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Indole-7-carboxaldehyde

Indole-7-carboxaldehyde Structure
Indole-7-carboxaldehyde structure
CAS No.
1074-88-0
Chemical Name:
Indole-7-carboxaldehyde
Synonyms
1H-INDOLE-7-CARBALDEHYDE;1H-INDOLE-5-CARBALDEHYDE;e-7-carboxaL;7-FORMYLINDOLE;7-Indolealdehyde;INDOLE-7-ALDEHYDE;7-Formyl-1H-indole;RARECHEM AH BS 0111;INDOLE-7-CARBALDEHYDE;7-Indolecarboxaldehyde
CBNumber:
CB8731641
Molecular Formula:
C9H7NO
Molecular Weight:
145.16
MDL Number:
MFCD01318152
MOL File:
1074-88-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:22:17
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Indole-7-carboxaldehyde Properties

Melting point 87-91 °C (lit.)
Boiling point 339.1±15.0 °C(Predicted)
Density 1.278±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane
form Solid
pka 15.50±0.30(Predicted)
color Yellow Crystalline
Water Solubility insoluble
Sensitive Air Sensitive
BRN 1524960
InChI InChI=1S/C9H7NO/c11-6-8-3-1-2-7-4-5-10-9(7)8/h1-6,10H
InChIKey XQVZDADGTFJAFM-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2C=O)C=C1
CAS DataBase Reference 1074-88-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330-P302+P352
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-43
Safety Statements  36/37
WGK Germany  3
F  10
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Skin Sens. 1
NFPA 704
1
2 0

Indole-7-carboxaldehyde price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 632414 Indole-7-carboxaldehyde 97% 1074-88-0 1g $120 2026-04-30 Buy
Sigma-Aldrich 632414 Indole-7-carboxaldehyde 97% 1074-88-0 5g $303 2023-06-20 Buy
TCI Chemical I0701 1H-Indole-7-carbaldehyde min. 98.0 % 1074-88-0 1G $46 2026-04-30 Buy
TCI Chemical I0701 1H-Indole-7-carbaldehyde min. 98.0 % 1074-88-0 5G $139 2026-04-30 Buy
Usbiological I0797-77E Indole-7-carboxaldehyde (7-Formylindole) 250mg $347 2026-06-03 Buy
Product number Packaging Price Buy
632414 1g $120 Buy
632414 5g $303 Buy
I0701 1G $46 Buy
I0701 5G $139 Buy
I0797-77E 250mg $347 Buy

Indole-7-carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Indole-7-carboxaldehyde is used in an efficient synthesis of fused pyrroloquinolinedicarboxylates from acetylenedicarboxylates and triphenylphosphine. 1.reactant for preparation of antiandrogens. 2.reactant for preparation of antiplatelet agent. 3.reactant for preparation of liver

Uses

Indole-7-carboxaldehyde (cas# 1074-88-0) is a compound useful in organic synthesis.

Definition

ChEBI: Indole-7-carboxaldehyde is a member of indoles.

Synthesis Reference(s)

Synthetic Communications, 36, p. 1051, 2006 DOI: 10.1080/00397910500503470

Synthesis

INDOLE-7-METHANOL

1074-87-9

Indole-7-carboxaldehyde

1074-88-0

General procedure for the synthesis of indole-7-carboxaldehyde from (1H-indol-7-yl)methanol: (1H-indol-7-yl)methanol (8.0 g, 54.3 mmol) was dissolved in 400 mL of dichloromethane, and activated manganese(IV) oxide (85%, 41.0 g, 0.40 mol) was added. The reaction mixture was stirred at room temperature for 72 hours. Upon completion of the reaction, 200 mL of dichloromethane and 400 mL of methanol were added to the mixture, followed by filtration through a silica gel pad to remove solid impurities. The filtrate was concentrated to give the crude product, which was further purified by silica gel column chromatography to afford the target product 1H-indole-7-carboxaldehyde (I-1) (6.55 g, 83% yield). The structure of the product was confirmed by 1H-NMR (CDCl3).

