ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- CAS No.
- 53090-46-3
- Chemical Name:
- ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- Synonyms
- ETHYL-3-THIOPHENOYL-ACETATE;Ethyl 3-oxo-3-(3-thienyl)propionate;2-[oxo(3-thiophenyl)methyl]butanoate;Ethyl 3-oxo-3-(thien-3-yl)propanoate;ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE;3-Thiophenepropanoic acid, β-oxo-, ethyl ester
- CBNumber:
- CB8707679
- Molecular Formula:
- C9H10O3S
- Molecular Weight:
- 198.24
- MDL Number:
- MFCD07779220
- MOL File:
- 53090-46-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 3-oxo-3-(thiophen-3-yl)propanoate 97% | P000269464 | 1g | $101 |
| Ethyl 3-oxo-3-(thiophen-3-yl)propanoate 97% | P000269464 | 5g | $327 |
| Ethyl3-oxo-3-(thiophen-3-yl)propanoate | 7525AB | 250mg | $119 |
| Ethyl3-oxo-3-(thiophen-3-yl)propanoate | 7525AB | 1g | $200 |
| ETHYL-3-OXO-3-(THIOPHEN-3-YL)PROPANOATE 95.00% | CHM0151880 | 5MG | $500.79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| HS Code | 2934999090 |
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Ark Pharm | P000269464 | Ethyl 3-oxo-3-(thiophen-3-yl)propanoate 97% | 53090-46-3 | 1g | $101 | 2021-12-16 | Buy |
| Ark Pharm | P000269464 | Ethyl 3-oxo-3-(thiophen-3-yl)propanoate 97% | 53090-46-3 | 5g | $327 | 2021-12-16 | Buy |
| AK Scientific | 7525AB | Ethyl3-oxo-3-(thiophen-3-yl)propanoate | 53090-46-3 | 250mg | $119 | 2021-12-16 | Buy |
| AK Scientific | 7525AB | Ethyl3-oxo-3-(thiophen-3-yl)propanoate | 53090-46-3 | 1g | $200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0151880 | ETHYL-3-OXO-3-(THIOPHEN-3-YL)PROPANOATE 95.00% | 53090-46-3 | 5MG | $500.79 | 2021-12-16 | Buy |
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Chemical Properties,Uses,Production
Synthesis
1468-83-3
53090-46-3
General procedure for the synthesis of ethyl 3-oxo-3-(3-thienyl)propionate from 3-acetylthiophene: First, diethyl carbonate (36.3 mL, 300 mmol) was dissolved in toluene (18 mL) and the solution was heated to 60 °C. At this temperature, potassium tert-butoxide (13.0 g, 120 mmol) was added in batches, and after the addition, the reaction mixture was continued to be heated at 65°C for half an hour. Subsequently, the temperature was raised to 75 °C and a solution of 3-methylthiophene (9.2 g, 73 mmol) in toluene (18 mL) was slowly added dropwise. After the dropwise addition, the reaction mixture was heated at 80 °C for 90 min. After completion of the reaction, it was cooled to room temperature, the precipitated solid was collected by filtration and washed thoroughly with ether. The resulting solid was dissolved in water and extracted successively with ethyl acetate. The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate, filtered and the solvent was evaporated to give the dark oily product ethyl 3-oxo-3-(3-thienyl)propionate (12.0 g, 83% yield). The NMR hydrogen spectrum (CDCl3) data of the product were as follows: δ 1.25 (t, 3H), 3.90 (s, 2H), 4.20 (q, 2H), 7.35 (m, 1H), 7.55 (m, 1H), 8.10 (m, 1H).
References
[1] Patent: WO2005/123693, 2005, A1. Location in patent: Page/Page column 57-58
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49968 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| China Langchem Inc. | 0086-21-58956006 | China | 7811 | 57 | |
| Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 6387 | 52 |
| Sci General Material & Chemical Ltd | 021-58388037;21-58388037 13472507714 | 35177634@qq.com;1589045147@qq.com | China | 781 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9858 | 55 |
