(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
- CAS No.
- 745055-86-1
- Chemical Name:
- (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
- Synonyms
- UBP 296;(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione;1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-
- CBNumber:
- CB7460159
- Molecular Formula:
- C15H15N3O6
- Molecular Weight:
- 333.3
- MDL Number:
- MFCD06411606
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 190.8-191.2 °C (decomp)(Solv: water (7732-18-5)) |
|---|---|
| Boiling point | 603.0±65.0 °C(Predicted) |
| Density | 1.525±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | <3.33mg/ml in 1eq. NaOH; <3.33mg/ml in DMSO |
| pka | 2.12±0.10(Predicted) |
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 257005 | UBP 296 Asreported | 745055-86-1 | 10mg | $495 | 2026-06-03 | Buy |
| Usbiological | 257005 | UBP 296 Asreported | 745055-86-1 | 50mg | $1400 | 2026-06-03 | Buy |
| Biosynth | VEB05586 | UBP 296 | 745055-86-1 | 1mg | $196.33 | 2026-06-05 | Buy |
| Biosynth | VEB05586 | UBP 296 | 745055-86-1 | 2mg | $314.12 | 2026-06-05 | Buy |
| Biosynth | VEB05586 | UBP 296 | 745055-86-1 | 5mg | $549.7 | 2026-06-05 | Buy |
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Chemical Properties,Uses,Production
Uses
UBP 296 is a novel, potent and selective kainate receptor antagonist.
Definition
ChEBI: 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid is an alpha-amino acid.
Biological Activity
Selective and potent GluR5-subunit containing kainate receptor antagonist (apparent K D = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.
storage
Store at RT
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Preparation Products And Raw materials
Raw materials
Preparation Products
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5987 | 58 |
| Guangdong Wengjiang Chemical Reagent Co.,Ltd. | 0751-2815983 13927872582 | 3008325437@qq.com | China | 9988 | 58 |
| Shaanxi Xihua Chemical Industry Co., Ltd. | 18161915376 | 1096@dideu.com | China | 485 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 |
