ChemicalBook >> CAS DataBase List >>Formoterol

Formoterol

Formoterol structure

CAS No.: 73573-87-2

Chemical Name:: Formoterol

Synonyms: FORMOTEROL TARTRATE;Oxis;FORMOTEROL;Formoteral;Eformoterol;FormoterolBase;1-nitrotridec-1-ene;Formoterol Standard;FORMOTEROL TARTARATE;Formoterol USP/EP/BP

CBNumber:: CB7722411

Molecular Formula:: C19H24N2O4

Molecular Weight:: 344.41

MDL Number:: MFCD05662345

MOL File:: 73573-87-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:58:48

Request For Quotation

Formoterol Properties

Boiling point	603.2±55.0 °C(Predicted)
Density	1.233±0.06 g/cm3(Predicted)
solubility	DMSO: 20 mg/mL, soluble
form	solid
pka	8.95±0.50(Predicted)
color	off-white
Henry's Law Constant	1.1×10¹⁷ mol/(m³Pa) at 25℃, HSDB (2015)
Stability	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	73573-87-2(CAS DataBase Reference)
FDA UNII	5ZZ84GCW8B
ATC code	R03AC13

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H362-H361
Precautionary statements	P201-P260-P263-P264-P270-P308+P313-P201-P202-P281-P308+P313-P405-P501
WGK Germany	3
Hazardous Substances Data	73573-87-2(Hazardous Substances Data)

Formoterol price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	276694	Formoterol	73573-87-2	5mg	$336	2026-06-03	Buy
Usbiological	276694	Formoterol	73573-87-2	10mg	$472	2026-06-03	Buy
Usbiological	276694	Formoterol	73573-87-2	25mg	$755	2026-06-03	Buy
Usbiological	276694	Formoterol	73573-87-2	50mg	$1194	2026-06-03	Buy
Biosynth	FF35161	Formoterol	73573-87-2	25mg	$236.5	2026-06-04	Buy

Product number	Packaging	Price	Buy
276694	5mg	$336	Buy
276694	10mg	$472	Buy
276694	25mg	$755	Buy
276694	50mg	$1194	Buy
FF35161	25mg	$236.5	Buy

Formoterol Chemical Properties, Uses, Production

Description

Formoterol is a potent bronchoselective β-agonist with long duration of action given by inhalation.

Chemical Properties

solid

Uses

Labeled Formoterol, intended for use as an internal standard for the quantification of Formoterol by GC- or LC-mass spectrometry.

Uses

Formoterol is a useful compound for treating respiratory obstructive diseases.

Definition

ChEBI: A phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent.

brand name

Foradil (Novartis).

General Description

Formoterol (Foradil) isalso a lipophilic (log P= 1.6) and long-acting β2-agonist. Ithas 3'-formylamino ( β-directing) and 4 OH groups on onephenyl ring and a lipophilic -directing N-isopropyl-pmethoxyphenylgroup on the nitrogen atom. Its long DOA(12 hours), which is comparable to that of salmeterol, hasbeen suggested to result from its association with the membranelipid bilayer, from which it gradually diffuses to provideprolonged stimulation of β2 receptors and its resistanceto MAO and COMT. Formoterol has a much faster onset ofaction than does salmeterol as result of its lower lipophilicity.Both of these long-acting drugs are used by inhalationand are recommended for maintenance treatment of asthma,usually in conjunction with an inhaled corticosteroid.

Mechanism of action

Formoterol has 3′-formylamino and 4′-hydroxy ring R3 substitution pattern but also an alkoxyphenylethyl lipophilic group R1 on the nitrogen, similar to ritodrine. Although it is less lipophilic (log P = 1.6) than salmeterol, it has a 12-hour duration of action similar to that for salmeterol. It is administered as an inhaled dry powder, because it is unstable to heat and moisture. It is a mixture of (R,R)-(–)- and (S,S)-(+)-stereoisomers, with the (R,R)-isomer having approximately 1,000-fold more affinity for the β2-receptor than the (S,S)-isomer. Because of its high potency and low dose, however, there is no clinical advantage for using (R,R)-formoterol as bronchodilator compared to the racemate. Unlike salmeterol, formoterol has a faster onset of action as a result of its lower lipophilicity. It is also more potent; a 12-μg dose of formoterol has been demonstrated to be equivalent to a 50-μg dose of salmeterol.

