BOC-LYS(TFA)-OH
- CAS No.
- 16965-06-3
- Chemical Name:
- BOC-LYS(TFA)-OH
- Synonyms
- NSC 164662;BOC-LYS(TFA)-OH;BOC-L-LYS(TFA)-OH;BOC-LYSINE(TFA)-OH;BOC-N-E-TFA-L-LYSINE;BOC-LYS(TFA)-OH USP/EP/BP;N-ALPHA-T-BOC-NE-TFA-L-LYS;BOC-N-EPSILON-TFA-L-LYSINE;Boc-(Trifluoroacetyl) Lysine;(Tert-Butoxy)Carbonyl Lys(Tfa)-OH
- CBNumber:
- CB8226628
- Molecular Formula:
- C13H21F3N2O5
- Molecular Weight:
- 342.31
- MDL Number:
- MFCD00037104
- MOL File:
- 16965-06-3.mol
- MSDS File:
- SDS
| Melting point | 102-105 °C |
|---|---|
| Boiling point | 485.6±45.0 °C(Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO. |
| form | Powder |
| pka | 3.97±0.21(Predicted) |
| color | White |
| optical activity | -12.72°(C=0.87g/100mI, DMF, 20°C, 589nm) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
BOC-LYS(TFA)-OH price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B657083 | Boc-Lys(Tfa)-OH | 16965-06-3 | 5g | $110 | 2021-12-16 | Buy |
| Usbiological | 264823 | N-alpha-Boc-Nε-trifluoroacetyl-L-lysine | 16965-06-3 | 5g | $395 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB47811 | N-alpha-Boc-Nepsilon-trifluoroacetyl-L-lysine | 16965-06-3 | 10g | $126.6 | 2021-12-16 | Buy |
| Iris Biotech GmbH | BAA5790 | Boc-L-Lys(TFA)-OH | 16965-06-3 | 25g | $303.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AAA0001597 | N-ALPHA-T-BOC-N-EPSILON-TRIFLUOROACETYL-L-LYSINE 95.00% | 16965-06-3 | 0.5G | $638 | 2021-12-16 | Buy |
BOC-LYS(TFA)-OH Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Boc-Lys(Tfa)-OH (cas# 16965-06-3) is a compound useful in organic synthesis.
Synthesis
24424-99-5
10009-20-8
96561-04-5
The general procedure for the synthesis of N2-(tert-butoxycarbonyl)-N6-(2,2,2-trifluoroacetyl)-D-lysine from di-tert-butyl dicarbonate and trifluoroacetyl-lysine was as follows: trifluoroacetyl-lysine (3.63 g, 0.015 mol) was suspended in 40 ml of N,N-dimethylformamide (DMF), to which was added triethylamine (TEA, 3.03 g , 0.03 mol) and di-tert-butyl dicarbonate (3.6 g, 0.0165 mol). The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the mixture was diluted with water to three times the original volume and acidified with hydrochloric acid to pH 2. The product was extracted with ethyl acetate (EtOAc, 100 ml), the organic phase was washed with water and saturated brine sequentially and dried with anhydrous magnesium sulfate (MgSO4). The solvent was removed by distillation under reduced pressure to afford (S)-2-((tert-butoxycarbonyl)amino)-6-(2,2,2-trifluoroacetamido)hexanoic acid (4.7 g, 92% yield). The analytical data of the product (3) were in agreement with literature reports.
References
[1] Patent: WO2009/114809, 2009, A1. Location in patent: Page/Page column 7-8
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 1, p. 255 - 258
BOC-LYS(TFA)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from BOC-LYS(TFA)-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | BOC-LYS(TFA)-OH
16965-06-3
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- BOC-LYS(TFA)-OH
16965-06-3
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
