2-Bromo-4-chlorobenzoic acid
- CAS No.
- 936-08-3
- Chemical Name:
- 2-Bromo-4-chlorobenzoic acid
- Synonyms
- 2-BroMo-4-chlorobenz;Dapagliflozin Impurity 51;2-Bromo-4-chlorobenzoicaci;Dapagliflozin Impurity 159;2-BroM-4-chlorobenzoic acid;2-BROMO-4-CHLOROBENZOIC ACID;Benzoic acid, 2-bromo-4-chloro-;2-Bromo-4-chlorobenzoic Acid >2-Bromo-4-chlorobenzoic acid (ACI)
- CBNumber:
- CB8302052
- Molecular Formula:
- C7H4BrClO2
- Molecular Weight:
- 235.46
- MDL Number:
- MFCD00672930
- MOL File:
- 936-08-3.mol
- MSDS File:
- SDS
| Melting point | 157-161 °C |
|---|---|
| Boiling point | 326.5±27.0 °C(Predicted) |
| Density | 1.809±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 2.62±0.10(Predicted) |
| form | Solid |
| color | White to Light yellow |
| InChI | InChI=1S/C7H4BrClO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11) |
| InChIKey | USMQLFCVCDEXAK-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(Cl)C=C1Br |
| CAS DataBase Reference | 936-08-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335-H400 | |||||||||
| Precautionary statements | P273-P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | Xi,N,C,Xn | |||||||||
| Risk Statements | 36/37/38-50-34-22 | |||||||||
| Safety Statements | 26-36/37/39-61-45 | |||||||||
| RIDADR | UN 2928 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 2916399090 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Acute 1 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
2-Bromo-4-chlorobenzoic acid price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 681113 | 2-Bromo-4-chlorobenzoic acid 97% | 936-08-3 | 5g | $24.6 | 2023-06-20 | Buy |
| TCI Chemical | B4592 | 2-Bromo-4-chlorobenzoic Acid >96.0%(GC)(T) | 936-08-3 | 5g | $83 | 2026-04-30 | Buy |
| Usbiological | 264237 | 2-Bromo-4-chlorobenzoic acid Asreported | 936-08-3 | 5g | $290 | 2026-06-03 | Buy |
| Usbiological | 264237 | 2-Bromo-4-chlorobenzoic acid Asreported | 936-08-3 | 10g | $396 | 2026-06-03 | Buy |
| Usbiological | 264237 | 2-Bromo-4-chlorobenzoic acid Asreported | 936-08-3 | 25g | $499 | 2026-06-03 | Buy |
2-Bromo-4-chlorobenzoic acid Chemical Properties,Uses,Production
Synthesis
The crude acid (11a or 12a; 1.0 g) was dissolved in concentrated H2SO4 (10 cm3) and stirred for 5 h, then poured into 50 cm3 of ice water. The product was separated and washed with 5% Na2CO3 solution. The crude anthrone was dissolved in 30 cm3 of acetic acid. 2.00 g of saturated aqueous K2Cr2O7 solution was added, and the mixture was heated to 90°C for 1 hour. After cooling, the mixture was poured into 200 cm3 of water. The separated solid was filtered, chromatographically analyzed on a silica gel column (benzene, then chloroform), and purified by crystallization to give 2-bromo-4-chlorobenzoic acid. 13, yield (85.2%). M, p. 156-158°C, formula: (C7H4BrClO2), analytical results (%): C 35.51, H 1.80, NMR data: C (35.71), H (1.71). Infrared data: IR (cm⁻¹): 3100 (OH) 1705 (C=0); ¹H NMR δH (200 MHz, dimethyl sulfoxide-d⁶) = 13.5 (br s, ¹H, COOH), 7.88 (d, ¹H, J = 2.1 Hz, 3-Ar-H), 7.78 (d, ¹H, J = 8.4 Hz, 5-Ar-H), 7.57 (dd, ¹H, J1 = 2.1 Hz, J2 = 8.3 Hz, 6-Ar-H) ppm. alt="Synthetic route of 2-bromo-4-chlorobenzoic acid">
Figure 2-bromo-4-chlorobenzoic acid synthetic route
Uses
2-Bromo-4-chlorobenzoic acid is used in the production of pharmaceuticals, dye carriers, plasticizers, fragrances, and food preservatives. It is also used to improve the performance of alkyd resin coatings. Furthermore, it is used as an antifungal and disinfectant, serving as a chemical reagent and preservative. 2-Bromo-4-chlorobenzoic acid is commonly used as a fixative or preservative. It is also used as a flavoring agent in fruit juice beverages. Additionally, it can be used in flavorings for chocolate, lemon, orange, berry, nut, and candied fruit.
Chemical Properties
off-white powder
2-Bromo-4-chlorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Ruiyuanda New Materials Co., Ltd | 0510-15312278075 15312278075 | xxl_hotmail@163.com | China | 228 | 58 |
| Changzhou Run-chem Biotech Co., ltd | 15061933924 | 3301839366@qq.com | China | 932 | 58 |
| Weifang QianJin Fine Chemical Co., Ltd. | 18753684562 | 1577399715@qq.COM | China | 1772 | 55 |
| Changzhou Aifa Technology Co., Ltd | 0519-89892883 | jsafkj@126.com | China | 15 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
View Lastest Price from 2-Bromo-4-chlorobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Bromo-4-chlorobenzoic acid
936-08-3
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2026-02-02 | 2-Bromo-4-chlorobenzoic acid
936-08-3
|
10mg | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-06-27 | 2-Bromo-4-chlorobenzoic acid
936-08-3
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 2-Bromo-4-chlorobenzoic acid
936-08-3
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 2-Bromo-4-chlorobenzoic acid
936-08-3
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Bromo-4-chlorobenzoic acid
936-08-3
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
