2-Amino-3-bromo-5-chloropyridine
- CAS No.
- 26163-03-1
- Chemical Name:
- 2-Amino-3-bromo-5-chloropyridine
- Synonyms
- 3-BROMO-5-CHLOROPYRIDIN-2-AMINE;oro-2-pyridinamine;2-Amino-3-bromo-5-chlorop;3-Bromo-5-chloropyrid-2-ylamine;3-BROMO-5-CHLORO-2-PYRIDINAMINE;2-AMINO-3-BROMO-5-CHLOROPYRIDINE;2-AMINO-5-CHLORO-3-BROMOPYRIDINE;2-Pyridinamine, 3-bromo-5-chloro-;2-Amino-3-bromo-5-chloropyridine98%;2-Amino-3-bromo-5-chloropyridine 98%
- CBNumber:
- CB7495355
- Molecular Formula:
- C5H4BrClN2
- Molecular Weight:
- 207.46
- MDL Number:
- MFCD00955627
- MOL File:
- 26163-03-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 82-83°C |
|---|---|
| Boiling point | 256.2±35.0 °C(Predicted) |
| Density | 1.834±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 1.91±0.49(Predicted) |
| form | Crystalline Powder |
| color | White to light brown |
| InChI | InChI=1S/C5H4BrClN2/c6-4-1-3(7)2-9-5(4)8/h1-2H,(H2,8,9) |
| InChIKey | UWGGGYYCKDCTGN-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(Cl)C=C1Br |
| CAS DataBase Reference | 26163-03-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H335-H315-H319 | |||||||||
| Precautionary statements | P280h-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-37/38-22-21/22 | |||||||||
| Safety Statements | 26-36/37/39-39-36/37 | |||||||||
| RIDADR | UN2811 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Amino-3-bromo-5-chloropyridine price More Price(74)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2402 | 2-Amino-3-bromo-5-chloropyridine >98.0%(GC) | 26163-03-1 | 5g | $40 | 2026-04-30 | Buy |
| TCI Chemical | A2402 | 2-Amino-3-bromo-5-chloropyridine >98.0%(GC) | 26163-03-1 | 25g | $123 | 2026-04-30 | Buy |
| Usbiological | 261234 | 2-Amino-3-bromo-5-chloropyridine Asreported | 26163-03-1 | 2g | $337 | 2026-06-03 | Buy |
| Usbiological | 261234 | 2-Amino-3-bromo-5-chloropyridine Asreported | 26163-03-1 | 5g | $552 | 2026-06-03 | Buy |
| Usbiological | 261234 | 2-Amino-3-bromo-5-chloropyridine Asreported | 26163-03-1 | 10g | $762 | 2026-06-03 | Buy |
2-Amino-3-bromo-5-chloropyridine Chemical Properties,Uses,Production
Uses
2-Amino-3-bromo-5-chloropyridine has a wide range of applications, including the synthesis of resins, surfactants, plastics, rubber, leather, papermaking, dyes, pharmaceuticals, pesticides, photographic film, explosives, building materials, and in disinfection, fumigation, and preservation processes. Furthermore, 2-amino-3-bromo-5-chloropyridine can be used as a basic organic chemical raw material and a high-quality fuel, primarily in the fields of fine chemicals and plastics.
Chemical Properties
Cream powder
Synthesis Reference(s)
Tetrahedron, 51, p. 8649, 1995 DOI: 10.1016/0040-4020(95)00478-Q
Synthesis
1072-98-6
26163-03-1
General procedure for the synthesis of 2-amino-3-bromo-5-chloropyridine from 2-amino-5-chloropyridine: In a 50L round bottom three-necked flask, a mixed solvent of DMF and ethanol (1:1.8 by volume, total 18.7L) was added, a thermometer and a reflux condenser were installed, and a magnetic stirrer was started. Sequentially, 4986.6 g of 2-amino-5-chloropyridine and 17336.3 g of N-bromosuccinimide were added, the temperature was raised to 85 °C and the reaction was stirred for 3.5 hours. The progress of the reaction was monitored by GC and TLC and after confirming the completion of the reaction, the solvent was removed using a rotary evaporator. The crude product obtained was recrystallized with hexane to give the pure 2-amino-3-bromo-5-chloropyridine. After drying, the calculated yield was 70.4% and purity was 99.15%.
References
[1] Patent: US2014/315888, 2014, A1. Location in patent: Paragraph 0620-0622
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961
[3] Patent: US2009/156603, 2009, A1. Location in patent: Page/Page column 46
[4] Patent: EP1202994, 2004, B1. Location in patent: Page 18
[5] European Journal of Medicinal Chemistry, 2018, vol. 157, p. 115 - 126
2-Amino-3-bromo-5-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Yuxiang Chemical Co., Ltd | 13809076511 | 344679571@qq.com | China | 311 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| SelectLab Chemicals GmbH | +49-(0)2383-919350 | info@selectlab.de | Germany | 393 | 55 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Lastest Price from 2-Amino-3-bromo-5-chloropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | 3-bromo-5-chloropyridin-2-amine
26163-03-1
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
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2026-08-20 | 2-Amino-3-bromo-5-chloropyridine
26163-03-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
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2019-07-06 | 2-Amino-3-bromo-5-chloropyridine
26163-03-1
|
$1.00 | 1KG | 98%-100% | 1 | Career Henan Chemical Co |
-

- 3-bromo-5-chloropyridin-2-amine
26163-03-1
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-

- 2-Amino-3-bromo-5-chloropyridine
26163-03-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 2-Amino-3-bromo-5-chloropyridine
26163-03-1
- $1.00
- 98%-100%
- Career Henan Chemical Co





