ChemicalBook >> CAS DataBase List >>Ethyl 2-aminothiazole-5-carboxylate

Ethyl 2-aminothiazole-5-carboxylate

CAS No.
32955-21-8
Chemical Name:
Ethyl 2-aminothiazole-5-carboxylate
Synonyms
BUTTPARK 77\50-04;RARECHEM AL BI 1263;2-aMinothiazole-5-Ethyl;ETHYL 2-AMINO-5-CARBOXLATE;2-aMino-5-thiazolecarboxylate;Ethyl-2-aminothiazole-5-carbonylate;ETHYL 2-AMINOTHIAZOLE-5-CARBOXYLATE;Ethyl 2-amino-5-thiazolecarboxylate;ethyl 2-Aminothiozole-5-carboxylate;2-AMINOTHIAZOLE-5-ETHYL CARBOXYLATE
CBNumber:
CB8303716
Molecular Formula:
C6H8N2O2S
Molecular Weight:
172.2
MDL Number:
MFCD00602139
MOL File:
32955-21-8.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:13
Product description Number Pack Size Price
Ethyl 2-aminothiazole-5-carboxylate 97% 708437 5g $132
Ethyl 2-aminothiazole-5-carboxylate 97% 708437 1g $54
Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) E0907 1g $33
Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) E0907 5g $38
2-Amino-5-thiazolecarboxylicAcidEthylEster A630420 2.5g $120
More product size

Ethyl 2-aminothiazole-5-carboxylate Properties

Melting point 144-148
Boiling point 308.0±15.0 °C(Predicted)
Density 1.336±0.06 g/cm3(Predicted)
storage temp. 2-8°C
Water Solubility Insoluble in water
pka 3.12±0.10(Predicted)
form powder to crystal
color White to Yellow to Orange
λmax 299nm(EtOH)(lit.)
Sensitive Moisture & Light Sensitive
InChI InChI=1S/C6H8N2O2S/c1-2-10-5(9)4-3-8-6(7)11-4/h3H,2H2,1H3,(H2,7,8)
InChIKey VNZXERIGKZNEKB-UHFFFAOYSA-N
SMILES S1C(C(OCC)=O)=CN=C1N
CAS DataBase Reference 32955-21-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  2
HazardClass  IRRITANT
HS Code  29339900
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

Ethyl 2-aminothiazole-5-carboxylate price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 708437 Ethyl 2-aminothiazole-5-carboxylate 97% 32955-21-8 5g $132 2025-07-31 Buy
Sigma-Aldrich 708437 Ethyl 2-aminothiazole-5-carboxylate 97% 32955-21-8 1g $54 2023-06-20 Buy
TCI Chemical E0907 Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) 32955-21-8 1g $33 2025-07-31 Buy
TCI Chemical E0907 Ethyl 2-Aminothiazole-5-carboxylate >97.0%(HPLC)(T) 32955-21-8 5g $38 2025-07-31 Buy
TRC A630420 2-Amino-5-thiazolecarboxylicAcidEthylEster 32955-21-8 2.5g $120 2021-12-16 Buy
Product number Packaging Price Buy
708437 5g $132 Buy
708437 1g $54 Buy
E0907 1g $33 Buy
E0907 5g $38 Buy
A630420 2.5g $120 Buy

Ethyl 2-aminothiazole-5-carboxylate Chemical Properties,Uses,Production

Chemical Properties

White to yellow or light brown crystal or powder

Uses

2-Amino-5-thiazolecarboxylic Acid Ethyl Ester is used in the synthesis of dual-action antidiabetic agents that inhibit glycogen phosphorylase.

