4-(2,2,2-Trifluoroethoxy)phenylboronic acid
- CAS No.
- 886536-37-4
- Chemical Name:
- 4-(2,2,2-Trifluoroethoxy)phenylboronic acid
- Synonyms
- (4-(2,2,2-Trifluoroethoxy);4-(2,2,2-trifluoroethoxy)phenyboronic acid;4-(2,2,2-Trifluoroethoxy)phenylboronic acid;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid;4-(2,2,2-Trifluoroethoxy)benzeneboronicacid98%;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98%;Boronic acid, B-[4-(2,2,2-trifluoroethoxy)phenyl]-;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid, [4-(2,2,2-Trifluoroethoxy)phenyl]boronic acid
- CBNumber:
- CB8837293
- Molecular Formula:
- C8H8BF3O3
- Molecular Weight:
- 219.95
- MDL Number:
- MFCD09027239
- MOL File:
- 886536-37-4.mol
- MSDS File:
- SDS
| Melting point | 191-194℃ |
|---|---|
| Boiling point | 297.1±50.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 8.58±0.16(Predicted) |
| color | White |
| InChI | InChI=1S/C8H8BF3O3/c10-8(11,12)5-15-7-3-1-6(2-4-7)9(13)14/h1-4,13-14H,5H2 |
| InChIKey | DWRAMTYYMNLVBD-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(OCC(F)(F)F)C=C1)(O)O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
4-(2,2,2-Trifluoroethoxy)phenylboronic acid price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC7094 | 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98% | 886536-37-4 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC7094 | 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98% | 886536-37-4 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC7094 | 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98% | 886536-37-4 | 5g | $58 | 2026-06-04 | Buy |
| Apolloscientific | PC7094 | 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98% | 886536-37-4 | 25g | $196 | 2026-06-04 | Buy |
| Activate Scientific | AS27411 | 4-(2,2,2-Trifluoroethoxy)phenylboronic Acid 95% | 886536-37-4 | 1g | $32 | 2026-06-04 | Buy |
4-(2,2,2-Trifluoroethoxy)phenylboronic acid Chemical Properties, Uses, Production
Uses
4-(2,2,2-Trifluoroethoxy)phenylboronic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
2- (2,2,2-trifluoroethoxy) bromobenzene 2558, isopropyl borate 2448 and methylTetrahydrofuran 1.5L was added to the reaction flask, and the reaction system was cooled to -15 ° C. 500 mL of isopropylmagnesium chloride in tetrahydrofuran (2.0 M) was added dropwise to the above reaction system and the internal temperature was controlled to not more than -10 ° C, and the reaction was kept at a low temperature for 1 hour. After completion of the reaction, 500 mL of 6M aqueous hydrochloric acid solution was added to terminate the reaction and the ρH- = 2 ~ 3 was added, and the mixture was thoroughly stirred and the aqueous phase was extracted with methyltetrahydrofuran (1.5 LX 1). The combined organic layers were washed with saturated brine (1.5 LX 2), and the combined organic layers were dried over anhydrous sodium sulfate and concentrated to give the crude product of 2- (2,2,2-trifluoroethoxy) phenylboronic acid. The crude product was recrystallized from 770 mL of isopropanol and water (10: 1 by volume) to give 187 g of 2- (2,2,2-trifluoroethoxy) phenylboronic acid in a molar yield of 85%.
4-(2,2,2-Trifluoroethoxy)phenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Sun-shine Bio-technology Corporation Limited | +86-027-6552-2453 | sales@sun-shinechem.com | China | 725 | 58 |
| Suzhou Jinglige Technology Co., Ltd | 18551175068 | jinglige888@163.com | China | 248 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| DKD Shijiazhuang Chemical Co., Ltd. | 0311-67790228 15531158659 | 2361184479@qq.com | China | 300 | 62 |
| Changzhou Chemscaler Pharmtech Co., Ltd. | 0519-81096292 15312577869 | chemscaler@yahoo.com.cn | China | 300 | 60 |
View Latest Price from 4-(2,2,2-Trifluoroethoxy)phenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-06-20 | 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
|
1kg | 99.50% | 20tons | Hebei Yanxi Chemical Co., Ltd. | ||
 |
2023-11-27 | 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
|
1Kg | 98% | 2000 Kg | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD |
-
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
- $0.00
- 99.50%
- Hebei Yanxi Chemical Co., Ltd.
-
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
886536-37-4
- 98%
- SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD
