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5-METHOXY-2-METHYLINDOLE

CAS No.
1076-74-0
Chemical Name:
5-METHOXY-2-METHYLINDOLE
Synonyms
NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-METHOXY-2-METHYLINDOLE;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
CBNumber:
CB8174569
Molecular Formula:
C10H11NO
Molecular Weight:
161.2
MDL Number:
MFCD00005620
MOL File:
1076-74-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:43:44
Product description Number Pack Size Price
5-Methoxy-2-methylindole 99% M15451 1g $57.5
5-Methoxy-2-methylindole 99% M15451 5g $191
5-Methoxy-2-methylindole >99.0%(GC) M0730 1g $118
5-Methoxy-2-methylindole >99.0%(GC) M0730 5g $467
5-Methoxy-2-methylindole 234261 1g $170
More product size

5-METHOXY-2-METHYLINDOLE Properties

Melting point 86-88 °C (lit.)
Boiling point 145 °C / 1.5mmHg
Density 1.0840 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol (very faint turbidity.)
form Crystalline Powder or Crystals
pka 17.28±0.30(Predicted)
color White to light beige
InChI InChI=1S/C10H11NO/c1-7-5-8-6-9(12-2)3-4-10(8)11-7/h3-6,11H,1-2H3
InChIKey VSWGLJOQFUMFOQ-UHFFFAOYSA-N
SMILES N1C2=C(C=C(OC)C=C2)C=C1C
CAS DataBase Reference 1076-74-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

5-METHOXY-2-METHYLINDOLE price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M15451 5-Methoxy-2-methylindole 99% 1076-74-0 1g $57.5 2026-04-30 Buy
Sigma-Aldrich M15451 5-Methoxy-2-methylindole 99% 1076-74-0 5g $191 2026-04-30 Buy
TCI Chemical M0730 5-Methoxy-2-methylindole >99.0%(GC) 1076-74-0 1g $118 2026-04-30 Buy
TCI Chemical M0730 5-Methoxy-2-methylindole >99.0%(GC) 1076-74-0 5g $467 2026-04-30 Buy
Usbiological 234261 5-Methoxy-2-methylindole 1076-74-0 1g $170 2026-06-03 Buy
Product number Packaging Price Buy
M15451 1g $57.5 Buy
M15451 5g $191 Buy
M0730 1g $118 Buy
M0730 5g $467 Buy
234261 1g $170 Buy

5-METHOXY-2-METHYLINDOLE Chemical Properties,Uses,Production

Description

5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.

Chemical Properties

white to light beige crystalline powder or

Uses

An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.

Uses

reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5

Uses

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Definition

ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.

References

https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

104-94-9
116-09-6
1076-74-0
Synthesis of 5-METHOXY-2-METHYLINDOLE from p-Anisidine and Hydroxyacetone
Global( 246)Suppliers
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Capot Chemical Co.,Ltd.
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View Lastest Price from 5-METHOXY-2-METHYLINDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-METHOXY-2-METHYLINDOLE pictures 2025-12-24 5-METHOXY-2-METHYLINDOLE
1076-74-0
1KG 98.0% 10 Shaanxi Dideu Medichem Co. Ltd
 5-Methoxy-2-methylindole pictures 2025-04-04 5-Methoxy-2-methylindole
1076-74-0
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-METHOXY-2-METHYLINDOLE pictures 2019-12-23 5-METHOXY-2-METHYLINDOLE
1076-74-0
1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.
5-Methoxy-2-methylindole, 99+% 5-METHOXY-2-METHYLINDOLE AKOS JY2082626 5-Methoxy-2-methyindole Indole, 5-methoxy-2-methyl- 5-Methoxy-2-Methylindole, 99+% 25GR 5-Methoxy-2-Methylindole, 99+% 5GR 2-Methyl-5-Methoxyindole NSC 63817 5-Methoxy-2-methylindole 99% 1H-Indole, 5-methoxy-2-methyl- 5-Methoxy-2-methylindole> 5-Methoxy-2-methylindole, 99%, for synthesis 1076-74-0 Heterocyclic Building Blocks Building Blocks Simple Indoles Indoles Building Blocks C10 Chemical Synthesis Heterocyclic Building Blocks Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Indoles Simple Indoles Building Blocks Heterocyclic Building Blocks Indole Indoles and derivatives