Synthesis Reference(s)

Tetrahedron Letters, 42, p. 2101, 2001 DOI: 10.1016/S0040-4039(01)00161-7

Synthesis

Ethyl 3-ethoxyacrylate

1001-26-9

Carbamimidothioic acid

17356-08-0

Ethyl 2-aminothiazole-5-carboxylate

32955-21-8

1. N-bromosuccinimide (19.6 g, 0.11 mol) was slowly added to a water/dioxane (1:1, 100 mL) solution of ethyl 3-ethoxyacrylate (14.4 g, 0.1 mol) at -10 °C. 2. The reaction mixture was stirred at room temperature for 1 h. 3. After the addition of thiourea (7.6 g, 0.1 mol), the reaction mixture was was heated to 80 °C and maintained for 1 h. 4. Upon completion of the reaction, the solution was cooled to room temperature followed by the addition of ammonia (20 mL). 5. The resulting paste was stirred at room temperature for 10 min and then filtered. 6. The filter cake was washed with water and dried under vacuum to give the final product, ethyl 2-aminothiazole-5-carboxylate (12.1 g, 70% yield).

References

[1] Patent: EP2615092, 2013, A1. Location in patent: Paragraph 0095; 0096
[2] Patent: WO2006/8556, 2006, A1. Location in patent: Page/Page column 20-21

1001-26-9
57-13-6
32955-21-8
Synthesis of Ethyl 2-aminothiazole-5-carboxylate from Ethyl 3-ethoxyacrylate and Urea
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View Lastest Price from Ethyl 2-aminothiazole-5-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 2-aminothiazole-5-carboxylate pictures 2026-01-22 Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
US $0.00-0.00 / Kg/Bag 100g 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Ethyl 2-Aminothiazole-5-Carboxylate pictures 2025-05-26 Ethyl 2-Aminothiazole-5-Carboxylate
32955-21-8
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Ethyl 2-aminothiazole-5-carboxylate pictures 2025-05-07 Ethyl 2-aminothiazole-5-carboxylate
32955-21-8
US $0.00-0.00 / kg 0.1kg 99% 5 tons Suzhou Nordica Biopharma CO.,LTD

Ethyl 2-aminothiazole-5-carboxylate Spectrum

2-AMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 2-AMINO-THIAZOLE-5-CARBOXYLATE ETHYL ESTER ETHYL 2-AMINOTHIAZOLE-5-CARBOXYLATE ETHYL 2-AMINO-1,3-THIAZOLE-5-CARBOXYLATE BUTTPARK 77\50-04 RARECHEM AL BI 1263 Thiazole,2-amino-5-carboxylic acid ethyl ester Ethyl-2-aminothiazole-5-carbonylate Ethyl 2-amino-1,3-thiazole-5-carboxylate 98% 2-aminothiazole-5-carboxylate 2-amino-1,3-thia ETHYL 2-AMINO-5-CARBOXLATE 5-Thiazolecarboxylic acid, 2-amino-, ethyl ester ETHYL 2-AMINO-1,3-THIAZOLE-5-CARBOXYLATE HYDROBROMIDE Ethyl 2-aminothiazole-5-carboxylate ,97% 2-aMino-5-thiazolecarboxylic acid, ethyl ester Ethyl 2-amino-5-thiazolecarboxylate 2-aMino-5-thiazolecarboxylate 2-aMinothiazole-5-Ethyl ethyl 2-Aminothiozole-5-carboxylate Ethyl2-Aminothiazole-5-carboxylate> TIANFUCHEM-- 32955-21-8 -- Ethyl 2-aminothiazole-5-carboxylate in stock 5-Thiazolecarboxylic acid, 2-amino-, ethyl ester (6CI, 9CI, ACI) 2-amino-5-Thiazolecarboxylic acid ethyl ester (6CI 9CI ACI) 2-AMINOTHIAZOLE-5-ETHYL CARBOXYLATE Ethyl 2-amino-thiazol-5-carboxylate 32955-21-8 2955-21-8 32995-21-8 32599-21-8 Amines and Anilines Heterocycles Carboxes Thiazoles Thiazole series Thiazole Heterocycle intermediates Amines blocks