2-Aminothiazole-5-carboxylic acid
- CAS No.
- 40283-46-3
- Chemical Name:
- 2-Aminothiazole-5-carboxylic acid
- Synonyms
- 2-AMINO-5-THIAZOLECARBOXYLIC ACID;RARECHEM AL BE 1263;2-Amino-5-carboxy-1,3-thiazole;2-Aminothizole-5-carboxylic acid;2-Aminothiazole-5-carboxylic acid;Heterocyclic coMpounds / Pyrazole;2-AMINOTHIAZOL-5-YLCARBOXYLIC ACID;5-Thiazolecarboxylic acid, 2-aMino-;2-Amino-1,3-thiazole-5-carboxylic acid;2-Aminothiazole-5-carboxylic acid, >=98%
- CBNumber:
- CB9116986
- Molecular Formula:
- C4H4N2O2S
- Molecular Weight:
- 144.15
- MDL Number:
- MFCD06203554
- MOL File:
- 40283-46-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| Hazard Note | Irritant/Keep Cold |
| HS Code | 29341000 |
2-Aminothiazole-5-carboxylic acid price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 260190 | 2-Aminothiazole-5-carboxylic acid Asreported | 40283-46-3 | 5g | $389 | 2026-06-03 | Buy |
| Usbiological | 260190 | 2-Aminothiazole-5-carboxylic acid Asreported | 40283-46-3 | 10g | $581 | 2026-06-03 | Buy |
| Usbiological | 260190 | 2-Aminothiazole-5-carboxylic acid Asreported | 40283-46-3 | 25g | $832 | 2026-06-03 | Buy |
| Biosynth | FA36283 | 2-Aminothiazole-5-carboxylic acid | 40283-46-3 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FA36283 | 2-Aminothiazole-5-carboxylic acid | 40283-46-3 | 10g | $210.4 | 2026-06-04 | Buy |
2-Aminothiazole-5-carboxylic acid Chemical Properties, Uses, Production
Synthesis
32955-21-8
40283-46-3
General procedure for the synthesis of 2-aminothiazole-5-carboxylic acid from ethyl 2-aminothiazole-5-carboxylate: sodium hydroxide (0.65 g, 16.3 mmol) was added to a mixed THF/water (2:1, v/v) solution containing ethyl 2-aminothiazole-5-carboxylate (0.80 g, 4.32 mmol) and the reaction mixture was heated to reflux overnight. Upon completion of the reaction, THF was removed by distillation under reduced pressure.Subsequently, the reaction mixture was neutralized with 1 M hydrochloric acid solution. The resulting precipitate was collected by filtration, washed with ether and dried at 60 °C overnight. An off-white crystalline product was obtained in 86% yield with a melting point of 168-171 °C (literature value: 172-173 °C). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.81 (s, 1H, thiazole-H), 8.99 (br s, 2H, NH2) ppm. high-resolution mass spectrometry (HRMS-ESI) analysis: m/z [M+H]+ calculated value of 145.1475 (C4H5N2O2S), measured value 145.1502.
References
[1] European Journal of Medicinal Chemistry, 2013, vol. 67, p. 208 - 220
[2] Recueil des Travaux Chimiques des Pays-Bas, 1944, vol. 63, p. 226
[3] Yakugaku Zasshi, 1948, vol. 68, p. 101
[4] Chem.Abstr., 1953, p. 7452
[5] Chemische Berichte, 1943, vol. 76, p. 419,428
2-Aminothiazole-5-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Pope Bio-tech R&D Co., Ltd | 025-87138562 18951783565 | sales@popebiotech.com | China | 1180 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from 2-Aminothiazole-5-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID
40283-46-3
|
$150.00 | 1KG | 98% | 20KG | Career Henan Chemical Co |
-
- 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID
40283-46-3
- $150.00
- 98%
- Career Henan Chemical Co
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