Ethyl 2-aminothiazole-5-carboxylate
- CAS No.
- 32955-21-8
- Chemical Name:
- Ethyl 2-aminothiazole-5-carboxylate
- Synonyms
- BUTTPARK 77\50-04;RARECHEM AL BI 1263;2-aMinothiazole-5-Ethyl;ETHYL 2-AMINO-5-CARBOXLATE;2-aMino-5-thiazolecarboxylate;Ethyl-2-aminothiazole-5-carbonylate;ETHYL 2-AMINOTHIAZOLE-5-CARBOXYLATE;Ethyl 2-amino-5-thiazolecarboxylate;ethyl 2-Aminothiozole-5-carboxylate;2-AMINOTHIAZOLE-5-ETHYL CARBOXYLATE
- CBNumber:
- CB8303716
- Molecular Formula:
- C6H8N2O2S
- Molecular Weight:
- 172.2
- MDL Number:
- MFCD00602139
- MOL File:
- 32955-21-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 144-148 |
|---|---|
| Boiling point | 308.0±15.0 °C(Predicted) |
| Density | 1.336±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| Water Solubility | Insoluble in water |
| pka | 3.12±0.10(Predicted) |
| form | powder to crystal |
| color | White to Yellow to Orange |
| Sensitive | Moisture & Light Sensitive |
| λmax | 299nm(EtOH)(lit.) |
| InChI | InChI=1S/C6H8N2O2S/c1-2-10-5(9)4-3-8-6(7)11-4/h3H,2H2,1H3,(H2,7,8) |
| InChIKey | VNZXERIGKZNEKB-UHFFFAOYSA-N |
| SMILES | S1C(C(OCC)=O)=CN=C1N |
| CAS DataBase Reference | 32955-21-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Ethyl 2-aminothiazole-5-carboxylate price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 708437 | Ethyl 2-aminothiazole-5-carboxylate 97% | 32955-21-8 | 5g | $281 | 2026-04-30 | Buy |
| Sigma-Aldrich | 708437 | Ethyl 2-aminothiazole-5-carboxylate 97% | 32955-21-8 | 1g | $54 | 2023-06-20 | Buy |
| TCI Chemical | E0907 | Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) | 32955-21-8 | 1g | $22 | 2026-04-30 | Buy |
| TCI Chemical | E0907 | Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) | 32955-21-8 | 5g | $31 | 2026-04-30 | Buy |
| AstaTech | 65024 | ETHYL 2-AMINO-THIAZOLE-5-CARBOXYLATE 95% | 32955-21-8 | 250G | $67 | 2026-04-30 | Buy |
Ethyl 2-aminothiazole-5-carboxylate Chemical Properties, Uses, Production
Chemical Properties
White to yellow or light brown crystal or powder
Uses
2-Amino-5-thiazolecarboxylic Acid Ethyl Ester is used in the synthesis of dual-action antidiabetic agents that inhibit glycogen phosphorylase.
Synthesis Reference(s)
Tetrahedron Letters, 42, p. 2101, 2001 DOI: 10.1016/S0040-4039(01)00161-7
Synthesis
1001-26-9
17356-08-0
32955-21-8
1. N-bromosuccinimide (19.6 g, 0.11 mol) was slowly added to a water/dioxane (1:1, 100 mL) solution of ethyl 3-ethoxyacrylate (14.4 g, 0.1 mol) at -10 °C. 2. The reaction mixture was stirred at room temperature for 1 h. 3. After the addition of thiourea (7.6 g, 0.1 mol), the reaction mixture was was heated to 80 °C and maintained for 1 h. 4. Upon completion of the reaction, the solution was cooled to room temperature followed by the addition of ammonia (20 mL). 5. The resulting paste was stirred at room temperature for 10 min and then filtered. 6. The filter cake was washed with water and dried under vacuum to give the final product, ethyl 2-aminothiazole-5-carboxylate (12.1 g, 70% yield).
References
[1] Patent: EP2615092, 2013, A1. Location in patent: Paragraph 0095; 0096
[2] Patent: WO2006/8556, 2006, A1. Location in patent: Page/Page column 20-21
Ethyl 2-aminothiazole-5-carboxylate Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai ChemIDo Co., Ltd. | 19301251526 | sales@chemido.com | China | 69 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ChangShu Haitian Fine Chemicals Co.,Ltd | 13913622609 | 974295387@qq.com | China | 192 | 61 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from Ethyl 2-aminothiazole-5-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-15 | Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
|
100g | 98%min | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-28 | Ethyl 2-Aminothiazole-5-Carboxylate
32955-21-8
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-05-07 | Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
|
99% | 5 tons | Suzhou Nordica Biopharma CO.,LTD |
-
- Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Ethyl 2-Aminothiazole-5-Carboxylate
32955-21-8
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
- 99%
- Suzhou Nordica Biopharma CO.,LTD
