3-FLUORO-O-XYLENE
- CAS No.
- 443-82-3
- Chemical Name:
- 3-FLUORO-O-XYLENE
- Synonyms
- 3-fluoro-o-xylen;3-FLUORO-O-XYLENE;3-Fluoroxylene,99%;3-FLUORO-1,2-XYLENE;o-Xylene, 3-fluoro-;3-Fluoroxylene, 99%;3-Fluoro-o-xylene>3-Fluoro-o-xylene,99%;2,3-DIMETHYLFLUOROBENZENE;1-FLUORO-2,3-DIMETHYLBENZENE
- CBNumber:
- CB8236449
- Molecular Formula:
- C8H9F
- Molecular Weight:
- 124.16
- MDL Number:
- MFCD00000323
- MOL File:
- 443-82-3.mol
- MSDS File:
- SDS
| Boiling point | 148-152 °C(lit.) |
|---|---|
| Density | 0.99 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 97 °F |
| storage temp. | Sealed in dry,2-8°C |
| form | clear liquid |
| Specific Gravity | 0.992 |
| color | Colorless to Almost colorless |
| Water Solubility | Insoluble in water. |
| BRN | 2040955 |
| CAS DataBase Reference | 443-82-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | 3-Fluoro-o-xylene(443-82-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P261-P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P370+P378-P403+P235-P501 | |||||||||
| Hazard Codes | F,Xi | |||||||||
| Risk Statements | 10-37 | |||||||||
| Safety Statements | 16-24/25 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ZE4560000 | |||||||||
| Hazard Note | Flammable | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29039990 | |||||||||
| NFPA 704 |
|
3-FLUORO-O-XYLENE price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0332 | 3-Fluoro-o-xylene >98.0%(GC) | 443-82-3 | 5mL | $42 | 2025-07-31 | Buy |
| TRC | F402320 | 3-Fluoro-O-xylene | 443-82-3 | 5g | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 004814 | 3-Fluoro-o-xylene 98% | 443-82-3 | 25g | $68 | 2021-12-16 | Buy |
| SynQuest Laboratories | 1700-3-23 | 2,3-Dimethylfluorobenzene 98% | 443-82-3 | 100g | $75 | 2021-12-16 | Buy |
| AK Scientific | X8294 | 3-Fluoro-o-xylene | 443-82-3 | 25g | $143 | 2021-12-16 | Buy |
3-FLUORO-O-XYLENE Chemical Properties,Uses,Production
Chemical Properties
clear colorless liquid
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Synthesis
87-59-2
443-82-3
Example 5: Synthesis of 2,3-dimethylfluorobenzene 1. Diazotization reaction: 2,3-dimethylaniline (2.3 g, 0.02 mol) was slowly added to Et3N-3HF (30 cm3) at 0 °C. Subsequently, sodium nitrite (2.0 g, 0.03 mol) was added in batches with the aid of ultrasound and significant gas release was observed for about 25 min. The reaction mixture gradually changed from clear to yellow and finally to dark color due to tar generation. 2. Post-treatment: the brown reaction mixture was poured into water (150 cm3) and extracted with ether (180 cm3 x 2). The remaining tar-like substance was transferred to Soxhlet extractor and extracted continuously with ether (30cm3) for 24 hours. All the ether extracts were combined and dried with magnesium sulphate and subsequently the ether was removed by fractional distillation to give a brown oily substance. 3. purification: the above oily substance was distilled at 142-143°C (atmospheric pressure) to give 1-fluoro-2,3-dimethylbenzene (1.47 g, 63.4% yield) as a clear liquid. 4. Characterization: - 1H NMR (CDCl3) δ: 2.18 (d, J = 2.0 Hz, 3H, 2-CH3), 2.28 (s, 3H, 3-CH3), 6.88 (t, J = 7.6 Hz, 1H, 6-H), 6.91 (d, J = 7.6 Hz, 1H, 4-H), 7.03 (q, J = 8.0 Hz and J = 6.0 Hz, 1H, 5 -H). - 19F NMR (CDCl3) δ: 118.3 (tq, J = 7.6Hz and J = 2.0Hz, 1-F). - Mass spectrum: molecular ion peak at m/z 124, and fragmentation peaks at m/z 109, 101, 96, 86, 83 and 77, consistent with the expected fragmentation pattern of 1-fluoro-2,3-dimethylbenzene.
References
[1] Patent: US6179970, 2001, B2
[2] Journal of the Chemical Society. Perkin Transactions 1, 2002, # 3, p. 402 - 415
[3] Proceedings - Indian Academy of Sciences, Section A, 1959, vol. 50, p. 51,56, 58, 59
[4] Journal of Organic Chemistry, 1961, vol. 26, p. 3208 - 3211
3-FLUORO-O-XYLENE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20195 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
View Lastest Price from 3-FLUORO-O-XYLENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-22 | 3-fluoro-o-xylene
443-82-3
|
US $0.00-0.00 / kg | 1kg | 99% | 1 | Jinan Ruitong Biotech Co., Ltd. | |
 |
2023-12-26 | 3-FLUORO-O-XYLENE
443-82-3
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-07-14 | 3-FLUORO-O-XYLENE
443-82-3
|
US $1.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 3-fluoro-o-xylene
443-82-3
- US $0.00-0.00 / kg
- 99%
- Jinan Ruitong Biotech Co., Ltd.
-
- 3-FLUORO-O-XYLENE
443-82-3
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-FLUORO-O-XYLENE
443-82-3
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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