Formoterol Preparation Products And Raw materials

Raw materials

FORMOTEROL INTERMEDIATE Benzenemethanol, 3-amino-α-[[[(1R)-2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-, (αR)- 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone (R)-1-(4-Benzyloxy-3-nitrophenyl)-2-bromoethanol 1316100-17-0

1-(4-Methoxyphenyl)-2-nitropropene (R)-N-(2-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)phenyl)formamide Oxirane, [3-nitro-4-(phenylMethoxy)phenyl]-, (2R)- 4-Benzyloxy-3-nitroacetophenone Formoterol Impurity

N-(2-(benzyloxy)-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide 2-(Benzylamino)-1-(4-methoxyphenyl)-propane (R)-(-)-1-(4'-methoxyphenyl)-2-benzylaminopropane 4-Methoxyphenylacetone

1of3

Preparation Products

Formoterol Suppliers

Global Suppliers ( 110)

Supplier	Tel	Email	Country	ProdList	Advantage
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2110	70
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9643	60
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4765	58
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12323	58
The future of Shanghai Industrial Co., Ltd.	021-61552785	sales@shshiji.com	China	9531	55
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810 18652991625	sales@sunlidabio.com	China	3223	55
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2774	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58

Supplier	Advantage
Pure Chemistry Scientific Inc.	62
Adamas Reagent, Ltd.	59
LGM Pharma	70
Spectrum Chemical Manufacturing Corp.	60
Dalian Meilun Biotech Co., Ltd.	58
Beijing HuaMeiHuLiBiological Chemical	58
The future of Shanghai Industrial Co., Ltd.	55
Nanjing Sunlida Biological Technology Co., Ltd.	55
AdooQ BioScience, LLC	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58

View Latest Price from Formoterol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	N-[2-Hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide 73573-87-2	$1.00	1kg	99%		Career Henan Chemical Co

N-[2-Hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
73573-87-2
$1.00
99%
Career Henan Chemical Co

73573-87-2 (Formoterol) Related Search:

(N,O-DIBENZYLATED) FORMOTEROL FUMARATE, 98% ( FOR FORMOTEROL FUMARATE ),N,O-DIBENZYLATED FORMOTEROL FUMARATE,n,o-dibenzylated formoterol Formoterol fumarate dihydrate Formoterol fumarate Formoterol Formoterol Intermediate

Formamide Arformoterol tartrate (R,R)-Formoterol FORMOTEROL-D6 Formoterol for impurity I identification

FORMOTEROL FUMARATE FOR SYSTEM SUITABILITY FORMOTEROL-D3 (S,S)-Formoterol FORMOTEROL FUMARATE DIHYDRATE ( N, O Cdiphenzylated) Formoterol Fumarate

Formoterol·fumaric acid FORMOTEROL FUMARATE DIHYDRATE FOR IMPURITY I IDENTIFICATION (N,O-Dibenzylate) formoterol fumanate

1of4

n-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide FORMOTEROL TARTARATE FormoterolBase Eformoterol Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, rel- Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)-(+-)- Oxis N-[2-Hydroxy-5-[1(R)-hydroxy-2-[[2-(4-methoxyphenyl)-1(R)-methylethyl] amino]ethyl]phenyl]formamide FORMOTEROL TARTRATE FORMOTEROL rel-N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide 1-nitrotridec-1-ene Formoterol USP/EP/BP Formoterol (10mM in DMSO) Formoteral Formoterol Standard 73573-87-2 C19H24N2O4 Other APIs Inhibitors (intermediates of formoterol ) API