5-Chloro-2-furaldehyde
- CAS No.
- 21508-19-0
- Chemical Name:
- 5-Chloro-2-furaldehyde
- Synonyms
- 5-chlorofuran-2-carbaldehyde;EOS-61611;5-Chlorofurfural;TIMTEC-BB SBB004223;5-Chloro-2-furaldehyde;5-CHLORO-2-FURALDEHYDE,97%;5-Chloro-2-furaldehyde 98%;5-chlorofuran-2-carbaldeyde;5-CHLORO-2-FURALDEHYDE, 98+%;5-Chloro-2-furancarboxaldehyde
- CBNumber:
- CB7466429
- Molecular Formula:
- C5H3ClO2
- Molecular Weight:
- 130.53
- MDL Number:
- MFCD02752599
- MOL File:
- 21508-19-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 34-37 °C (lit.) |
|---|---|
| Boiling point | 70°C 10mm |
| Density | 1.361±0.06 g/cm3(Predicted) |
| Flash point | 190 °F |
| storage temp. | 2-8°C |
| solubility | Acetone (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| color | White to off-white |
| Water Solubility | Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 108401 |
| Exposure limits |
ACGIH: STEL 1000 ppm OSHA: TWA 1000 ppm(1900 mg/m3) NIOSH: IDLH 3300 ppm; TWA 1000 ppm(1900 mg/m3) |
| InChI | 1S/C5H3ClO2/c6-5-2-1-4(3-7)8-5/h1-3H |
| InChIKey | DGAUAVDWXYXXGQ-UHFFFAOYSA-N |
| SMILES | Clc1ccc(C=O)o1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29321900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
5-Chloro-2-furaldehyde price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 531456 | 5-Chloro-2-furaldehyde 98% | 21508-19-0 | 1g | $60.5 | 2023-01-07 | Buy |
| TCI Chemical | C1721 | 5-Chloro-2-furaldehyde min. 98.0 % | 21508-19-0 | 1G | $69 | 2026-04-30 | Buy |
| TCI Chemical | C1721 | 5-Chloro-2-furaldehyde min. 98.0 % | 21508-19-0 | 5G | $207 | 2026-04-30 | Buy |
| TRC | TRC-C381980-50MG | 5-Chloro-2-furaldehyde | 21508-19-0 | 50mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-C381980-500MG | 5-Chloro-2-furaldehyde | 21508-19-0 | 500mg | $122 | 2026-06-03 | Buy |
5-Chloro-2-furaldehyde Chemical Properties, Uses, Production
Synthesis
Furfural (30 mmol) and ZnCl₂ (30 mmol) were dissolved in AcOH (30 mL) and stirred at room temperature. After 1 hour, a small amount of substrate (10 mmol) in acetic acid (5 mL) was added. The mixture was stirred at 70°C for 24 hours and diluted with Et₂O (100 mL), and washed successively with 0.1 N Na₂S₂O₃ (50 mL), 0.1 N NaHCO₃ (20 mL), and brine (20 mL).
The organic phase was dried (Na₂SO₄) to remove the solvent, yielding a crude product. This crude product was purified by column chromatography or vacuum distillation to obtain 5-CHLORO-2-FURALDEHYDE, in 10% yield.Chemical Properties
White to yellow powder
Uses
(+)-1-Deoxynojirimycin hydrochloride interferes with normal processing of N-linked glycoproteins, producing reduced amounts of complex type oligosaccharides.
Uses
5-Chloro-2-furaldehyde may be used as an internal standard during the analysis of furanic compounds by reversed-phase-high performance liquid chromatography–diode array detection (RP-HPLC–DAD) method.
General Description
5-Chloro-2-furaldehyde is also known as 5-chlorofurfural. It reacts with aniline and aniline hydrochloride to form bis-(phenylamino) derivatives, without the furan ring cleavage. It also undergoes coupling with ethyl acetoacetate to form the corresponding ethyl bis-acetoacetate.
References
[1] Chemistry - A European Journal, 2016, vol. 22, # 1, p. 129 - 133
[2] Patent: WO2004/33440, 2004, A1. Location in patent: Page 238
[3] Patent: US2004/147559, 2004, A1. Location in patent: Page 121
[4] Patent: US2004/106794, 2004, A1. Location in patent: Page 122
[5] Patent: WO2005/66147, 2005, A1. Location in patent: Page/Page column 207
5-Chloro-2-furaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Nanjing Chemrui Pharmtech Co., Ltd. | 86-25-58849758 13851795789 | sales@chemrui.com | China | 47 | 62 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Beijing innoChem Science & Technology Co.,Ltd. | 400-810-7969 010-59572699 | ningzi.li@inno-chem.com.cn | China | 6122 | 55 |
View Latest Price from 5-Chloro-2-furaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 5-CHLORO-2-FURALDEHYDE
21508-19-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co | |
 |
2019-11-19 | 5-CHLORO-2-FURALDEHYDE
21508-19-0
|
1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 5-CHLORO-2-FURALDEHYDE
21508-19-0
- $1.00
- 99%
- Career Henan Chemical Co
-
- 5-CHLORO-2-FURALDEHYDE
21508-19-0
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
