ChemicalBook >> CAS DataBase List >>2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE

CAS No.
237435-16-4
Chemical Name:
2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE
Synonyms
6-bromo-2,4-dichloro-3-Pyridinamine;6-bromo-2,4-dichloropyridin-3-amine;3-Pyridinamine,6-bromo-2,4-dichloro-;2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE;6-Bromo-2,4-dichloro-pyridin-3-ylamine;3-Amino-6-bromo-2,4-dichloropyridine 98%
CBNumber:
CB91075998
Molecular Formula:
C5H3BrCl2N2
Molecular Weight:
241.9
MDL Number:
MFCD09750300
MOL File:
237435-16-4.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Properties

Boiling point 301.2±37.0 °C(Predicted)
Density 1.934±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -2.02±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933399990

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR345304 3-Amino-6-bromo-2,4-dichloropyridine 98% 237435-16-4 100mg $89 2021-12-16 Buy
SynQuest Laboratories 3H30-D-26 3-Amino-6-bromo-2,4-dichloropyridine 237435-16-4 100mg $98 2021-12-16 Buy
Apolloscientific OR345304 3-Amino-6-bromo-2,4-dichloropyridine 98% 237435-16-4 250mg $141 2021-12-16 Buy
SynQuest Laboratories 3H30-D-26 3-Amino-6-bromo-2,4-dichloropyridine 237435-16-4 250mg $156 2021-12-16 Buy
AK Scientific 1639AB 3-Amino-6-bromo-2,4-dichloropyridine 237435-16-4 250mg $188 2021-12-16 Buy
Product number Packaging Price Buy
OR345304 100mg $89 Buy
3H30-D-26 100mg $98 Buy
OR345304 250mg $141 Buy
3H30-D-26 250mg $156 Buy
1639AB 250mg $188 Buy

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Chemical Properties,Uses,Production

Synthesis

2,4-DICHLORO-3-AMINOPYRIDINE

173772-63-9

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE

237435-16-4

(d) Synthesis of 3-amino-6-bromo-2,4-dichloropyridine. 3-Amino-2,4-dichloropyridine (500 mg, 3.1 mmol) was dissolved in N,N-dimethylformamide (DMF, 16 mL) and cooled to 0 °C in an ice-water bath. Subsequently, a solution of N-bromosuccinimide (660 mg, 3.7 mmol) in DMF (7 mL) was slowly added dropwise. After 15 min of reaction, the reaction mixture was poured into water and extracted with ethyl acetate (EtOAc, 2×). The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give a red residue. The residue was dissolved in a mixed solvent of ethyl acetate/hexane with a volume ratio of 1:1, filtered through a silica gel short column, and concentrated again under reduced pressure to give 0.68 g of the title compound in colorless crystalline form (90% yield). 1H NMR (DMSO-d6, 500 MHz): δ 6.10 (s, 2H), 7.69 (s, 1H). Mass spectrum (MS) m/z: 243 ([M+H]+, 81Br), 241 ([M+H]+, 79Br).

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4288 - 4312
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1511 - 1530
[3] MedChemComm, 2016, vol. 7, # 5, p. 1022 - 1032
[4] Patent: US6187777, 2001, B1

5975-12-2
237435-16-4
Synthesis of 2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE from 2,4-Dichloro-3-nitropyridine

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Preparation Products And Raw materials

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED
+8618795957998 karmelhk@126.com CHINA 2886 58
Hunan Jibang Biological Technology Co., LTD
+8613776644403 sales02@kingboomtech.com China 1804 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Suzhou ARTK Medchem Co., Ltd.
+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39003 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 sales@capotchem.com China 18207 66
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3987 55
SynAsst Chemical. 021-60343070 China 12740 55

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Spectrum

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE 3-Pyridinamine,6-bromo-2,4-dichloro- 6-bromo-2,4-dichloropyridin-3-amine 6-bromo-2,4-dichloro-3-Pyridinamine 6-Bromo-2,4-dichloro-pyridin-3-ylamine 3-Amino-6-bromo-2,4-dichloropyridine 98% 237435-16-4 Pyridine