4-Chloro-4'-hydroxybenzophenone
- CAS No.
- 42019-78-3
- Chemical Name:
- 4-Chloro-4'-hydroxybenzophenone
- Synonyms
- 4-CHLORO-4-HYDROXYBENZOPHENONE;NSC4056;4-(4-CHLOROBENZOYL)PHENOL;NSC 4056;NSC-4056;4-Chloro-4'-;4-Chloro-4'EP-A /USP RC A;4-Chloro-4'-hydroxyb;-hydroxybenzophenone
- CBNumber:
- CB8435031
- Molecular Formula:
- C13H9ClO2
- Molecular Weight:
- 232.66
- MDL Number:
- MFCD00002357
- MOL File:
- 42019-78-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Fenofibrate Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | PHR2864 | 50MG | $797 |
| Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard | F0048005 | 15 mg | $167 |
| Fenofibrate Related Compound A United States Pharmacopeia (USP) Reference Standard | 1269607 | 25mg | $1390 |
| Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard | F0048005 | f0048005 | $153 |
| 4-Chloro-4'-hydroxybenzophenone >98.0%(GC) | C1155 | 25g | $54 |
| More product size | |||
| Melting point | 177-181 °C |
|---|---|
| Boiling point | 257 °C (13 mmHg) |
| Density | 1.2082 (rough estimate) |
| refractive index | 1.5434 (estimate) |
| Flash point | 100 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| pka | 7.68±0.15(Predicted) |
| form | solid |
| color | Pale Beige to Light Brown |
| BRN | 2049956 |
| Major Application | pharmaceutical small molecule |
| InChI | InChI=1S/C13H9ClO2/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,15H |
| InChIKey | RUETVLNXAGWCDS-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(Cl)C=C1)(C1=CC=C(O)C=C1)=O |
| CAS DataBase Reference | 42019-78-3(CAS DataBase Reference) |
| FDA UNII | FF9YB926A3 |
| NIST Chemistry Reference | Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-(42019-78-3) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 24/25-37/39-26-36 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29144000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Chloro-4'-hydroxybenzophenone price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2864 | Fenofibrate Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 42019-78-3 | 50MG | $797 | 2026-04-30 | Buy |
| Sigma-Aldrich | F0048005 | Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard | 42019-78-3 | 15 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1269607 | Fenofibrate Related Compound A United States Pharmacopeia (USP) Reference Standard | 42019-78-3 | 25mg | $1390 | 2026-04-30 | Buy |
| Sigma-Aldrich | F0048005 | Fenofibrate impurity A European Pharmacopoeia (EP) Reference Standard | 42019-78-3 | f0048005 | $153 | 2024-03-01 | Buy |
| TCI Chemical | C1155 | 4-Chloro-4'-hydroxybenzophenone >98.0%(GC) | 42019-78-3 | 25g | $54 | 2026-04-30 | Buy |
4-Chloro-4'-hydroxybenzophenone Chemical Properties,Uses,Production
Chemical Properties
light grey to beige-brown powder
Uses
4-Chloro-4’-hydroxybenzophenone (Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A) the impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.
Preparation
Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
in the presence of trifluoromethanesulfonic acid at 45–55° (94%).
4-Chloro-4'-hydroxybenzophenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SINO HIGH(CHINA)CO.,LTD. | +86-2558392388 +86-13914336446 | chang@sinohighchem.com | China | 34 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +86-519-85525359 +86-15995072465 | sales@xuanmingchem.com | China | 912 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 427 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
View Lastest Price from 4-Chloro-4'-hydroxybenzophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-06-05 | 4-Chloro-4'-hydroxybenzophenone
42019-78-3
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-06-05 | 4-Chloro-4'-hydroxybenzophenone
42019-78-3
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
![]() |
2026-05-28 | 4-Chloro-4'-hydroxybenzophenone
42019-78-3
|
1KG | 99% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD |
-

- 4-Chloro-4'-hydroxybenzophenone
42019-78-3
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 4-Chloro-4'-hydroxybenzophenone
42019-78-3
- 0.99
- RongNa Biotechnology Co.,Ltd
-

- 4-Chloro-4'-hydroxybenzophenone
42019-78-3
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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