Phenmedipham
- CAS No.
- 13684-63-4
- Chemical Name:
- Phenmedipham
- Synonyms
- FENDER;M75;Gusto;EP-452;Pistol;sn4075;Suplex;BEETUP;ALEGRO;EP-462
- CBNumber:
- CB8404828
- Molecular Formula:
- C16H16N2O4
- Molecular Weight:
- 300.31
- MDL Number:
- MFCD00055419
- MOL File:
- 13684-63-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 140-144°C |
|---|---|
| Boiling point | 441.54°C (rough estimate) |
| Density | 1.1782 (rough estimate) |
| refractive index | 1.6240 (estimate) |
| Flash point | 100 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 13.03±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| Water Solubility | <0.1 g/100 mL at 21 ºC |
| BRN | 2395027 |
| Henry's Law Constant | 1.2×107 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Major Application |
agriculture environmental |
| InChI | 1S/C16H16N2O4/c1-11-5-3-6-12(9-11)18-16(20)22-14-8-4-7-13(10-14)17-15(19)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20) |
| InChIKey | IDOWTHOLJBTAFI-UHFFFAOYSA-N |
| SMILES | COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 |
| LogP | 3.590 |
| CAS DataBase Reference | 13684-63-4(CAS DataBase Reference) |
| EWG's Food Scores | 4 |
| FDA UNII | UJE31KXP78 |
| NIST Chemistry Reference | Methyl 3-m-tolylcarbamoyloxyphenylcarbamate(13684-63-4) |
| EPA Substance Registry System | Phenmedipham (13684-63-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H410 |
| Precautionary statements | P273-P391-P501 |
| PPE | Eyeshields, Faceshields, Gloves |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 |
| WGK Germany | 2 |
| RTECS | FD9050000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 |
| Hazardous Substances Data | 13684-63-4(Hazardous Substances Data) |
| Toxicity | (96-hour) for bluegill sunfish 3.98 mg/L, rainbow trout 1.4–3.0 mg/L, Daphnia magna 3.2 mg/L (Worthing and Hance, 1991), harlequin fish 16.5 mg/L (Hartley and Kidd, 1987); acute oral LD50 of pure phenmedipham and the formulated product for rats 3,700 and 10,300 mg/kg, respectively (Ashton and Monaco, 1991). |
Phenmedipham price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 36192 | Phenmedipham PESTANAL | 13684-63-4 | 100mg | $79 | 2026-04-30 | Buy |
| Usbiological | 165905 | Phenmedipham | 13684-63-4 | 500mg | $418 | 2026-06-03 | Buy |
| ChemScene | CS-0014127 | Phenmedipham 98.38% | 13684-63-4 | 5mg | $27 | 2026-06-04 | Buy |
| ChemScene | CS-0014127 | Phenmedipham 98.38% | 13684-63-4 | 10mg | $38 | 2026-06-04 | Buy |
| ChemScene | CS-0014127 | Phenmedipham 98.38% | 13684-63-4 | 25mg | $60 | 2026-06-04 | Buy |
Phenmedipham Chemical Properties, Uses, Production
Description
Phenmedipham is a carbamate herbicide used for the control of broadleaved weeds. It has a low aqueous solubility, a low volatility and is not generally expected to leach to groundwaters. It is not normally persistent in soil or water systems. It has a low mammalian toxicity but has been associated with the development of some cancers. Phenmedipham is moderately toxic to most aquatic and terrestrial fauna and flora.
Chemical Properties
Colorless crystalline solid, or needles; white powder. Odorless. Commercial product is available as an emulsifiable concentrate
Uses
Postemergence herbicide used to control weeds such as chickweed, dogfennel, foxtail, kochia, nightshade and yellow mustard, in strawberries, beet crops and spinach
Uses
Phenmedipham is an carbanilate selective herbicide used post-emergence in beet crops after the emergence of most broad-leaved weeds and before they develop.
Uses
Herbicide.
Definition
ChEBI: A carbamate ester that is (3-methylphenyl)carbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(methoxycarbonyl)amino]phenyl group.
General Description
Colorless crystals or white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. 3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate is incompatible with alkaline preparations.
Fire Hazard
Flash point data for 3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate are not available, however 3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate is probably combustible.
