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9-Chloroacridine

9-Chloroacridine Structure
9-Chloroacridine structure
CAS No.
1207-69-8
Chemical Name:
9-Chloroacridine
Synonyms
AURORA KA-4303;9-chloracridine;9-chloroacridone;9-CHLOROACRIDINE;Acridine, 9-chloro-;9-Chloroacridine,95%;9-CHLOROACRIDINE 95%;9-Chloroacridine, GC 95%;9-Chloroacridine/9-Chloroacridine
CBNumber:
CB8106496
Molecular Formula:
C13H8ClN
Molecular Weight:
213.66
MDL Number:
MFCD00022266
MOL File:
1207-69-8.mol
MSDS File:
SDS
Last updated:2026-05-28 02:51:02
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9-Chloroacridine Properties

Melting point 116-120 °C (lit.)
Boiling point 346.74°C (rough estimate)
Density 1.1961 (rough estimate)
refractive index 1.5868 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form solid
pka 3.96±0.10(Predicted)
Appearance Light yellow to yellow Solid
InChI InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
InChIKey BPXINCHFOLVVSG-UHFFFAOYSA-N
SMILES C1C2C(=NC3C(C=2Cl)=CC=CC=3)C=CC=1
CAS DataBase Reference 1207-69-8(CAS DataBase Reference)
NIST Chemistry Reference Acridine, 9-chloro-(1207-69-8)
EPA Substance Registry System Acridine, 9-chloro- (1207-69-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
RIDADR  UN2811
WGK Germany  3
TSCA  TSCA listed
HS Code  29379000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

9-Chloroacridine price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 159425 9-Chloroacridine 97% 1207-69-8 1g $66.4 2026-04-30 Buy
Sigma-Aldrich 159425 9-Chloroacridine 97% 1207-69-8 5g $296 2026-04-30 Buy
TCI Chemical C0392 9-Chloroacridine min. 95.0 % 1207-69-8 1G $49 2026-04-30 Buy
TCI Chemical C0392 9-Chloroacridine min. 95.0 % 1207-69-8 5G $196 2026-04-30 Buy
Activate Scientific AS49371 9-Chloroacridine 97% 1207-69-8 1g $31 2026-06-04 Buy
Product number Packaging Price Buy
159425 1g $66.4 Buy
159425 5g $296 Buy
C0392 1G $49 Buy
C0392 5G $196 Buy
AS49371 1g $31 Buy

9-Chloroacridine Chemical Properties,Uses,Production

Chemical Properties

Green to brown solid

Uses

9-Chloroacridine was employed as chromogenic reagent in the spectrophotometric method for the quantitative determination of dapsone. It was also used in the synthesis of:
series of novel chalcones bearing acridine moiety attached to the amino group in their ring A
new acridine derivatives
9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives

Synthesis

9(10H)-ACRIDONE

578-95-0

9-Chloroacridine

1207-69-8

The general procedure for the synthesis of 9-chloroacridine from acridinone was as follows: 9-acridinone (4.01 g, 21 mmol) was dissolved in phosphoryl chloride (105 mL, 1.13 mol), a magnetic stirrer was added, and the reaction was carried out at reflux for 12 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, slowly poured into crushed ice (650 g) and the pH was adjusted to a weak base with concentrated ammonium hydroxide. The resulting light brown solid was collected by filtration, washed well with water and subsequently dried in air for 24 hours. Purification by fast column chromatography (silica gel as stationary phase, eluent was a solvent mixture of 75% hexane, 20% THF and 5% triethylamine) gave 3.97 g (89% yield) of the target product, 9-chloroacridine, as fine yellow needle-like crystals. The obtained product was confirmed to be consistent with the sample prepared by Method A by TLC, melting point determination and spectral data analysis.

References

[1] Pharmaceutical Sciences, 1997, vol. 3, # 5-6, p. 235 - 239
[2] European Journal of Inorganic Chemistry, 1999, # 3, p. 557 - 563
[3] Heterocycles, 2014, vol. 88, # 1, p. 535 - 546
[4] Patent: CN108640873, 2018, A. Location in patent: Paragraph 0022; 0023
[5] Chemical Biology and Drug Design, 2017, vol. 90, # 5, p. 926 - 935

9-Chloroacridine synthesis

110166-26-2
1207-69-8
Synthesis of 9-Chloroacridine from 9(10H)-Acridinimine

9-Chloroacridine Preparation Products And Raw materials

Raw materials

10H-acridine-9-thione Acridine Aniline 9(10H)-ACRIDONE 2-Chlorobenzoic acid
N-Phenylanthranilic acid Benzoic acid 2-Bromobenzoic acid

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Preparation Products

Amsacrine 9-Aminoacridine 9-(Bromomethyl)acridine 9-Phenylacridine 9-BroMoacridine

9-Chloroacridine Suppliers

Global( 236)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Yuanli Biological Technology Co., Ltd. 0371-67897870 18339906974 2130541246@qq.com China 111 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
ShengXiong Biological Technology Development Co., Ltd. 86-021-64960112 13774219177 alpha9196@gmail.com China 52 65
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
Zhengzhou Yuanli Biological Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Jia Xing Isenchem Co.,Ltd 66
ShengXiong Biological Technology Development Co., Ltd. 65
Shanghai Hanhong Scientific Co.,Ltd. 64

View Lastest Price from 9-Chloroacridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
9-Chloroacridine pictures 2026-09-11 9-Chloroacridine
1207-69-8
 $44.00-296.00 5g 0.98 25kg Shanghai UCHEM Inc.
9-Chloroacridine pictures 2026-05-18 9-Chloroacridine
1207-69-8
 1kg 98% Hefei Lbao Physical & Chemical Science Co.,Ltd
9-Chloroacridine pictures 2025-06-27 9-Chloroacridine
1207-69-8
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
  • 9-Chloroacridine pictures
  • 9-Chloroacridine
    1207-69-8
  • $0.00
  • 98%
  • Hefei Lbao Physical & Chemical Science Co.,Ltd

9-Chloroacridine Spectrum

9-Chloroacridine(1207-69-8)1HNMR9-Chloroacridine(1207-69-8)IR19-Chloroacridine(1207-69-8)ESR

1207-69-8(9-Chloroacridine)Related Search:

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9-CHLOROACRIDINE AURORA KA-4303 9-Chloroacridine, GC 95% 9-CHLOROACRIDINE 95% 9-Chloroacridine,95% 9-chloroacridone Acridine, 9-chloro- 9-chloracridine 9-Chloroacridine/9-Chloroacridine 1207-69-8 C13H8ClN Acridines Building Blocks Heterocyclic Building Blocks Acridines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks AcridinesHeterocyclic Building Blocks Pharmaceutical material and intermeidates 1207-69-8