ChemicalBook >> CAS DataBase List >>Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg
- CAS No.
- 310427-94-2
- Chemical Name:
- Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg
- Synonyms
- β-Secretase Substrate IV, Fluorogenic;Arg-Glu(Edans)-(Asn670, Leu671)-Amyloidb/A4 Protei;ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG;Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg;H-ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG-OH;Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg;Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg;ARG-GLU(EDANS)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (668-675)-LYS (DABCYL)-ARG;Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg;ARG-GLU(EDANS)-[ASN670, LEU671]-AMYLOID B/A4 PROTEIN PRECURSOR 770 FRAGMENT 669-674-(DABCYL)LYS-ARG
- CBNumber:
- CB7679456
- Molecular Formula:
- C91H129N25O25S
- Molecular Weight:
- 2005.22
- MDL Number:
- MFCD03093396
- MOL File:
- 310427-94-2.mol
- TDS File:
- TDS
Last updated:2026-09-12 18:55:05
| Density | 1.463±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
|---|---|
| storage temp. | −20°C |
| solubility | DMSO: 5mg/mL |
| form | solid |
| pka | -0.260±0.40(predicted) |
| color | red |
| Sequence | Arg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 565758 | β-Secretase Substrate IV, Fluorogenic A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate, based on the EVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor | 310427-94-2 | 1 mg | $264 | 2026-04-30 | Buy |
| Biosynth | SFQ-3690-PI | H-Arg-Glu(Edans)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg-OH | 1mg | $486.88 | 2026-06-05 | Buy | |
| Biosynth | FA110960 | Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt | 310427-94-2 | 250ug | $315 | 2026-06-04 | Buy |
| Biosynth | FA110960 | Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt | 310427-94-2 | 500ug | $535 | 2026-06-04 | Buy |
| Biosynth | FA110960 | Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt | 310427-94-2 | 1000ug | $940 | 2026-06-04 | Buy |
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg Chemical Properties, Uses, Production
Uses
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].
Biological Activity
Cell permeable: no', 'Primary Target
β-secretase substrate', 'Product does not compete with ATP.', 'Reversible: no
References
[1] Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7. DOI:10.1016/j.bmcl.2011.03.023
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg Preparation Products And Raw materials
Raw materials
Preparation Products
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg Suppliers
Global Suppliers ( 38)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
310427-94-2 (Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg) Related Search:
ARG-GLU(EDANS)-[ASN670, LEU671]-AMYLOID B/A4 PROTEIN PRECURSOR 770 FRAGMENT 669-674-(DABCYL)LYS-ARG
ARG-GLU(EDANS)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (668-675)-LYS (DABCYL)-ARG
ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG
Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
H-ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG-OH
Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg
Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
L-Arginine, L-arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl-
L-Arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl-L-arginine
Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg
Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg
Arg-Glu(EDANS)-(Asn???,Leu??1)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Arg-Glu(EDANS)-(Asn???,Leu???)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
β-Secretase Substrate IV, Fluorogenic
Arg-Glu(Edans)-(Asn670, Leu671)-Amyloidb/A4 Protei
Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg
310427-94-2
C91H129N25O25S
Amyloid Precursor ProteinsNeuropeptides
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pro-beta-secretase (pro-memapsin 2)
pro-beta-secretase (pro-memapsin 2)Enzyme Substrates
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