NEOMYCIN B
- CAS No.
- 119-04-0
- Chemical Name:
- NEOMYCIN B
- Synonyms
- framycetin;actilin;actiline;framygen;Framidal;Framycin;enterfram;Francetin;Fraquinol;soframycin
- CBNumber:
- CB8761428
- Molecular Formula:
- C23H46N6O13
- Molecular Weight:
- 614.64
- MDL Number:
- MFCD09788228
- MOL File:
- 119-04-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Neomycin solution with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture | N1142 | 20ml | $24.3 |
| Neomycin B | 460655 | 500ug | $545 |
| Neomycin B | 460655 | 1mg | $792 |
| Neomycin B | 460655 | 2.5mg | $1451 |
| Neomycin B Hexaacetate | TRC-N389990-5MG | 5mg | $313 |
| More product size | |||
| Melting point | >194°C (dec.) |
|---|---|
| Boiling point | 658.4°C (rough estimate) |
| Density | 1.3548 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | liquid |
| pka | 12.93±0.70(Predicted) |
| color | clear |
| biological source | Streptomyces fradiae |
| Merck | 13,6482 |
| Stability | Hygroscopic |
| InChIKey | PGBHMTALBVVCIT-VCIWKGPPSA-N |
| SMILES | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]4N)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O |
| EWG's Food Scores | 1 |
| FDA UNII | 4BOC774388 |
| ATC code | D09AA01,R01AX08,S01AA07 |
| UNSPSC Code | 12352207 |
| NACRES | NA.76 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H334 | |||||||||
| Precautionary statements | P261-P280-P284-P304+P340-P333+P313-P342+P311 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 42/43-63-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45-36/37-23 | |||||||||
| WGK Germany | 2 | |||||||||
| F | 8 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Resp. Sens. 1 Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
NEOMYCIN B price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1142 | Neomycin solution with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture | 119-04-0 | 20ml | $24.3 | 2026-04-30 | Buy |
| Usbiological | 460655 | Neomycin B | 119-04-0 | 500ug | $545 | 2026-06-03 | Buy |
| Usbiological | 460655 | Neomycin B | 119-04-0 | 1mg | $792 | 2026-06-03 | Buy |
| Usbiological | 460655 | Neomycin B | 119-04-0 | 2.5mg | $1451 | 2026-06-03 | Buy |
| TRC | TRC-N389990-5MG | Neomycin B Hexaacetate | 119-04-0 | 5mg | $313 | 2026-06-03 | Buy |
NEOMYCIN B Chemical Properties,Uses,Production
Uses
Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
Definition
ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.
General Description
Chemical structure: aminoglycoside
Biochem/physiol Actions
Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria
IC 50
Aminoglycoside
NEOMYCIN B Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
119-04-0(NEOMYCIN B)Related Search:
1of4
