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ChemicalBook >> CAS DataBase List >>(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Structure
(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile structure
CAS No.
38321-02-7
Chemical Name:
(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile
Synonyms
d-Verapamil;Dexverapami;Dexverapamil;Dexverapamil Hydrochloride;[R,(+)]-2-(3,4-Dimethoxyphenyl)-2-isopropyl-5-(N-methyl-3,4-dimethoxyphenethylamino)valeronitrile;(R)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile;(αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (R)-;Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, (αR)-
CBNumber:
CB7941337
Molecular Formula:
C27H38N2O4
Molecular Weight:
454.61
MDL Number:
MFCD00864679
MOL File:
38321-02-7.mol
MSDS File:
SDS
Last updated:2026-05-11 15:21:01
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(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Properties

Melting point 129-131°C
Boiling point 586.1±50.0 °C(Predicted)
Density 1.058±0.06 g/cm3(Predicted)
pka 8.97±0.50(Predicted)
FDA UNII QR5PYD126V
NCI Drug Dictionary dexverapamil

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological V2121-49 (R)-(+)-Verapamil Hydrochloride ≥90% 38321-02-7 1mg $531 2026-06-04 Buy
American Custom Chemicals Corporation API0000091 R(+)-VERAPAMIL 95.00% 38321-02-7 1MG $757.97 2021-12-16 Buy
American Custom Chemicals Corporation API0000091 R(+)-VERAPAMIL 95.00% 38321-02-7 10MG $2243.59 2021-12-16 Buy
Medical Isotopes, Inc. 14156 (R)-(+)-VerapamilHCl 38321-02-7 5mg $2400 2021-12-16 Buy
Product number Packaging Price Buy
V2121-49 1mg $531 Buy
API0000091 1MG $757.97 Buy
API0000091 10MG $2243.59 Buy
14156 5mg $2400 Buy

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells

Definition

ChEBI: A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby p tentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil.

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile synthesis

3490-06-0
38176-01-1
38321-02-7
Synthesis of (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile from N-Methylhomoveratrylamine and Benzeneacetonitrile, α-(3-chloropropyl)-3,4-dimethoxy-α-(1-methylethyl)-, (αR)-

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
QUALITY CONTROL SOLUTIONS LTD. +86-0755-66853366 +86-13670046396 export03@qcsrm.com China 24318 58
Guangzhou Austine Biotechnology Co., LTD 15918640830 13268843209 1947181658@qq.com China 9032 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Hubei Rhema Reference Materials Technology Co., Ltd. 15787879035 15787875101 ydw9035@rmastandards.com China 9997 58
DAYANG CHEM (HANGZHOU) CO.,LTD +86-88938639 +86-17705817739 info@dycnchem.com China 53799 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
LGM Pharma 70
Clearsynth Labs Limited 58
Guangzhou Younan Technology Co., Ltd 58
Energy Chemical 58
QUALITY CONTROL SOLUTIONS LTD. 58
Guangzhou Austine Biotechnology Co., LTD 58
TargetMol Chemicals Inc. 58
Hubei Rhema Reference Materials Technology Co., Ltd. 58
DAYANG CHEM (HANGZHOU) CO.,LTD 58
TargetMol Chemicals Inc. 58

View Lastest Price from (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dexverapamil pictures 2026-05-11 Dexverapamil
38321-02-7
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • Dexverapamil pictures
  • Dexverapamil
    38321-02-7
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

38321-02-7((+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile)Related Search:

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 2-(4-Methoxyphenyl)-2-methylpropanenitrile Devapamil (+/-)-Verapamil hydrochloride METHOXY-(-)-VERAPAMIL HYDROCHLORIDE
R(+)-VERAPAMIL HYDROCHLORIDE 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile 4-HYDROXY-3-METHOXYPHENYLACETONITRILE Verapamil (3,4-Dimethoxyphenyl)acetonitrile
Benzeneacetonitrile Valeronitrile P-O-DESMETHYL VERAPAMIL 1-(3,4-DIMETHOXYPHENYL)-VALERONITRILE NORVERAPAMIL
Emopamil 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE 2-(4-HYDROXYPHENYL)-2-METHYLPROPANENITRILE

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Dexverapamil (aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile Dexverapami Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (aR)- (9CI) Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (R)- d-Verapamil (aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile Hydrochloride Dexverapamil Hydrochloride (R)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile [R,(+)]-2-(3,4-Dimethoxyphenyl)-2-isopropyl-5-(N-methyl-3,4-dimethoxyphenethylamino)valeronitrile Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, (αR)- 38321-02-7 C27H39ClN2O4 Intermediates & Fine Chemicals Pharmaceuticals