GALNON
- CAS No.
- 475115-35-6
- Chemical Name:
- GALNON
- Synonyms
- GALNON;FMoc-Cha-Lys-AMC;Galnon, Fmoc-Cha-Lys-AMC;FMoc-b-cyclohexyl-Ala-Lys-AMC;FMOC-BETA-CYCLOHEXYL-ALA-LYS-AMC;3-CYCLOHEXYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-ALANYL-N-(4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL)-L-LYSINAMIDE;L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
- CBNumber:
- CB7740387
- Molecular Formula:
- C40H46N4O6
- Molecular Weight:
- 678.82
- MDL Number:
- MFCD06198924
- MOL File:
- 475115-35-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 937.5±65.0 °C(Predicted) |
|---|---|
| Density | 1.242±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: insoluble |
| form | solid |
| pka | 10.68±0.46(Predicted) |
| color | white |
| FDA UNII | NK59Y4NQ33 |
GALNON price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 255352 | Galnon Asreported | 475115-35-6 | 10mg | $389 | 2026-06-03 | Buy |
| Biosynth | FG111343 | Galnon trifluoroacetate salt | 475115-35-6 | 100mg | $900 | 2026-06-04 | Buy |
| Biosynth | FG111343 | Galnon trifluoroacetate salt | 475115-35-6 | 50mg | $900 | 2026-06-04 | Buy |
| Biosynth | FG111343 | Galnon trifluoroacetate salt | 475115-35-6 | 25mg | $900 | 2026-06-04 | Buy |
| Biosynth | FG111343 | Galnon trifluoroacetate salt | 475115-35-6 | 250mg | $1645 | 2026-06-04 | Buy |
GALNON Chemical Properties, Uses, Production
Uses
Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].
Biological Activity
Novel non-peptide galanin GAL 1 receptor agonist (K i = 4.8 μ M). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo ; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.
References
[1] Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. DOI:10.1073/pnas.0403802101
[2] Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20. DOI:10.1016/j.npep.2007.05.001
GALNON Preparation Products And Raw materials
Raw materials
Preparation Products
GALNON Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| HangZhou YuHao Chemical Technology Co., Ltd. | 0571-82693216 | info@yuhaochemical.com | China | 1999 | 58 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