References

[1] Synthetic Communications, 2006, vol. 36, # 8, p. 1051 - 1056
[2] Patent: US2006/79520, 2006, A1. Location in patent: Page/Page column 43
[3] Patent: WO2006/44415, 2006, A2. Location in patent: Page/Page column 78; 106-107
[4] Journal of the American Chemical Society, 2006, vol. 128, # 12, p. 4023 - 4034
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 10, p. 4116 - 4125

Indole-7-carboxaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Manganese dioxide Titanous chloride Lithium Aluminum Hydride N,N-Dimethylformamide dimethyl acetal
3-Methyl-2-nitrobenzoic acid Indole-7-methanol Dichloromethane

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Preparation Products

ethyl 3-(1H-indol-7-yl)propanoate 7-ForMyl-1-Methyl-1H-indole-3-carbonitrile 7-ForMyl-1H-indole-3-carbonitrile 3-Iodo-1-methyl-1H-indole-7-carbaldehyde S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Indole-7-carboxaldehyde Suppliers

Global( 249)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Finechem Biotechnology Co., Ltd. 15821337685 hwh-chem@163.com China 94 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Yangzhou Siyu Chemical Co.,Ltd. 0514-87325867 sales@siyuchem.com China 370 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Shanghai Finechem Biotechnology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Yangzhou Siyu Chemical Co.,Ltd. 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

View Lastest Price from Indole-7-carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indole-7-carboxaldehyde pictures 2025-04-04 Indole-7-carboxaldehyde
1074-88-0
 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
7-Formylindole Indole-7-carboxaldehyde in stock Factory pictures 2020-06-02 7-Formylindole Indole-7-carboxaldehyde in stock Factory
1074-88-0
$1.00 1KG TOP 3 Factory in China Chemwill Asia Co.,Ltd.
Indole-7-carboxaldehyde pictures 2019-12-26 Indole-7-carboxaldehyde
1074-88-0
 $1.00 1KG 99% 200kg Career Henan Chemical Co

Indole-7-carboxaldehyde Spectrum

Indole-7-carboxaldehyde(1074-88-0)1HNMR

1074-88-0(Indole-7-carboxaldehyde)Related Search:

Indole Formaldehyde Indometacin Indole-3-butyric acid Indole-3-acetic acid
Indole-6-carboxaldehyde Ethyl indole-3-carboxylate Indole-7-boronic acid pinacol ester 3-Indoxyl-beta-D-glucopyranoside Indazole-4-boronic acid, hydrochloride
1H-Indazole-5-carbonitrile DL-Indole-3-lactic acid 1H-Indole-7-carboxylic acid Methyl 1H-indole-7-carboxylate Indole-7-carboxylic acid ethyl ester
Indole-4-carboxaldehyde Indole-3-carboxaldehyde Indole-5-carboxaldehyde

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1H-INDOLE-5-CARBALDEHYDE 7-Indolecarboxaldehyde 1H-Indole-7-carboxaldehyde (9CI) INDOLE-7-CARBOXALDEHYDE (7-FORMYLINDOLE) 1H-Indole-7-carboxaldehyde 7-Formyl-1H-indole Indole-7-carboxaldehyde,98% 1H-indol-7-carbaldehyde Indole-7-carboxaldehyde 97% RARECHEM AH BS 0111 INDOLE-7-CARBOXALDEHYDE INDOLE-7-CARBALDEHYDE INDOLE-7-ALDEHYDE 7-FORMYLINDOLE 7-Formylindole Indole-7-carboxaldehyde in stock Factory e-7-carboxaL Indole-7-carboxaldehyde ISO 9001：2015 REACH Indole-7-carboxaldehyde (7CI, 8CI) 7-Indolealdehyde 1H-INDOLE-7-CARBALDEHYDE 1074-88-0 Building Blocks Indoles Heterocyclic Building Blocks Heterocycle-Indole series ALDEHYDE Aldehydes blocks IndolesOxindoles Indoles and derivatives Indole Indoles Building Blocks Indole Derivatives