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4-Chloro-4'-hydroxybenzophenone

CAS No.
42019-78-3
Chemical Name:
4-Chloro-4'-hydroxybenzophenone
Synonyms
4-CHLORO-4-HYDROXYBENZOPHENONE;NSC4056;4-(4-CHLOROBENZOYL)PHENOL;NSC 4056;NSC-4056;4-Chloro-4'-;4-Chloro-4'EP-A /USP RC A;4-Chloro-4'-hydroxyb;-hydroxybenzophenone
CBNumber:
CB8435031
Molecular Formula:
C13H9ClO2
Molecular Weight:
232.66
MDL Number:
MFCD00002357
MOL File:
42019-78-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:18:16
Product description Number Pack Size Price
Fenofibrate Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material PHR2864 50MG $797
Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard F0048005 15 mg $167
Fenofibrate Related Compound A United States Pharmacopeia (USP) Reference Standard 1269607 25mg $1390
Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard F0048005 f0048005 $153
4-Chloro-4'-hydroxybenzophenone >98.0%(GC) C1155 25g $54
More product size

4-Chloro-4'-hydroxybenzophenone Properties

Melting point 177-181 °C
Boiling point 257 °C (13 mmHg)
Density 1.2082 (rough estimate)
refractive index 1.5434 (estimate)
Flash point 100 °C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 7.68±0.15(Predicted)
form solid
color Pale Beige to Light Brown
BRN 2049956
Major Application pharmaceutical small molecule
InChI InChI=1S/C13H9ClO2/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,15H
InChIKey RUETVLNXAGWCDS-UHFFFAOYSA-N
SMILES C(C1=CC=C(Cl)C=C1)(C1=CC=C(O)C=C1)=O
CAS DataBase Reference 42019-78-3(CAS DataBase Reference)
FDA UNII FF9YB926A3
NIST Chemistry Reference Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-(42019-78-3)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261-P280a-P304+P340-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  24/25-37/39-26-36
WGK Germany  WGK 3
Hazard Note  Irritant
HS Code  29144000
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
0
0 0

4-Chloro-4'-hydroxybenzophenone price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2864 Fenofibrate Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 42019-78-3 50MG $797 2026-04-30 Buy
Sigma-Aldrich F0048005 Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard 42019-78-3 15 mg $167 2026-04-30 Buy
Sigma-Aldrich 1269607 Fenofibrate Related Compound A United States Pharmacopeia (USP) Reference Standard 42019-78-3 25mg $1390 2026-04-30 Buy
Sigma-Aldrich F0048005 Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard 42019-78-3 f0048005 $153 2024-03-01 Buy
TCI Chemical C1155 4-Chloro-4'-hydroxybenzophenone >98.0%(GC) 42019-78-3 25g $54 2026-04-30 Buy
Product number Packaging Price Buy
PHR2864 50MG $797 Buy
F0048005 15 mg $167 Buy
1269607 25mg $1390 Buy
F0048005 f0048005 $153 Buy
C1155 25g $54 Buy

4-Chloro-4'-hydroxybenzophenone Chemical Properties,Uses,Production

Chemical Properties

light grey to beige-brown powder

Uses

4-Chloro-4’-hydroxybenzophenone (Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A) the impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.

Preparation

Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
in the presence of trifluoromethanesulfonic acid at 45–55° (94%).

623-03-0
108-95-2
42019-78-3
Synthesis of 4-Chloro-4'-hydroxybenzophenone from 4-Chlorobenzonitrile and Phenol
Global( 600)Suppliers
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SINO HIGH(CHINA)CO.,LTD.
+86-2558392388 +86-13914336446 chang@sinohighchem.com China 34 58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
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Hebei Chuanghai Biotechnology Co., Ltd
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career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58

