1,2-Cyclohexanedione
- CAS No.
- 765-87-7
- Chemical Name:
- 1,2-Cyclohexanedione
- Synonyms
- Cyclohexane-1,2-dione;1,2-CYCLOHEXANDIONE;Cyclohexane-1,2-dione 98%;1,2-CycL;AKOS 197;AI3-25042;NSC 32950;CCRIS 6296;BRN 0507419;DIHYDROCATECHOL
- CBNumber:
- CB7854271
- Molecular Formula:
- C6H8O2
- Molecular Weight:
- 112.13
- MDL Number:
- MFCD00001648
- MOL File:
- 765-87-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 34-38 °C (lit.) |
|---|---|
| Boiling point | 193-195 °C (lit.) |
| Density | 1,118 g/cm3 |
| refractive index | 1.518-1.52 |
| FEMA | 3458 | 2-HYDROXY-2-CYCLOHEXEN-1-ONE |
| Flash point | 184 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| form | Liquid After Melting |
| color | Clear yellow |
| Odor | at 10.00 % in dipropylene glycol. sweet acorn nut skin maple caramel brothy |
| Odor Type | nutty |
| Water Solubility | Soluble |
| JECFA Number | 424 |
| BRN | 507419 |
| InChI | 1S/C6H8O2/c7-5-3-1-2-4-6(5)8/h1-4H2 |
| InChIKey | OILAIQUEIWYQPH-UHFFFAOYSA-N |
| SMILES | O=C1CCCCC1=O |
| LogP | 0.252 (est) |
| CAS DataBase Reference | 765-87-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 75C1OVW0FJ |
| NIST Chemistry Reference | c-hexane-1,2-dione(765-87-7) |
| EPA Substance Registry System | 1,2-Cyclohexanedione (765-87-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P271-P280 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GV0340000 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29142990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
1,2-Cyclohexanedione price More Price(93)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C101400 | 1,2-Cyclohexanedione 97% | 765-87-7 | 1g | $55.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | C101400 | 1,2-Cyclohexanedione 97% | 765-87-7 | 5g | $122 | 2026-04-30 | Buy |
| TCI Chemical | C0728 | 1,2-Cyclohexanedione >97.0%(GC) | 765-87-7 | 5g | $73 | 2026-04-30 | Buy |
| TCI Chemical | C0728 | 1,2-Cyclohexanedione >97.0%(GC) | 765-87-7 | 25g | $288 | 2026-04-30 | Buy |
| Usbiological | 267766 | Cyclohexane-1,2-dione Asreported | 765-87-7 | 5g | $319 | 2026-06-03 | Buy |
1,2-Cyclohexanedione Chemical Properties, Uses, Production
Chemical Properties
clear yellow liquid after melting
Uses
1,2-Cyclohexanedione have been used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds.
Uses
1,2-Cyclohexanedione is utilized as a substrate to study enzyme cyclohexane-1,2-dione hydrolase, which is a new tool to degrade alicyclic compounds. It also acts as a specific reagent for arginine residues.
Definition
ChEBI: Cyclohexane-1,2-dione is a cyclohexanedione carrying oxo substituents at positions 1 and 2.
Reactions
1,2-Cyclohexanedione may effectively occupy vacant coordination sites and thus promote the present cycloisomerization[1]. Tanaka et al. research the catalytic cycloisomerization of 1,6- and 1,7-diynes leading to trienes and vinylpyrroles by using a cationic rhodium(I)/Segphos complex (2.5-10 mol %) and 1,2-cyclohexanedione (100 mol %).
Synthesis Reference(s)
Journal of the American Chemical Society, 73, p. 4658, 1951 DOI: 10.1021/ja01154a048
Tetrahedron Letters, 25, p. 603, 1984 DOI: 10.1016/S0040-4039(00)99949-0
The Journal of Organic Chemistry, 39, p. 3295, 1974 DOI: 10.1021/jo00936a034
References
[1] Ken Tanaka, Masao Hirano, Yousuke Otake. “Cationic Rhodium(I)/Segphos-Catalyzed Cycloisomerization of 1,6- and 1,7-Diynes in the Presence of 1,2-Cyclohexanedione.” Organic Letters 9 20 (2007): 3953–3956.
1,2-Cyclohexanedione Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Milestone Chemical Wuxi Co.,Ltd | 18068271528 | 1917265470@qq.com | China | 72 | 58 |
| Suzhou ChonTech Biopharma Co.,Ltd | 0512-63101022 13912623614 | sales@chontech.com | Austria | 220 | 58 |
| Xiamen Ruiyuxin Biotechnology Co., Ltd | 0598-5501589 15392323620 | zmy@welikepharma.com | China | 97 | 58 |
| Sanover (Xiamen) Technology Co., Ltd | 请加微信(同手机号)或QQ询价 13876246362 | 422165847@qq.com | China | 500 | 58 |
| Suzhou chems bio-tech.co.,Ltd. | 0512-67903504 13814824891;13814824891 | 604360797@qq.com | China | 409 | 58 |
| Hangzhou Yanding Biomedical Technology Co., Ltd. | 18989469219 | 56560759@qq.com | China | 395 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from 1,2-Cyclohexanedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 1,2-Cyclohexanedione
765-87-7
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2023-05-23 | 1,2-Cyclohexanedione
765-87-7
|
1kg | 98% | 1MT | Jiangsu Nata Opto-electronic Material Co.,Ltd. | ||
 |
2023-03-21 | 1,2-Cyclohexanedione
765-87-7
|
1kg T | 96%MIN | 20TONS | Milestone Chemical Wuxi Co.,Ltd |
-
- 1,2-Cyclohexanedione
765-87-7
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1,2-Cyclohexanedione
765-87-7
- 98%
- Jiangsu Nata Opto-electronic Material Co.,Ltd.
-
- 1,2-Cyclohexanedione
765-87-7
- 96%MIN
- Milestone Chemical Wuxi Co.,Ltd
