5-Methoxy-2-methylindole
- CAS No.
- 1076-74-0
- Chemical Name:
- 5-Methoxy-2-methylindole
- Synonyms
- NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-Methoxy-2-methylindole;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
- CBNumber:
- CB8174569
- Molecular Formula:
- C10H11NO
- Molecular Weight:
- 161.2
- MDL Number:
- MFCD00005620
- MOL File:
- 1076-74-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 86-88 °C (lit.) |
|---|---|
| Boiling point | 145 °C / 1.5mmHg |
| Density | 1.0840 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in methanol (very faint turbidity.) |
| form | Crystalline Powder or Crystals |
| pka | 17.28±0.30(Predicted) |
| color | White to light beige |
| InChI | InChI=1S/C10H11NO/c1-7-5-8-6-9(12-2)3-4-10(8)11-7/h3-6,11H,1-2H3 |
| InChIKey | VSWGLJOQFUMFOQ-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(OC)C=C2)C=C1C |
| CAS DataBase Reference | 1076-74-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
5-Methoxy-2-methylindole price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M15451 | 5-Methoxy-2-methylindole 99% | 1076-74-0 | 1g | $57.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | M15451 | 5-Methoxy-2-methylindole 99% | 1076-74-0 | 5g | $191 | 2026-04-30 | Buy |
| TCI Chemical | M0730 | 5-Methoxy-2-methylindole >99.0%(GC) | 1076-74-0 | 1g | $118 | 2026-04-30 | Buy |
| TCI Chemical | M0730 | 5-Methoxy-2-methylindole >99.0%(GC) | 1076-74-0 | 5g | $467 | 2026-04-30 | Buy |
| Usbiological | 234261 | 5-Methoxy-2-methylindole | 1076-74-0 | 1g | $170 | 2026-06-03 | Buy |
5-Methoxy-2-methylindole Chemical Properties, Uses, Production
Description
5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.
Chemical Properties
white to light beige crystalline powder or
Uses
An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.
Uses
reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5
Uses
It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.
Definition
ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.
References
https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451lang=en®ion=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure
5-Methoxy-2-methylindole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Guangchen Pharmaceutical Technology Co., Ltd | 18563726319 | 2845578351@qq.com | China | 7026 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
View Latest Price from 5-Methoxy-2-methylindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 5-METHOXY-2-METHYLINDOLE
1076-74-0
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-04-04 | 5-Methoxy-2-methylindole
1076-74-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-12-23 | 5-METHOXY-2-METHYLINDOLE
1076-74-0
|
1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 5-METHOXY-2-METHYLINDOLE
1076-74-0
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Methoxy-2-methylindole
1076-74-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-METHOXY-2-METHYLINDOLE
1076-74-0
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
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