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1,4-Cyclohexanedione

1,4-Cyclohexanedione structure

CAS No.: 637-88-7

Chemical Name:: 1,4-Cyclohexanedione

Synonyms: CHD;Cyclohexane-1,4-dione;CYCLOHEXANEDIONE;1,4-Cyclohexadione;Tetrahydroquinone;1,4-CYCHEXANEDIONE;1,4-CYCLOHEXANDIONE;1,4-cyclohexanedion;Cyclohexan-1,4-dione;1,4-Dioxocyclohexane

CBNumber:: CB7138205

Molecular Formula:: C6H8O2

Molecular Weight:: 112.13

MDL Number:: MFCD00001606

MOL File:: 637-88-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:24:38

Product description	Number	Pack Size	Price
1,4-Cyclohexanedione 98%	125423	10g	$66.4
1,4-Cyclohexanedione 98%	125423	50g	$122
1,4-Cyclohexanedione >98.0%(GC)	C0730	25g	$47
1,4-Cyclohexanedione >98.0%(GC)	C0730	500g	$458
1,4-Cyclohexanedione	C987990	100g	$275
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1,4-Cyclohexanedione Properties

Melting point	77-78.5 °C (lit.)
Boiling point	112 °C (19.5026 mmHg)
Density	1.0861
refractive index	1.4570 (estimate)
Flash point	132 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in methanol and ethanol.
form	Crystalline Powder or Flakes
color	Light yellow to yellow or beige
BRN	774152
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
InChI	1S/C6H8O2/c7-5-1-2-6(8)4-3-5/h1-4H2
InChIKey	DCZFGQYXRKMVFG-UHFFFAOYSA-N
SMILES	O=C1CCC(=O)CC1
LogP	-0.910 (est)
CAS DataBase Reference	637-88-7(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	BJS27Z99AM
NIST Chemistry Reference	1,4-Cyclohexanedione(637-88-7)
EPA Substance Registry System	1,4-Cyclohexanedione (637-88-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Safety Statements

22-24/25

WGK Germany

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29142900

Storage Class

11 - Combustible Solids

NFPA 704

	1
1		0

1,4-Cyclohexanedione price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	125423	1,4-Cyclohexanedione 98%	637-88-7	10g	$66.4	2026-03-19	Buy
Sigma-Aldrich	125423	1,4-Cyclohexanedione 98%	637-88-7	50g	$122	2026-03-19	Buy
TCI Chemical	C0730	1,4-Cyclohexanedione >98.0%(GC)	637-88-7	25g	$47	2026-03-19	Buy
TCI Chemical	C0730	1,4-Cyclohexanedione >98.0%(GC)	637-88-7	500g	$458	2026-03-19	Buy
TRC	C987990	1,4-Cyclohexanedione	637-88-7	100g	$275	2021-12-16	Buy

Product number	Packaging	Price	Buy
125423	10g	$66.4	Buy
125423	50g	$122	Buy
C0730	25g	$47	Buy
C0730	500g	$458	Buy
C987990	100g	$275	Buy

1,4-Cyclohexanedione Chemical Properties,Uses,Production

Chemical Properties

tan or yellow crystalline powder

Uses

1,4-Cyclohexanedione is used in the preparation of 1,4 benzoquinone and bromoorganics. It is also used to study the influence of visible light on the bromate-1,4-cyclohexanedione-ferroin oscillating reaction. It plays a vital role in pharmaceuticals, plant growth regulator and as a conducting material.

Definition

ChEBI: 1,4-Cyclohexanedione is a cyclohexanedione with oxo substituents at positions 1 and 4.

Preparation

Synthesis of 1,4-cyclohexanedione: put diethyl succinylsuccinate into a flask, add a mixture of concentrated sulfuric acid, water and ethanol, reflux in oil solution for 5 days, cool, and neutralize to pH with ammonia water = 8; then extract 4 times with chloroform, and recover the chloroform to obtain the crude product; then the crude product is subjected to vacuum distillation, and the distillate is poured into cold petroleum ether, filtered, and air-dried to obtain 1,4-cyclohexanedi Ketone Products.

Synthesis Reference(s)

Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377

General Description

1,4-Cyclohexanedione(CHD) undergoes uncatalyzed oscillatory reactions during oxidation by acidic bromate in nitric acid and sulphuric acid solution. It reacts with acidic bromate to form 1,4-dihydroxybenzene which on further oxidation and bromination yields 1,4-benzoquinone and bromoorganics.

Pharmacology

The cyclohexanedione (CHD) herbicides inhibit fatty acid synthesis in plants by interfering with the activity of the enzyme Acetyl-Coenzyme A Carboxylase (ACCase). ACCase-inhibiting herbicides provide excellent control of grass weeds in dicotyledonous and some grass crops. A less-sensitive ACCase mediates the intrinsic resistance of dicotyledonous plants to the AOPP and CHD herbicides (34,35). Although grasses are target species of this group of herbicides, not all are equally affected, and sensitivity differences can occur between varieties or even within a genus.

