Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>ON 146040

ON 146040

ON 146040 Structure
ON 146040 structure
CAS No.
1404231-34-0
Chemical Name:
ON 146040
Synonyms
ON 146040;ON 146040, 10 mM in DMSO;2-((4-(4-Methylpiperazin-1-yl)phenyl)amino)-7-(4-nitrobenzylidene)-5H-pyrimido[4,5-b][1,4]thiazin-6(7H)-one;(7Z)-2-[4-(4-methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one;5H-Pyrimido[4,5-b][1,4]thiazin-6(7H)-one, 2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-7-[(4-nitrophenyl)methylene]-
CBNumber:
CB82715663
Molecular Formula:
C24H23N7O3S
Molecular Weight:
489.55
MDL Number:
MFCD28167819
MOL File:
1404231-34-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-28 08:09:04
Product description Number Pack Size Price
(7Z)-2-[4-(4-Methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one EGC23134 25mg $1201
(7Z)-2-[4-(4-Methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one EGC23134 50mg $1670.5
ON 146040 95.05% CS-3348 5mg $325
ON 146040 95.05% CS-3348 10mg $520
ON 146040 AA009CB7 1mg $53
Request For Quotation

ON 146040 Properties

Density 1.424±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
pka 8.831±0.20(predicted)
color Brown to reddish brown

ON 146040 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth EGC23134 (7Z)-2-[4-(4-Methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one 1404231-34-0 25mg $1201 2026-06-04 Buy
Biosynth EGC23134 (7Z)-2-[4-(4-Methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one 1404231-34-0 50mg $1670.5 2026-06-04 Buy
ChemScene CS-3348 ON 146040 95.05% 1404231-34-0 5mg $325 2026-06-04 Buy
ChemScene CS-3348 ON 146040 95.05% 1404231-34-0 10mg $520 2026-06-04 Buy
aablocks AA009CB7 ON 146040 1404231-34-0 1mg $53 2026-05-28 Buy
Product number Packaging Price Buy
EGC23134 25mg $1201 Buy
EGC23134 50mg $1670.5 Buy
CS-3348 5mg $325 Buy
CS-3348 10mg $520 Buy
AA009CB7 1mg $53 Buy

ON 146040 Chemical Properties,Uses,Production

Uses

ON 146040 is a potent PI3Kα and PI3Kδ (IC50≈14 and 20 nM, respectively) inhibitor. ON 146040 also inhibits Abl1 (IC50<150 nM).

IC 50

PI3Kα: 14 nM (IC50); PI3Kδ: 20 nM (IC50); PI3Kγ: 1 μM (IC50); PI3Kβ: 3 μM (IC50)

References

[1] Targeting oncogenic STAT3 and STAT5 signaling with on 146040, a small molecule inhibitor of PI3K α/δ and BCR-ABL.

ON 146040 Preparation Products And Raw materials

Raw materials

Preparation Products

ON 146040 Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Aladdin Scientific 		tp@aladdinsci.com United States 50108 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9801 55
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27602 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
BOC Sciences 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai EFE Biological Technology Co., Ltd. 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Lastest Price from ON 146040 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ON 146040 pictures 2026-07-27 ON 146040
1404231-34-0
 $41.00-167.00 99.89% 10g TargetMol Chemicals Inc.
ON 146040 pictures 2026-07-27 ON 146040
1404231-34-0
 $41.00-167.00 99.89% 10g TargetMol Chemicals Inc.
  • ON 146040 pictures
  • ON 146040
    1404231-34-0
  • $41.00-167.00
  • 99.89%
  • TargetMol Chemicals Inc.
  • ON 146040 pictures
  • ON 146040
    1404231-34-0
  • $41.00-167.00
  • 99.89%
  • TargetMol Chemicals Inc.

ON 146040 Spectrum

ON 146040(1404231-34-0)1HNMR

1404231-34-0(ON 146040)Related Search:

NVP-BEZ 235 Isorhamnetin Anti-Aging Compound Library Protein Tyrosine Kinase Compound Library Anti-cancer compound library
Ponatinib

1of2

ON 146040 (7Z)-2-[4-(4-methylpiperazin-1-yl)anilino]-7-[(4-nitrophenyl)methylidene]-5H-pyrimido[4,5-b][1,4]thiazin-6-one 5H-Pyrimido[4,5-b][1,4]thiazin-6(7H)-one, 2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-7-[(4-nitrophenyl)methylene]- 2-((4-(4-Methylpiperazin-1-yl)phenyl)amino)-7-(4-nitrobenzylidene)-5H-pyrimido[4,5-b][1,4]thiazin-6(7H)-one ON 146040, 10 mM in DMSO 1404231-34-0 C24H23N7O3S