TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
- CAS No.
- 207799-10-8
- Chemical Name:
- TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
- Synonyms
- tert-Butyl N-(4-bromo-2-pyridyl)carbamate;2-(Boc-amino)-4-bromopyridine;RESTORE?, each (250 mL/bottle);t-Butyl 4-bromopyridin-2-ylcarbamate;TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE;Tert-butyl-4-Bromo Pyrion-2-yl-Carbamate;ert-butylN-(4-bromopyridin-2-yl)carbamate;tert-butyl N-(4-broMopyridin-2-yl)carbaMate;(4-Bromo-pyridin-2-yl)-carbamic acid tert-butyl ester;TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE ISO 9001:2015 REACH
- CBNumber:
- CB8847771
- Molecular Formula:
- C10H13BrN2O2
- Molecular Weight:
- 273.13
- MDL Number:
- MFCD09037866
- MOL File:
- 207799-10-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl-4-bromo(pyridin-2-yl)carbamate ≥95% | OR302007 | 1g | $78 |
| tert-Butyl-4-bromo(pyridin-2-yl)carbamate ≥95% | OR302007 | 5g | $168 |
| tert-Butyl (4-bromopyridin-2-yl)carbamate | 072443 | 1.00g | $310 |
| tert-Butyl (4-bromopyridin-2-yl)carbamate | 072443 | 5.00g | $993 |
| Tert-butyl (4-bromopyridin-2-yl)carbamate 87% | B8883 | 250mg | $14 |
| More product size | |||
| Boiling point | 296.7±25.0 °C(Predicted) |
|---|---|
| Density | 1.453±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| pka | 11.89±0.70(Predicted) |
| Appearance | White to light brown Solid |
| InChI | InChI=1S/C10H13BrN2O2/c1-10(2,3)15-9(14)13-8-6-7(11)4-5-12-8/h4-6H,1-3H3,(H,12,13,14) |
| InChIKey | IRRRVCLDPODLJG-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NC1=NC=CC(Br)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR302007 | tert-Butyl-4-bromo(pyridin-2-yl)carbamate ≥95% | 207799-10-8 | 1g | $78 | 2026-06-04 | Buy |
| Apolloscientific | OR302007 | tert-Butyl-4-bromo(pyridin-2-yl)carbamate ≥95% | 207799-10-8 | 5g | $168 | 2026-06-04 | Buy |
| Matrix Scientific | 072443 | tert-Butyl (4-bromopyridin-2-yl)carbamate | 207799-10-8 | 1.00g | $310 | 2026-05-18 | Buy |
| Matrix Scientific | 072443 | tert-Butyl (4-bromopyridin-2-yl)carbamate | 207799-10-8 | 5.00g | $993 | 2026-05-18 | Buy |
| Synthonix | B8883 | Tert-butyl (4-bromopyridin-2-yl)carbamate 87% | 207799-10-8 | 250mg | $14 | 2026-05-06 | Buy |
TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE Chemical Properties,Uses,Production
Uses
tert-butyl (4-bromopyrimidin-2-yl)carbamate can be used as a pharmaceutical synthesis intermediate.
Synthesis
84249-14-9
24424-99-5
207799-10-8
General procedure for the synthesis of 2-Boc amine-4-bromopyridine from 2-amino-4-bromopyridine and di-tert-butyl dicarbonate: To a solution of 4-bromopyridin-2-amine (519 mg) in anhydrous THF (15 mL) was slowly added bis(trimethylmethylsilyl)amide (1 M solution in hexane, 6 mL) at -5 °C and the reaction mixture was stirred. After maintaining this temperature for 10 minutes, di-tert-butyl dicarbonate (654 mg) was added and the reaction mixture was transferred to room temperature to continue stirring for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of saturated ammonium chloride solution (20 mL) and the mixture was extracted with EtOAc. The organic layers were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target product 2-Boc amine-4-bromopyridine in 96% yield.
References
[1] Patent: US2014/194443, 2014, A1. Location in patent: Paragraph 0541-0542
[2] Patent: WO2014/108337, 2014, A1. Location in patent: Page/Page column 69
[3] Patent: WO2016/124508, 2016, A1. Location in patent: Page/Page column 39
[4] Journal of Medicinal Chemistry, 2017, vol. 60, # 13, p. 5613 - 5637
[5] Patent: CN104744433, 2016, B. Location in patent: Paragraph 0027; 0028
TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29094 | 58 |
View Lastest Price from TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
207799-10-8
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2019-07-06 | TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
207799-10-8
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-

- TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
207799-10-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE
207799-10-8
- $8.80
- 97%-99%
- Career Henan Chemical Co