1,4-Cyclohexanedione synthesis

Synthesis of 1,4-Cyclohexanedione from Cyclohexanol

1,4-Cyclohexanedione Preparation Products And Raw materials

Raw materials

dilute sulphuric acid Diethyl succinosuccinate Diethyl succinate 1,4-Dioxaspiro[4.5]decan-8-one 1,4-Cyclohexanedione bis(ethylene ketal)

1,4-DIOXA-SPIRO[4.5]DECAN-8-OL

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Preparation Products

HOMOGENTISIC ACID GAMMA-LACTONE trans-1,4-Diaminocyclohexane trans-4-Aminocyclohexanol Pentacene N-Methoxy-N-methylacetamide

1,4-Cyclohexanediol 1,2-Cyclohexanediol 4-HYDROXYCYCLOHEXANONE Mecarbinate 2-Methyl-1,3-cyclopentanedione

1 4-BIS(DIPHENYLAMINO)BENZENE 10-Phenyl-10H-phenothiazine 4-Methoxycyclohexanol 5,7-Dihydro-indolo[2,3-b]carbazole

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1,4-Cyclohexanedione Suppliers

Global( 425)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Yuanda Chemical Co., Ltd	28-85356300 +8618980937689	sales@ydachem.com	CHINA	94	58
Shanghai Bojing Chemical Co.,Ltd.	+86-86-02137122233 +8613795318958	bj1@bj-chem.com	China	299	55
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13815	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
Jiangsu Qingquan Chemical Co., Ltd.	+86-571-86589381,86589382,86589383	sales1@qqpharm.com	CHINA	154	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29822	58

Supplier	Advantage
Chengdu Yuanda Chemical Co., Ltd	58
Shanghai Bojing Chemical Co.,Ltd.	55
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Jiangsu Qingquan Chemical Co., Ltd.	55
career henan chemical co	58

View Lastest Price from 1,4-Cyclohexanedione manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	1,4-Cyclohexanedione 637-88-7	US $0.00 / KG	1KG	99%	100 MT	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-27	1,4-Cyclohexanedione 637-88-7	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-20	1,4-Cyclohexanedione 637-88-7	US $40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.

1,4-Cyclohexanedione
637-88-7
US $0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

1,4-Cyclohexanedione
637-88-7
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

1,4-Cyclohexanedione
637-88-7
US $40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

1,4-Cyclohexanedione Spectrum

1,4-Cyclohexanedione(637-88-7)MS 1,4-Cyclohexanedione(637-88-7)¹HNMR 1,4-Cyclohexanedione(637-88-7)¹³CNMR 1,4-Cyclohexanedione(637-88-7)IR1 1,4-Cyclohexanedione(637-88-7)IR2 1,4-Cyclohexanedione(637-88-7)Raman

637-88-7(1,4-Cyclohexanedione )Related Search:

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DIETHYL 2,5-DIOXOBICYCLO[2.2.2]OCTANE-1,4-DICARBOXYLATE 1,2-Cyclohexanedione 5-(2-ETHYLTHIO PROPYL)-1,3-CYCLOHEXANEDIONE 5-PHENYLCYCLOHEXANE-1,3-DIONE 4,4-DIMETHYL-1,3-CYCLOHEXANEDIONE

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1,4-Dioxocyclohexane Tetrahydroquinone TETRAHYDRO-P-BENZOQUINONE Cyclohexan-1,4-dione 98% 1,4-CYCHEXANEDIONE Cyclohexan-1,4-dione 1,4-Cyclohexanedione,98% 1,4-CYCLOHEXANDIONE 1,4-TETRAHYDROQUINONE CYCLOHEXANEDIONE 1,4-CYCLOHEXANEDIONE, 98%1,4-CYCLOHEXANEDIONE, 98%1,4-CYCLOHEXANEDIONE, 98% 1,4-Cyclohexanedione 1,4-Cyclohexanedione, 98% 10GR 1,4-Cyclohexanedione, 98% 50GR 1,4-Cyclohexadione 1,4-CYCLOHEXANEDIONE FOR SYNTHESIS 1,4-cyclohexanedion 1,4-Cyclohexanedione Vetec(TM) reagent grade, 98% 1, 4 - ring adipic ketone 1,4-Cyclohexanedione > 637-88-7 1,4-Cyclohexanedione 1,4-Cyclohexanedione pure, 99% 1,4-Cyclohexanedione (8CI, 9CI, ACI) Cyclohexane-1,4-dione CHD 637-88-7 C3 to C6 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks C3 to C6 Carbonyl Compounds Ketones Building Blocks C3 to C6 Carbonyl Compounds Chemical Synthesis Organic Building Blocks fine chemicals ketone Pharmaceutical Intermediate