View Lastest Price from 4-Chloro-4'-hydroxybenzophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloro-4'-hydroxybenzophenone pictures 2026-06-05 4-Chloro-4'-hydroxybenzophenone
42019-78-3
1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Chloro-4'-hydroxybenzophenone pictures 2026-06-05 4-Chloro-4'-hydroxybenzophenone
42019-78-3
0.99 RongNa Biotechnology Co.,Ltd
4-Chloro-4'-hydroxybenzophenone pictures 2026-05-28 4-Chloro-4'-hydroxybenzophenone
42019-78-3
1KG 99% 100tons Hebei Chuanghai Biotechnology Co,.LTD
4-hydroxy-4’-chloro-benophenone Fenofibrate Impurity Ⅰ:4-Chloro-4'-hydroxybenzophenone 4-Chloro-4'-Hydroxybenzophenone 4-Hydroxy-4'-Chlorobenzophenone 4-p-Chlorobenzoylphenol 4-(4-Chlorobenzoyl)-4-Hydroxypiperidine 4-Chloro-4'-hydroxybenzophenon LABOTEST-BB LT00248477 METHANONE, (4-CHLOROPHENYL)(4-HYDROXYPHENYL)- 4-HYDROXY-4'-CHLOROBENZOPHENONE (4-CHLORO-PHENYL)-(4-HYDROXY-PHENYL)-METHANONE 4-CHLORO-4''-HYDROXYBENZOPHENONE=99.0% 8) 4-CHLORO 4-HYDROXY BENZOPHENONE 4-CHLORO-4''-HYDROXYBENZOPHENONEFENOFIBRATE 4,4'-Chlorohydroxybenzophenone 4-Chloro-4'-hydroxybenzophenone,98% 4-Chloro-4'-hydroxyb Fenofibrate Related Compound A (25 mg) ((4-chlorophenyl)(4-hydroxyphenyl)methanone) (4-chlorophenyl)(4-hydroxyphenyl)MethaNAne Fenofibrate EP IMpurity A Chloro-4'-hydroxybenzophe -4'-two4-chlorinehydroxylbenzophenone Fenofibrate Related Compound A (4-Chloro-4'-Hydroxybenzophenone) 4-Chloro-4'-hydroxybenzophenone≥ 99% (GC) 1-(4-Chlorophenyl)-1-(4-hydroxyphenyl)methanone Benzophenone,4-chloro-4'-hydroxy- (6CI) Choline Fenofibrate Impurity A Fenofibrate impurity A (EP) -G Fenofibrate impurity A (EP) 4-Chloro-4'-hydroxybenzoph Fenofibrate Impurity 1(Fenofibrate EP Impurity A) 4-Chloro-4'-hydroxybenzophenone benzophenone 4-Chloro-4'- 4-Chloro-4'-hydroxybenzophenone> Fenofibrate impurity A CRS Fenofibrate Related Impurity A Fenofibrate EP Impurity A/ Fenofibrate Related Compound A Fenofibrate EP Impurity AQ: What is Fenofibrate EP Impurity A Q: What is the CAS Number of Fenofibrate EP Impurity A Q: What is the storage condition of Fenofibrate EP Impurity A Q: What are the applications of Fenofibrate EP Impurity A Fenofibrate impurity A (F0048005) Fenofibrate Impurity 2 Fenofibrate Related Compound A ((4-chlorophenyl)(4-hydroxyphenyl)methanone) (1269607) NSC 4056 NSC-4056 Choline Fenofibrate EP Impurity A Fenofibrate USP Related Compound A 4-Chloro-4' -hydroxybenzophenone 5-Chloro-4’-hydroxybenzophenone EP-A /USP RC A 4-Chloro-4'-hydroxybenzophenone Fenofibrate Related Compound I [(4-chlorophenyl)(4-hydroxyphenyl)methanone] 4-Chloro-4''-hydroxybenzophenone, 10 mM in DMSO 4-Chloro-4'-hydroxydibenzoyl Fenofibrate Impurity 24 (INT2) Procetofene impurity A (4-Chlorophenyl)(4-hydroxyphenyl)methanone (Fenofibrate Impurity) Fenofibrate EP Impurity A (Fenofibrate USP Related Compound A) 4-(4-CHLOROBENZOYL)PHENOL 4-CHLORO-4-HYDROXYBENZOPHENONE