FMOC-L-LEUCINOL
- CAS No.
- 139551-83-0
- Chemical Name:
- FMOC-L-LEUCINOL
- Synonyms
- FMOC-LEU-OL;Fmoc-L-Leu-OL;FMOC-LEUCINOL;FMOC-L-LEUCINOL;FMOC-LEU-OL 98+%;N-FMOC-L-LEUCINOL;Fmoc-Leucinol,97%;N-ALPHA-FMOC-L-LEUCINOL;REF DUPL: Fmoc-L-leucinol;Fmoc-L-leucinol≥ 98% (HPLC)
- CBNumber:
- CB8342948
- Molecular Formula:
- C21H25NO3
- Molecular Weight:
- 339.43
- MDL Number:
- MFCD00235932
- MOL File:
- 139551-83-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Fmoc-L-leucinol Asreported | 276992 | 2g | $353 |
| Fmoc-L-leucinol Asreported | 276992 | 5g | $575 |
| Fmoc-L-leucinol Asreported | 276992 | 10g | $801 |
| Fmoc-L-leucinol Asreported | 276992 | 25g | $1118 |
| Fmoc-L-leucinol (Fmoc-Leu-ol) ≥98%(HPLC) | 238461 | 1g | $312 |
| More product size | |||
| Melting point | 112-113 °C |
|---|---|
| Boiling point | 525.2±33.0 °C(Predicted) |
| Density | 1.148±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| pka | 11.48±0.46(Predicted) |
| Appearance | White to off-white Solid |
| optical activity | -18.3°(C=0.01g/ml MEOH) |
| CAS DataBase Reference | 139551-83-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
FMOC-L-LEUCINOL price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 276992 | Fmoc-L-leucinol Asreported | 139551-83-0 | 2g | $353 | 2026-06-03 | Buy |
| Usbiological | 276992 | Fmoc-L-leucinol Asreported | 139551-83-0 | 5g | $575 | 2026-06-03 | Buy |
| Usbiological | 276992 | Fmoc-L-leucinol Asreported | 139551-83-0 | 10g | $801 | 2026-06-03 | Buy |
| Usbiological | 276992 | Fmoc-L-leucinol Asreported | 139551-83-0 | 25g | $1118 | 2026-06-03 | Buy |
| Usbiological | 238461 | Fmoc-L-leucinol (Fmoc-Leu-ol) ≥98%(HPLC) | 139551-83-0 | 1g | $312 | 2026-06-03 | Buy |
FMOC-L-LEUCINOL Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Fmoc-L-leucinol is an intermediate used in the preparation of Fmoc-protected amino azides from Fmoc-protected amino alcohols.
Synthesis
35661-60-0
139551-83-0
GENERAL METHOD: To a tetrahydrofuran (THF, 10 mL) solution of Fmoc-L-leucine (10 mmol) was sequentially added N,N-diisopropylethylamine (DIPEA, 11 mmol, 1.42 mL) and 50% propylphosphonic anhydride (T3P) in ethyl acetate (EtOAc) solution (20 mmol, 6.36 mL) at 0 °C and the reaction mixture was stirred for about 10 min at this temperature. The reaction mixture was stirred for about 10 minutes. Subsequently, an aqueous solution of sodium borohydride (NaBH4, 10 mmol, 388 mg) (0.3 mL) was slowly added to the reaction system at the same temperature and the reaction was continuously stirred until the reaction was completed by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by rotary evaporator and the crude product was extracted with ethyl acetate (EtOAc). The organic phase was washed sequentially with 5% aqueous citric acid (10 mL × 2), 5% aqueous sodium carbonate (Na2CO3) (10 mL × 2), water and saturated saline. The organic layer was dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to obtain Fmoc-L-leucinol.
References
[1] Journal of Organic Chemistry, 2001, vol. 66, # 25, p. 8454 - 8462
[2] Angewandte Chemie - International Edition, 2010, vol. 49, # 1, p. 117 - 120
[3] Organic and Biomolecular Chemistry, 2010, vol. 8, # 21, p. 4855 - 4860
[4] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[5] Organic Letters, 2008, vol. 10, # 10, p. 1881 - 1884
FMOC-L-LEUCINOL Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-15680023009 | ni@enlaibio.com | China | 1103 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 15301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
View Lastest Price from FMOC-L-LEUCINOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-29 | Fmoc-Leu-OL
139551-83-0
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd |
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- Fmoc-Leu-OL
139551-83-0
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
