13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester
- CAS No.
- 1172605-58-1
- Chemical Name:
- 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester
- Synonyms
- (9H-Fluoren-9-yl)methyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate;FmocNH-PEG3-CH2CH2N3;13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester;13-Azido-5,8,11-trioxa-2-azatridecanoic acid 9H-fluoro-9-yl methyl ester;FmocNH-PEG3-CH2CH2N3/5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-, 9H-fluoren-9-ylmethyl ester
- CBNumber:
- CB83101577
- Molecular Formula:
- C23H28N4O5
- Molecular Weight:
- 440.5
- MDL Number:
- MFCD28964125
- MOL File:
- 1172605-58-1.mol
- MSDS File:
- SDS
13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | AMTGC114 | 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-. 9H-fluoren-9-ylmethyl ester 97% | 1172605-58-1 | 1g | $138 | 2026-06-04 | Buy |
| AK Scientific | AMTGC114 | 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-. 9H-fluoren-9-ylmethyl ester 97% | 1172605-58-1 | 5g | $414 | 2026-06-04 | Buy |
| Iris Biotech GmbH | RL-4380 | (9H-fluoren-9-yl)methyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate | 1172605-58-1 | 500mg | $86.4 | 2026-05-19 | Buy |
| Iris Biotech GmbH | RL-4380 | (9H-fluoren-9-yl)methyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate | 1172605-58-1 | 1g | $134.4 | 2026-05-19 | Buy |
| Iris Biotech GmbH | RL-4380 | (9H-fluoren-9-yl)methyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate | 1172605-58-1 | 5g | $480 | 2026-05-19 | Buy |
13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Chemical Properties,Uses,Production
Uses
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fmoc-N-amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological Activity
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9965 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| shanghai Yanfeng biochemical technology Co.,LTD | 17721070236 13611955358 | yanfen2023@126.com | China | 2996 | 58 |
| Nanjing Bairuikang Biotechnology Co., Ltd. | 18168036974 | wangweicss@126.com | China | 1379 | 58 |
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3948 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38862 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
