3-Bromo-2-(bromomethyl)propionic acid
- CAS No.
- 41459-42-1
- Chemical Name:
- 3-Bromo-2-(bromomethyl)propionic acid
- Synonyms
- 3-BROMO-2-(BROMOMETHYL)PROPANOIC ACID;3-Bromo-2-(bromomethyl);3-Bromo-2-(bromomethyl)pr;β,β'-dibromoisobutyric acid;bis(bromomethyl)acetic acid;3-Bromo-2-Bromomethyl Propionate;BETA,BETA'-DIBROMOISOBUTYRIC ACID;3-BROMO-2-(BROMOMETHYL)PROPIONIC ACID;Propanoic acid, 3-bromo-2-(bromomethyl)-;3-Bromo-2-(bromomethyl)propionic acid 97%
- CBNumber:
- CB8780427
- Molecular Formula:
- C4H6Br2O2
- Molecular Weight:
- 245.9
- MDL Number:
- MFCD00010643
- MOL File:
- 41459-42-1.mol
- MSDS File:
- SDS
| Melting point | 98-101 °C(lit.) |
|---|---|
| Boiling point | 286.7±30.0 °C(Predicted) |
| Density | 2.121±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in acetic acid. |
| form | Crystalline Powder |
| pka | 3.33±0.11(Predicted) |
| color | Off-white to brown |
| BRN | 1752505 |
| InChI | InChI=1S/C4H6Br2O2/c5-1-3(2-6)4(7)8/h3H,1-2H2,(H,7,8) |
| InChIKey | QQZJWQCLWOQDQV-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(CBr)CBr |
| CAS DataBase Reference | 41459-42-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Propionic acid, 3-bromo-2-(bromomethyl)-(41459-42-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
3-Bromo-2-(bromomethyl)propionic acid price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 301620 | 3-Bromo-2-(bromomethyl)propionic acid 97% | 41459-42-1 | 5g | $78.3 | 2023-06-20 | Buy |
| TCI Chemical | B3081 | 3-Bromo-2-(bromomethyl)propionic Acid >98.0%(T) | 41459-42-1 | 5g | $56 | 2026-04-30 | Buy |
| TCI Chemical | B3081 | 3-Bromo-2-(bromomethyl)propionic Acid >98.0%(T) | 41459-42-1 | 25g | $216 | 2026-04-30 | Buy |
| Usbiological | 264166 | 3-Bromo-2-bromomethyl-propionic acid Asreported | 41459-42-1 | 10g | $223 | 2026-06-03 | Buy |
| Usbiological | 264166 | 3-Bromo-2-bromomethyl-propionic acid Asreported | 41459-42-1 | 25g | $329 | 2026-06-03 | Buy |
3-Bromo-2-(bromomethyl)propionic acid Chemical Properties, Uses, Production
Chemical Properties
off-white to brown crystalline powder
Uses
3-Bromo-2-(bromomethyl)propionic acid acts as an organic building block for the preparation of beta-substituted acrylates. It is used in the preparation of t-butyl 2-(phenylthiomethyl) propenoate, t-butyl 3-(phenylthio)-2-(phenylthiomethyl)propenoate and 3-(phenylthio)-2-(phenyl-sulfinylmethyl)propenoate. Further, it plays an important role in the synthesis of beta-lactams by cyclization of the corresponding amide.
General Description
3-Bromo-2-(bromomethyl)propionic acid reacts with alkaline arsenite to yield (RS)-3-arsono-2-(hydroxymethyl)propionic acid.
Synthesis
A mixture of commercially available diethyl bis(hydroxymethyl)malonate (25 g., 0.11 mol.) and a 48% aqueous hydrogen bromide solution (192 cm3, 1.70 mol) was heated until the ethyl bromide liquid began to evaporate from the mixture and then vigorously distilled for about 1 h. The reaction mixture was refluxed at 140C for 5 hours. The solution is cooled in an ice bath for 1. 5 hours. The crystals formed were filtered, washed with a small amount of ice-cold water and dried under vacuum. About 80 cm3 was distilled out of the of the filtrate, the solution was cooled in ice to produce another batch of crystals, washed and dried as before to give 3-bromo-2-bromomethylpropionic acid.
3-Bromo-2-(bromomethyl)propionic acid Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
3-Bromo-2-(bromomethyl)propionic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Baiyin Chengze Chemical Technology Co., Ltd. | +86 943-8535351 13389336721 | sales@chengzechem.com | China | 300 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
View Latest Price from 3-Bromo-2-(bromomethyl)propionic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-01-09 | 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Bromo-2-(bromomethyl)propionic acid
41459-42-1
- $9.80
- ≥99%
- Career Henan Chemical Co
