benzylhexahydropyrrolo[3,4-b]pyrrole octahydro-1-(phenylmethyl)-Pyrrolo[3,4-b]pyrrole 1-benzyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole 1-(phenylmethyl)-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole Pyrrolo[3,4-b]pyrrole, octahydro-1-(phenylmethyl)- 1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole 132414-50-7 Heterocycles series