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Pomalidomide-PEG2-butyl iodide

Pomalidomide-PEG2-butyl iodide Structure
Pomalidomide-PEG2-butyl iodide structure
CAS No.
1835705-72-0
Chemical Name:
Pomalidomide-PEG2-butyl iodide
Synonyms
Pomalidomide-2-2-6-I;Pomalidomide-PEG2-butyl iodide;Pomalidomide-PEG2-butyl iodide;N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[2-[(6-iodohexyl)oxy]ethoxy]acetamide;N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-{2-[(6-iodohexyl)oxy]ethoxy}acetamide;Acetamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[2-[(6-iodohexyl)oxy]ethoxy]-;Crosslinker–E3 Ligase ligand conjugate, Pomalidomide-2-2-6-I, N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2-(2-((6-iodohexyl)oxy)ethoxy)acetamide, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB74919985
Molecular Formula:
C23H28IN3O7
Molecular Weight:
585.39
MDL Number:
MFCD32173806
MOL File:
1835705-72-0.mol
MSDS File:
SDS
Last updated:2026-01-13 11:25:45
Product description Number Pack Size Price
Pomalidomide-PEG2-butyl iodide ≥95% 904724 50MG $898
Pomalidomide-amido-PEG2-buty iodide bp-44910 5MG $130
Pomalidomide-amido-PEG2-buty iodide bp-44910 10MG $230
Pomalidomide-amido-PEG2-buty iodide bp-44910 25MG $420
Pomalidomide-amido-PEG2-buty iodide bp-44910 50MG $640
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Pomalidomide-PEG2-butyl iodide Properties

Boiling point 757.7±60.0 °C(Predicted)
Density 1.588±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form powder or crystals
pka 10.68±0.40(Predicted)
InChI 1S/C23H28IN3O7/c24-10-3-1-2-4-11-33-12-13-34-14-19(29)25-16-7-5-6-15-20(16)23(32)27(22(15)31)17-8-9-18(28)26-21(17)30/h5-7,17H,1-4,8-14H2,(H,25,29)(H,26,28,30)
InChIKey NYFZCMZZMDMBEB-UHFFFAOYSA-N
SMILES ICCCCCCOCCOCC(NC1=CC=CC2=C1C(N(C3CCC(NC3=O)=O)C2=O)=O)=O
UNSPSC Code 12352101
NACRES NA.22

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Pomalidomide-PEG2-butyl iodide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 904724 Pomalidomide-PEG2-butyl iodide ≥95% 1835705-72-0 50MG $898 2026-04-30 Buy
BroadPharm bp-44910 Pomalidomide-amido-PEG2-buty iodide 1835705-72-0 5MG $130 2026-05-24 Buy
BroadPharm bp-44910 Pomalidomide-amido-PEG2-buty iodide 1835705-72-0 10MG $230 2026-05-24 Buy
BroadPharm bp-44910 Pomalidomide-amido-PEG2-buty iodide 1835705-72-0 25MG $420 2026-05-24 Buy
BroadPharm bp-44910 Pomalidomide-amido-PEG2-buty iodide 1835705-72-0 50MG $640 2026-05-24 Buy
Product number Packaging Price Buy
904724 50MG $898 Buy
bp-44910 5MG $130 Buy
bp-44910 10MG $230 Buy
bp-44910 25MG $420 Buy
bp-44910 50MG $640 Buy

Pomalidomide-PEG2-butyl iodide Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG2-butyl Iodide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant iodoalkane for reactivity with a nucleophilic group on a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant iodo group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reactivity: sulfuryl reactive
reagent type: ligand-linker conjugate

Pomalidomide-PEG2-butyl iodide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG2-butyl iodide Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4953 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1639 58
Changsha Bono New Materials Technology Co., Ltd. 18191076804 asherw9@hotmail.com China 2373 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9986 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9069 58
Supplier Advantage
HANGZHOU LEAP CHEM CO., LTD. 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Sigma-Aldrich 80
Shanghai YuanYe Biotechnology Co., Ltd. 60
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Changsha Bono New Materials Technology Co., Ltd. 58
Zhengzhou convergence chemical co., LTD 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58

View Lastest Price from Pomalidomide-PEG2-butyl iodide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-2-2-6-I pictures 2025-06-07 Pomalidomide-2-2-6-I
1835705-72-0
 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.

1835705-72-0(Pomalidomide-PEG2-butyl iodide)Related Search:

E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-CO2H Pomalidomide-PEG4-azide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 Pomalidomide-PEG1-azide POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-PEG2-N3 Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-piperazine BI 3663

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Pomalidomide-PEG2-butyl iodide Acetamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[2-[(6-iodohexyl)oxy]ethoxy]- Pomalidomide-2-2-6-I Crosslinker–E3 Ligase ligand conjugate, Pomalidomide-2-2-6-I, N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2-(2-((6-iodohexyl)oxy)ethoxy)acetamide, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-{2-[(6-iodohexyl)oxy]ethoxy}acetamide Pomalidomide-PEG2-butyl iodide N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[2-[(6-iodohexyl)oxy]ethoxy]acetamide 1835705-72-0 C23H28IN3O7