Agricultural Uses
Herbicide: A post-emergence herbicide for control of annual broadleaf weeds and grasses in sugar beets, spinach, strawberries, and sunflowers
Trade name
AIMSAN®; BETAMIX® (phenmedipham + desmedipham); BETANAL®; CQ 1451® (phenmedipham + desmedipham + ethofumesate); EC herbicide (phenmedipham + desmedipham + ethofumesate); EP 452®; KEEPER®; KEMIFAM®; MSS HERBASAN®; NA 305® (phenmedipham + desmedipham + ethofumesate); NA 308® (phenmedipham + desmedipham + ethofumesate); POWERTWIN® (phenmedipham + ethofumesate); PROGRESS® (phenmedipham + desmedipham + ethofumesate); S-4075®; SCHERING 4072®; SN 38584®; SPINAID ®; SYNBETAN-P®; TWIN®; VANGARD®
Mechanism of action
Inhibits photosynthesis (photosystem II) and acts by disrupting carbon dioxide. It is a contact herbicide which is absorbed through the leaves with translocation primarily in the apoplast.
Synthesis
13683-89-1
621-29-4
620-50-8
13684-63-4
Example 6: Preparation of methyl (3-(3-tolyl-carbamoyloxy)phenyl)carbamate Methyl N-(3-hydroxyphenyl)carbamate (8.35 g, 0.05 mol, prepared according to the method described in Example 1) was placed in a 150 mL beaker fitted with a stirrer, and water (75 mL) was added and stirred to mix. Borax (2.0 g) was added to the reaction system, followed by the slow dropwise addition of 3-tolyl isocyanate (5.3 g, 0.04 mol) through a dispensing funnel over a period of 45 minutes, with no need to adjust the temperature during the reaction. The pH was maintained at 9.2 during the reaction. after the dropwise addition, the reaction mixture was continued to be stirred for 1 hr. Upon completion of the reaction, the resulting finely suspended powdered product was filtered, washed with water and dried to afford the title compound (12.0 g, 100% yield, calculated on the basis of 3-tolyl isocyanate), melting point not determined.HPLC analysis showed the product to be 95.2% pure, with the remaining 4.8% consisting of unreacted N-(3-hydroxyphenyl)carbamic acid methyl ester and the by-products N,N'-di-3-tolylurea. -tolylurea.
Potential Exposure
A postemergence bis-carbamate/ carbamate ester herbicide used to control of annual broadleaf weeds and grasses in sugar beets, spinach, strawberries, and sunflowers.
Environmental Fate
Soil. Phenmedipham degraded in soil forming methyl N-(3-hydroxyphenyl)-carbamate
and m-aminophenol (Hartley and Kidd, 1987). Hydrolysis yields m-aminophenol (Rajagopal et al., 1989). The reported half-life in soil is approximately 20 days (Rajagopal et
al., 1989) and 26 days (Worthing and Hance, 1991)
Plant. In plants, methyl N-(3-hydroxyphenyl)carbamate is the major metabolite (Hartley and Kidd, 1987)
Photolytic. Bussacchini et al. (1985) studied the photolysis (λ = 254 nm) of phenmedipham in ethanol, ethanol/water and hexane as solvents. In their proposed free radical
mechanism, homolysis of the carbon-oxygen bond of the carbamate linkage ga
Shipping
UN2757 Carbamate pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material,
Incompatibilities
Decomposes .145C. Esters ith acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Carbamates are incompatible with reducing agents, strong acids, oxidizing acids, peroxides, and bases. Contact with active metals or nitrides cause the release of flammable, and potentially explosive, hydrogen gas. Releases oxides of nitrogen and carbon when heated to decomposition.
Waste Disposal
Do not discharge into drains or sewers. Dispose of waste material as hazardous waste using a licensed disposal contractor to an approved landfill. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Incineration with effluent gas scrubbing is recommended. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
References
[1] Patent: US4748265, 1988, A
Pesticide Type
Herbicide
Phenmedipham Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
View Latest Price from Phenmedipham manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Phenmedipham
13684-63-4
|
$29.00-68.00 | 99.36% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-14 | phenmedipham
13684-63-4
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2025-07-29 | 3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate
13684-63-4
|
$6.00 | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd |
-
- Phenmedipham
13684-63-4
- $29.00-68.00
- 99.36%
- TargetMol Chemicals Inc.
-
- phenmedipham
13684-63-4
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-
- 3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate
13684-63-4
- $6.00
- 99%
- HebeiShuoshengImportandExportco.,Ltd
