ChemicalBook >> CAS DataBase List >>Indole-7-carboxaldehyde

Indole-7-carboxaldehyde

CAS No.
1074-88-0
Chemical Name:
Indole-7-carboxaldehyde
Synonyms
1H-INDOLE-5-CARBALDEHYDE;1H-INDOLE-7-CARBALDEHYDE;e-7-carboxaL;7-FORMYLINDOLE;7-Indolealdehyde;INDOLE-7-ALDEHYDE;7-Formyl-1H-indole;RARECHEM AH BS 0111;INDOLE-7-CARBALDEHYDE;7-Indolecarboxaldehyde
CBNumber:
CB8731641
Molecular Formula:
C9H7NO
Molecular Weight:
145.16
MDL Number:
MFCD01318152
MOL File:
1074-88-0.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:28
Product description Number Pack Size Price
Indole-7-carboxaldehyde 97% 632414 1g $112
Indole-7-carboxaldehyde 97% 632414 5g $303
1H-Indole-7-carbaldehyde min. 98.0 % I0701 1G $57
1H-Indole-7-carbaldehyde min. 98.0 % I0701 5G $172
Indole-7-carboxaldehyde 280300 1g $396
More product size

Indole-7-carboxaldehyde Properties

Melting point 87-91 °C (lit.)
Boiling point 339.1±15.0 °C(Predicted)
Density 1.278±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane
pka 15.50±0.30(Predicted)
form Solid
color Yellow Crystalline
Water Solubility insoluble
Sensitive Air Sensitive
BRN 1524960
InChI InChI=1S/C9H7NO/c11-6-8-3-1-2-7-4-5-10-9(7)8/h1-6,10H
InChIKey XQVZDADGTFJAFM-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2C=O)C=C1
CAS DataBase Reference 1074-88-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330-P302+P352
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-43
Safety Statements  36/37
WGK Germany  3
10
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Skin Sens. 1
NFPA 704
1
2 0

Indole-7-carboxaldehyde price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 632414 Indole-7-carboxaldehyde 97% 1074-88-0 1g $112 2025-07-31 Buy
Sigma-Aldrich 632414 Indole-7-carboxaldehyde 97% 1074-88-0 5g $303 2023-06-20 Buy
TCI Chemical I0701 1H-Indole-7-carbaldehyde min. 98.0 % 1074-88-0 1G $57 2025-07-31 Buy
TCI Chemical I0701 1H-Indole-7-carbaldehyde min. 98.0 % 1074-88-0 5G $172 2025-07-31 Buy
Usbiological 280300 Indole-7-carboxaldehyde 1074-88-0 1g $396 2021-12-16 Buy
Product number Packaging Price Buy
632414 1g $112 Buy
632414 5g $303 Buy
I0701 1G $57 Buy
I0701 5G $172 Buy
280300 1g $396 Buy

Indole-7-carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Indole-7-carboxaldehyde is used in an efficient synthesis of fused pyrroloquinolinedicarboxylates from acetylenedicarboxylates and triphenylphosphine. 1.reactant for preparation of antiandrogens. 2.reactant for preparation of antiplatelet agent. 3.reactant for preparation of liver

Uses

Indole-7-carboxaldehyde (cas# 1074-88-0) is a compound useful in organic synthesis.

Definition

ChEBI: Indole-7-carboxaldehyde is a member of indoles.

Synthesis Reference(s)

Synthetic Communications, 36, p. 1051, 2006 DOI: 10.1080/00397910500503470

Synthesis

INDOLE-7-METHANOL

1074-87-9

Indole-7-carboxaldehyde

1074-88-0

General procedure for the synthesis of indole-7-carboxaldehyde from (1H-indol-7-yl)methanol: (1H-indol-7-yl)methanol (8.0 g, 54.3 mmol) was dissolved in 400 mL of dichloromethane, and activated manganese(IV) oxide (85%, 41.0 g, 0.40 mol) was added. The reaction mixture was stirred at room temperature for 72 hours. Upon completion of the reaction, 200 mL of dichloromethane and 400 mL of methanol were added to the mixture, followed by filtration through a silica gel pad to remove solid impurities. The filtrate was concentrated to give the crude product, which was further purified by silica gel column chromatography to afford the target product 1H-indole-7-carboxaldehyde (I-1) (6.55 g, 83% yield). The structure of the product was confirmed by 1H-NMR (CDCl3).

References

[1] Synthetic Communications, 2006, vol. 36, # 8, p. 1051 - 1056
[2] Patent: US2006/79520, 2006, A1. Location in patent: Page/Page column 43
[3] Patent: WO2006/44415, 2006, A2. Location in patent: Page/Page column 78; 106-107
[4] Journal of the American Chemical Society, 2006, vol. 128, # 12, p. 4023 - 4034
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 10, p. 4116 - 4125

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View Lastest Price from Indole-7-carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indole-7-carboxaldehyde pictures 2025-04-04 Indole-7-carboxaldehyde
1074-88-0
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
7-Formylindole  Indole-7-carboxaldehyde    in stock Factory pictures 2020-06-02 7-Formylindole Indole-7-carboxaldehyde in stock Factory
1074-88-0
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 largest production capacity Factory Chemwill Asia Co.,Ltd.
Indole-7-carboxaldehyde pictures 2019-12-26 Indole-7-carboxaldehyde
1074-88-0
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

Indole-7-carboxaldehyde Spectrum

1H-INDOLE-5-CARBALDEHYDE 1H-INDOLE-7-CARBALDEHYDE 7-Indolecarboxaldehyde 1H-Indole-7-carboxaldehyde (9CI) INDOLE-7-CARBOXALDEHYDE (7-FORMYLINDOLE) 1H-Indole-7-carboxaldehyde 7-Formyl-1H-indole Indole-7-carboxaldehyde,98% 1H-indol-7-carbaldehyde Indole-7-carboxaldehyde 97% RARECHEM AH BS 0111 INDOLE-7-CARBOXALDEHYDE INDOLE-7-CARBALDEHYDE INDOLE-7-ALDEHYDE 7-FORMYLINDOLE 7-Formylindole Indole-7-carboxaldehyde in stock Factory e-7-carboxaL Indole-7-carboxaldehyde ISO 9001:2015 REACH Indole-7-carboxaldehyde (7CI, 8CI) 7-Indolealdehyde 1074-88-0 Building Blocks Indoles Heterocyclic Building Blocks Heterocycle-Indole series ALDEHYDE Aldehydes blocks IndolesOxindoles Indoles and derivatives Indole Indoles Building Blocks Indole Derivatives